Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Richard Yan-Do"'
Autor:
Andrew R. Pepper, Rena Pawlick, Antonio Bruni, John Wink, Yasmin Rafiei, Doug O’Gorman, Richard Yan-Do, Boris Gala-Lopez, Tatsuya Kin, Patrick E. MacDonald, A.M. James Shapiro
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1689-1700 (2017)
Beta-cell replacement therapy is an effective means to restore glucose homeostasis in select humans with autoimmune diabetes. The scarcity of “healthy” human donor pancreata restricts the broader application of this effective curative therapy.
Externí odkaz:
https://doaj.org/article/7a2e5616b5f345c8894e6551fb96b290
Autor:
Xianglin Ji, Peilin Fang, Xi Zhao, Chuanyin Xiong, Qi Yang, Youyang Wan, Richard Yan Do, Zixun Wang, Lin Qi, Linfeng Huang, Wenjun Zhang, Xin Wang, Peng Shi
The importance of genetic or epi-genetic heterogeneity has been increasingly recognized, but it has been challenging to profile intracellular post-transcriptional targets with sufficient throughput and resolution at across large-scale tissue samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::884d8efc6d963c456dc10ea3d494240c
https://doi.org/10.1101/2022.12.11.519542
https://doi.org/10.1101/2022.12.11.519542
Autor:
Peilin Fang, Xianglin Ji, Xi Zhao, Richard Yan‐Do, Youyang Wan, Ying Wang, Yuanting Zhang, Peng Shi
Publikováno v:
Advanced materials (Deerfield Beach, Fla.).
Methylated circulating DNAs (ctDNAs) have recently been reported as a promising biomarker for early cancer diagnostics, but limited tools are currently available for continuous and dynamic profiling of ctDNAs and their methylation levels, especially
Pancreatic islets are highly interconnected structures that produce pulses of insulin and other hormones, maintaining normal homeostasis of glucose and other nutrients. Normal stimulus-secretion and intercellular coupling are essential to regulated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e2e982e7675af813fe4c8d296b6a17
https://doi.org/10.2337/figshare.20775532.v1
https://doi.org/10.2337/figshare.20775532.v1
Pancreatic islets are highly interconnected structures that produce pulses of insulin and other hormones, maintaining normal homeostasis of glucose and other nutrients. Normal stimulus-secretion and intercellular coupling are essential to regulated s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ee8934dad1387e80ff40536f1a90fe7
https://doi.org/10.1101/2021.12.08.471749
https://doi.org/10.1101/2021.12.08.471749
Autor:
Xudong Lin, Tianying Sun, Minghui Tang, Anqi Yang, Richard Yan‐Do, Da Chen, Yaobin Gao, Xin Duan, Ji‐Jung Kai, Feng Wang, Peng Shi
Publikováno v:
Advanced Healthcare Materials. 11:2200304
Upconversion techniques offer all-optical wireless alternatives to modulate targeted neurons in behaving animals, but most existing upconversion-based optogenetic devices show prefixed emission that is used to excite just one channelrhodopsin at a re
Autor:
Tatsuya Kin, Yasmin Rafiei, Doug O’Gorman, Boris Gala-Lopez, A. M. James Shapiro, Antonio Bruni, Patrick E. MacDonald, Rena Pawlick, Richard Yan-Do, John Wink, Andrew R. Pepper
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1689-1700 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Beta-cell replacement therapy is an effective means to restore glucose homeostasis in select humans with autoimmune diabetes. The scarcity of “healthy” human donor pancreata restricts the broader application of this effective curative the
Autor:
Richard Yan-Do, Patrick E. MacDonald
Publikováno v:
Endocrinology. 158(5)
The onset and/or progression of type 2 diabetes (T2D) can be prevented if intervention is early enough. As such, much effort has been placed on the search for indicators predictive of prediabetes and disease onset or progression. An increasing body o
Autor:
Eric Duong, Richard Yan-Do, Stephen Cheley, Xichen Wu, Shara Khan, Austin Bautista, Patrick E. MacDonald, Matthias Braun
Publikováno v:
Diabetologia. 57:2535-2545
There is evidence that ATP acts as an autocrine signal in beta cells but the receptors and pathways involved are incompletely understood. Here we investigate the receptor subtype(s) and mechanism(s) mediating the effects of ATP on human beta cells.We
Autor:
James Lyon, Jocelyn E. Manning Fox, Xiao-Qing Dai, Shara Khan, Eric Duong, Mourad Ferdaoussi, Stephen Cheley, Patrick E. MacDonald, Kunimasa Suzuki, Austin Bautista, Matthias Braun, Xichen Wu, Richard Yan-Do
Publikováno v:
Diabetes. 65(8)
The secretion of insulin from pancreatic islet β-cells is critical for glucose homeostasis. Disrupted insulin secretion underlies almost all forms of diabetes, including the most common form, type 2 diabetes (T2D). The control of insulin secretion i