Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Richard van den Doel"'
Autor:
Pascalina Sarro, Richard van den Doel, Gijs W.K. van Dedem, Rob Moerman, Ian T. Young, Rosanne A Guijt-van Duijn, F. Laugere, Arthur Kroon, Lucas J. van Vliet, Andre Bossche
Publikováno v:
Biotechnology Advances. 21:431-444
Biotechnology today is a well-established paradigm in many areas of human endeavor, such as the pharmaceutical industry, agriculture, management of the environment and many others. Meanwhile, biology is undergoing a spectacular transition: whereas sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e29b379d53f716f710c17febdb054826
https://doi.org/10.1016/s0734-9750(03)00059-4
https://doi.org/10.1016/s0734-9750(03)00059-4
Publikováno v:
Sensors and Actuators A: Physical. 85:384-389
The evaporation process of liquids from sub-nanoliter wells is studied using both optical microscopy and electrical impedance measurement utilizing integrated electrodes. The wells are manufactured on silicon wafers using conventional photolithograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::592d2b5010d386aca0b2f396fb7d1da4
https://doi.org/10.1016/s0924-4247(00)00413-1
https://doi.org/10.1016/s0924-4247(00)00413-1
Publikováno v:
Sensors and Actuators A: Physical. 83:61-66
Miniaturized reactors with volumes of 60 and 540 pl with integrated contact-less liquid volume detectors are fabricated on silicon. Aluminum electrodes are fabricated in the bottom of the reactors and covered with silicon nitride for electrical insul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b2874bb2dff9de4764be334fb039e0c
https://doi.org/10.1016/s0924-4247(00)00288-0
https://doi.org/10.1016/s0924-4247(00)00288-0
Autor:
Wim van Oel, Wolfgang Hoyer, Yuval Garini, Thomas M. Jovin, Richard van den Doel, Guus Liqui Lung, Heidelinde R. C. Dietrich, Ian T. Young
Publikováno v:
SPIE Proceedings.
In previous publications we have shown that we can perform enzymatic reactions in nanoarrays by means of a microarray-reader based on a conventional microscope. In this publication we report on a modification of this system in order to monitor the ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::526ba779771c31e3d1782f89dac70195
https://doi.org/10.1117/12.587493
https://doi.org/10.1117/12.587493
Autor:
N.P. Pham, Michael J. Vellekoop, V.P. Iordanov, Andre Bossche, L. Richard van den Doel, H.R.C. Dietrich, R. Moerman, Bonnie L. Gray, Pasqualina M. Sarro
Publikováno v:
SPIE Proceedings.
This paper explores the use of photo patternable polymers for integrated high-speed screening arrays, where enzyme reactions are monitored in nano liter volume reactors using fluorescence of NADH and photodiode detection. Implementing the array of na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd94d3a7faffb75f9efd77e2f6b94226
https://doi.org/10.1117/12.472071
https://doi.org/10.1117/12.472071
Publikováno v:
SPIE Proceedings.
Yeast - Saccharomyces cerevisiae- is widely used as a model system for other higher eukaryotes, including man. One of the basic fermentation processes in yeast is the glycolytic pathway, which is the conversion of glucose to ethanol and carbon dioxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53d5ee023dc5563ab73c2083dcdf8287
https://doi.org/10.1117/12.472102
https://doi.org/10.1117/12.472102
Autor:
Ian T. Young, Michael J. Vellekoop, L. Richard van den Doel, Lucas J. van Vliet, Kari H. Hjelt
Publikováno v:
SPIE Proceedings.
We are developing a method for high-throughput screening using arrays of `nanowells' built into a silicon substrate. These wells can serve as bioreactors for studying a variety of biochemical reactions such as the enzymatic activity that occurs in ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91ce8bd09e0403cb2b4e7e2298877381
https://doi.org/10.1117/12.427959
https://doi.org/10.1117/12.427959
Autor:
Johannes Frank, S. Picioreanu, Michael J. Vellekoop, L. Richard van den Doel, Pasqualina M. Sarro, Kari H. Hjelt, Johannes P. A. Marijnissen, R. Moerman, G.W.K. van Dedem, Ian T. Young
Publikováno v:
SPIE Proceedings.
Intelligent Molecular Diagnostic Systems (IMDS)- The objective of this multidisciplinary research program is to design and develop an analytical system that is able to measure and interpret concentrations of various analytes which are dispensed on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe15ace97cf3686bb7bb060ad66ba4d2
https://doi.org/10.1117/12.350052
https://doi.org/10.1117/12.350052
Autor:
Lucas J. van Vliet, R. Moerman, Pasqualina M. Sarro, Johannes Frank, S. Picioreanu, Kari H. Hjelt, L. Richard van den Doel, Michael J. Vellekoop, G.W.K. van Dedem, Ian T. Young
Publikováno v:
SPIE Proceedings.
The goal of our TU Delft interfaculty research program is to develop intelligent molecular diagnostic systems (IMDS) that can analyze liquid samples that contain a variety of biochemical compounds such as those associated with fermentation processes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50f74b27cf8ca2394df5e0ec50ac3ef7
https://doi.org/10.1117/12.350059
https://doi.org/10.1117/12.350059
Autor:
Sharareh Moshir, Ian T. Young, Petra Boukamp, Thierry Fest, Mathilde Perrin, Martina Braun, Tony Chih Yuan Chuang, Virginie Mougey, Yuval Garini, Paul Kerr, Richard van den Doel, Bart J. Vermolen, Alice Ya-Chun Chuang, Sabine Mai
Publikováno v:
BMC Biology. 2:12
Background: The observation of multiple genetic markers in situ by optical microscopy and their relevance to the study of three-dimensional (3D) chromosomal organization in the nucleus have been greatly developed in the last decade. These methods are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfbcda6ab77dd60ce7b53571d883d2f3
https://doi.org/10.1186/1741-7007-2-12
https://doi.org/10.1186/1741-7007-2-12