A phase 3 randomized study to evaluate safety and immunogenicity of 20-valent pneumococcal conjugate vaccine in healthy Japanese infants

Autor: Yasunori Ishihara, Mitsuru Fukazawa, Shinya Enomoto, Richard de Solom, Masako Yamaji, Mary Kline, Masakazu Aizawa, Yahong Peng, Osamu Kogawara, Peter C. Giardina, Noor Tamimi, William C. Gruber, Wendy Watson

Publikováno v: International Journal of Infectious Diseases, Vol 141, Iss , Pp 106942- (2024)

Objectives: Safety and immunogenicity evaluation of a 4-dose series with 20-valent pneumococcal conjugate vaccine (PCV20). Methods: This phase 3, double-blind study randomized healthy Japanese infants to receive 4 doses (3 infant doses, 1 toddler dos

Externí odkaz: https://doaj.org/article/e0e45f2660a14988b484febfbc2f4db8

A phase 1 randomized study assessing safety and immunogenicity of two 3-dose regimens of a Clostridium difficile vaccine in healthy older Japanese adults

Autor: Charles Knirsch, Kathrin U. Jansen, Richard de Solom, Masakazu Aizawa, Takuma Yonemura, Masako Yamaji, Megumi Inoue, Chris Webber, Michael W. Pride, William C. Gruber

Publikováno v: Vaccine. 37(19)

Background Clostridium difficile infection (CDI) is a major global cause of nosocomial and community-acquired infections. Despite potentially severe or fatal complications and frequent recurrence, no preventive vaccine is currently available. This ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e408ca42f7f50a1d60da65cb016dd70
https://pubmed.ncbi.nlm.nih.gov/30962095

Safety and Immunogenicity of the BNT162b2 Vaccine Coadministered with Seasonal Inactivated Influenza Vaccine in Adults.

Autor: Murdoch, Louise¹ (AUTHOR), Quan, Karen² (AUTHOR) Karen.Quan@pfizer.com, Baber, James A.² (AUTHOR), Ho, Agnes W. Y.³ (AUTHOR), Zhang, Ying³ (AUTHOR), Xu, Xia³ (AUTHOR), Lu, Claire⁴ (AUTHOR), Cooper, David⁴ (AUTHOR), Koury, Kenneth⁴ (AUTHOR), Lockhart, Stephen P.⁵ (AUTHOR), Anderson, Annaliesa S.⁴ (AUTHOR), Türeci, Özlem⁶ (AUTHOR), Şahin, Uğur⁶ (AUTHOR), Swanson, Kena A.⁴ (AUTHOR), Gruber, William C.⁴ (AUTHOR), Kitchin, Nicholas⁵ (AUTHOR), the C4591030 Clinical Trial Group (AUTHOR), Arya, Mark (AUTHOR), Athan, Eugene (AUTHOR), Blackmore, Timothy (AUTHOR)

Publikováno v: Infectious Diseases & Therapy. Sep2023, Vol. 12 Issue 9, p2241-2258. 18p.

Phase 3 immunogenicity and safety study of a tick-borne encephalitis vaccine in healthy Japanese participants 1 year of age and older.

Autor: Yonekawa M; Ohigesenseino Kodomo Clinic, Sapporo, Hokkaido, Japan. Electronic address: ohige_kodomoclinic@me.com., Watanabe T; Watanabe Pediatric Allergy Clinic, Sapporo, Hokkaido, Japan., Kogawara O; Vaccine Research, Pfizer R&D Japan, Tokyo, Japan., Yoshii C; Vaccine Research, Pfizer R&D Japan, Tokyo, Japan., Yamaji M; Vaccine Research, Pfizer R&D Japan, Tokyo, Japan., Aizawa M; Vaccine Research, Pfizer R&D Japan, Tokyo, Japan., Erber W; Medical Development and Scientific/Clinical Affairs, Pfizer Vaccines, Vienna, Austria., Ito S; Vaccine Medical Affairs, Pfizer Japan Inc, Tokyo, Japan., Jug B; QC Logistics, Pfizer Manufacturing Austria GmbH, Orth an der Donau, Austria., Koelch D; Vaccines Analytical Development, Pfizer, Orth, Austria., de Solom R; Pfizer Australia, Sydney, NSW, Australia., Lockhart SP; Vaccine Research and Development, Pfizer Ltd, Hurley, UK.

Publikováno v: Vaccine [Vaccine] 2024 May 10; Vol. 42 (13), pp. 3180-3189. Date of Electronic Publication: 2024 Apr 12.