Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Richards, G.O."'
Knockout technologies provide insights into physiological roles of genes. Studies initiated into endocrinology of heteromeric G protein-coupled receptors included deletion of receptor activity modifying protein-3, an accessory protein that alters lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::34186aee864c19d5bead9693b039178f
Autor:
Zirimwabagabo, J.-O., Jailani, A.B.A., Avgoustou, P., Tozer, M.J., Gibson, K.R., Glossop, P.A., Mills, J.E.J., Porter, R.A., Blaney, P., Wang, N., Skerry, T.M., Richards, G.O., Harrity, J.P.A.
Class B G-protein-coupled receptors (GPCRs) remain an underexploited target for drug development. The calcitonin receptor (CTR) family is particularly challenging, as its receptors are heteromers comprising two distinct components: the calcitonin rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ddfbd0a1ff494e0de7993c3a1c27754a
https://eprints.whiterose.ac.uk/172409/1/acs.jmedchem.0c02191.pdf
https://eprints.whiterose.ac.uk/172409/1/acs.jmedchem.0c02191.pdf
Discovery of a first-in-class potent small molecule antagonist against the adrenomedullin-2 receptor
Autor:
Avgoustou, P., Jailani, A.B.A., Zirimwabagabo, J.-O., Tozer, M.J., Gibson, K.R., Glossop, P.A., Mills, J.E.J., Porter, R.A., Blaney, P., Bungay, P., WANG, N., Shaw, A., Bigos, K.J.A., Holmes, J.L., Warrington, J.I., Skerry, T.M., Harrity, J.P.A., Richards, G.O.
The hormone adrenomedullin has both physiological and pathological roles in biology. As a potent vasodilator, adrenomedullin is critically important in regulation of blood pressure, but it also has several roles in disease, of which its actions in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::777c71de2e7e29c7278e83320d64db56
Akademický článek
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Autor:
Prakash, J., Herlin, M., Kumar, J., Garg, G., Akesson, K.E., Grabowski, P.S., Skerry, T.M., Richards, G.O., McGuigan, F.E.A.
Background and aim\ud The Receptor Activity Modifying Proteins (RAMPs) are a group of accessory proteins, of which there are three in humans, that interact with a number of G-protein coupled receptors (GPCR) and play various roles in regulation of en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::7bac94a6526d1f3b79b6ea5718396b81
https://eprints.whiterose.ac.uk/142983/8/1-s2.0-S2590158319300063-main.pdf
https://eprints.whiterose.ac.uk/142983/8/1-s2.0-S2590158319300063-main.pdf
PURPOSE OF REVIEW: This study is to highlight recent discoveries associated with the role of calcitonin peptide family and their receptors in prostate cancer progression and bone metastasis. \ud \ud RECENT FINDINGS: Studies have linked adrenomedullin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::545261ea173034ca4aa958fdccb31417
Autor:
Weston, C., Lu, J., Li, N., Barkan, K., Richards, G.O., Roberts, D.J., Skerry, T.M., Poyner, D., Pardamwar, M., Reynolds, C.A., Dowell, S.J., Willars, G.B., Ladds, G.
The glucagon and glucagon-like peptide-1 (GLP-1) receptors\ud play important, opposing roles in regulating blood glucose levels.\ud Consequently, these receptors have been identified as targets\ud for novel diabetes treatments. However, drugs acting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::52a6bc113716ba31c971de6922897a45
Akademický článek
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Akademický článek
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Autor:
Richards, G.O.
Publikováno v:
Religion in Education (1941-7268); 1958, Vol. 25 Issue 1, p12-16, 5p
