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The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology.

Autor: Risbridger GP; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia. gail.risbridger@monash.edu.; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. gail.risbridger@monash.edu., Clark AK; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Porter LH; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Toivanen R; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Bakshi A; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Lister NL; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Pook D; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Department of Medicine, School of Clinical Sciences, Monash University, Clayton, VIC, Australia.; Department of Medical Oncology, Monash Health, Clayton, VIC, Australia., Pezaro CJ; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Eastern Health and Monash University Eastern Health Clinical School, Box Hill, VIC, Australia.; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, England., Sandhu S; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Cancer Tissue Collection After Death (CASCADE) Program, Melbourne, VIC, Australia., Keerthikumar S; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Quezada Urban R; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Papargiris M; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Australian Prostate Cancer Bioresource, VIC Node, Monash University, Clayton, VIC, Australia., Kraska J; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Australian Prostate Cancer Bioresource, VIC Node, Monash University, Clayton, VIC, Australia., Madsen HB; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Australian Prostate Cancer Bioresource, VIC Node, Monash University, Clayton, VIC, Australia., Wang H; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Richards MG; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Niranjan B; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., O'Dea S; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Teng L; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Wheelahan W; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Li Z; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Physiology, Monash University, Clayton, VIC, Australia., Choo N; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia., Ouyang JF; Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore, Singapore., Thorne H; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Devereux L; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Hicks RJ; Center for Molecular Imaging, Peter MacCallum Cancer Center, Melbourne, VIC, Australia., Sengupta S; Eastern Health and Monash University Eastern Health Clinical School, Box Hill, VIC, Australia.; Department of Urology, Austin Hospital, The University of Melbourne, Heidelberg, VIC, Australia.; Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, VIC, Australia.; Epworth Healthcare, Melbourne, VIC, Australia.; Epworth Freemasons, Epworth Health, East Melbourne, VIC, Australia., Harewood L; Epworth Healthcare, Melbourne, VIC, Australia.; Department of Surgery, The University of Melbourne, Parkville, VIC, Australia., Iddawala M; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Department of Medicine, School of Clinical Sciences, Monash University, Clayton, VIC, Australia., Azad AA; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Goad J; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Epworth Healthcare, Melbourne, VIC, Australia.; Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC, Australia., Grummet J; Epworth Healthcare, Melbourne, VIC, Australia.; Department of Surgery, Central Clinical School, Monash University, Clayton, VIC, Australia.; Australian Urology Associates, Melbourne, VIC, Australia., Kourambas J; Department of Medicine, Monash Health, Casey Hospital, Berwick, VIC, Australia., Kwan EM; Department of Medicine, School of Clinical Sciences, Monash University, Clayton, VIC, Australia.; Department of Medical Oncology, Monash Health, Clayton, VIC, Australia., Moon D; Epworth Healthcare, Melbourne, VIC, Australia.; Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC, Australia.; Australian Urology Associates, Melbourne, VIC, Australia.; Central Clinical School, Monash University, Clayton, VIC, Australia.; The Epworth Prostate Centre, Epworth Hospital, Richmond, VIC, Australia., Murphy DG; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Epworth Healthcare, Melbourne, VIC, Australia.; Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Melbourne, VIC, Australia., Pedersen J; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; TissuPath, Mount Waverley, VIC, Australia., Clouston D; TissuPath, Mount Waverley, VIC, Australia., Norden S; TissuPath, Mount Waverley, VIC, Australia., Ryan A; TissuPath, Mount Waverley, VIC, Australia., Furic L; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Goode DL; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia.; Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Frydenberg M; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Epworth Healthcare, Melbourne, VIC, Australia.; Australian Urology Associates, Melbourne, VIC, Australia.; Department of Surgery, Monash University, Clayton, VIC, Australia.; Department of Urology, Cabrini Institute, Cabrini Health, Melbourne, VIC, Australia., Lawrence MG; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC, Australia.; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Taylor RA; Cancer Research Division, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. renea.taylor@monash.edu.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia. renea.taylor@monash.edu.; Prostate Cancer Research Group, Monash Biomedicine Discovery Institute, Cancer Program, Department of Physiology, Monash University, Clayton, VIC, Australia. renea.taylor@monash.edu.

Publikováno v: Nature communications [Nat Commun] 2021 Aug 19; Vol. 12 (1), pp. 5049. Date of Electronic Publication: 2021 Aug 19.