Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Richard Wombacher"'
Autor:
Aleksandar Salim, Philipp Werther, Georgios N. Hatzopoulos, Luc Reymond, Richard Wombacher, Pierre Gönczy, Kai Johnsson
Publikováno v:
JACS Au, Vol 3, Iss 8, Pp 2247-2256 (2023)
Externí odkaz:
https://doaj.org/article/5e6a37777aa84ef59ba4b48e55b70e93
A dark intermediate in the fluorogenic reaction between tetrazine fluorophores and trans-cyclooctene
Publikováno v:
Biophysical Reports, Vol 2, Iss 4, Pp 100084- (2022)
Fluorogenic labeling via bioorthogonal tetrazine chemistry has proven to be highly successful in fluorescence microscopy of living cells. To date, trans-cyclooctene (TCO) and bicyclonyne have been found to be the most useful substrates for live-cell
Externí odkaz:
https://doaj.org/article/2b7dd35eb1894d079b740e457508206d
Autor:
Philipp Werther, Klaus Yserentant, Felix Braun, Kristin Grußmayer, Vytautas Navikas, Miao Yu, Zhibin Zhang, Michael J. Ziegler, Christoph Mayer, Antoni J. Gralak, Marvin Busch, Weijie Chi, Frank Rominger, Aleksandra Radenovic, Xiaogang Liu, Edward A. Lemke, Tiago Buckup, Dirk-Peter Herten, Richard Wombacher
Publikováno v:
ACS Central Science, Vol 7, Iss 9, Pp 1561-1571 (2021)
Externí odkaz:
https://doaj.org/article/5c0b772560f44f72a5671573bed63344
Autor:
Vytautas Navikas, Samuel M. Leitao, Kristin S. Grussmayer, Adrien Descloux, Barney Drake, Klaus Yserentant, Philipp Werther, Dirk-Peter Herten, Richard Wombacher, Aleksandra Radenovic, Georg E. Fantner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Methods for imaging the 3D cell surface often require physical interaction. Here the authors report the combination of scanning ion conductance microscopy (SICM) and live-cell super-resolution optical fluctuation imaging (SOFI) for the non-invasive t
Externí odkaz:
https://doaj.org/article/8564f2433b224019a49df1f8e9b184c1
Autor:
Dirk Ollech, Tim Pflästerer, Adam Shellard, Chiara Zambarda, Joachim Pius Spatz, Philippe Marcq, Roberto Mayor, Richard Wombacher, Elisabetta Ada Cavalcanti-Adam
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Adherens junctions (AJs) mediate cell-cell adhesion between epithelial cells but tools to study their dynamic regulation are lacking. Here the authors develop an optochemical tool to stimulate the assembly of AJs through addition of a photocleavable
Externí odkaz:
https://doaj.org/article/eedcc41d33c14987b2cfb07669f2953d
Autor:
Dirk Ollech, Tim Pflästerer, Adam Shellard, Chiara Zambarda, Joachim Pius Spatz, Philippe Marcq, Roberto Mayor, Richard Wombacher, Elisabetta Ada Cavalcanti-Adam
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/f7678404b6694a6f8f37c5bb8903fbef
Autor:
Felix Braun, Richard Wombacher, Frank Rominger, Aleksandra Radenovic, Marvin Busch, Philipp Werther, Edward A. Lemke, Antoni J. Gralak, Klaus Yserentant, Weijie Chi, Michael J. Ziegler, Zhibin Zhang, Dirk-Peter Herten, Christoph Mayer, Xiaogang Liu, Kristin S. Grußmayer, Vytautas Navikas, Miao Yu, Tiago Buckup
Publikováno v:
ACS Central Science
ACS Central Science, Vol 7, Iss 9, Pp 1561-1571 (2021)
ACS Central Science, 7(9)
ACS Central Science, Vol 7, Iss 9, Pp 1561-1571 (2021)
ACS Central Science, 7(9)
Small-molecule fluorophores enable the observation of biomolecules in their native context with fluorescence microscopy. Specific labeling via bio-orthogonal tetrazine chemistry combines minimal label size with rapid labeling kinetics. At the same ti
Autor:
Michael J. Ziegler, Klaus Yserentant, Valentin Dunsing, Volker Middel, Antoni J. Gralak, Kaisa Pakari, Jörn Bargstedt, Christoph Kern, Annett Petrich, Salvatore Chiantia, Uwe Strähle, Dirk-Peter Herten, Richard Wombacher
Publikováno v:
Nature chemical biology, 18 (1), 64–69
Nature Chemical Biology
Nature Chemical Biology
Direct control of protein interactions by chemically induced protein proximity holds great potential for both cell and synthetic biology as well as therapeutic applications. Low toxicity, orthogonality and excellent cell permeability are important cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f423bf487699fc2e13f68004bd2f3d8b
https://publikationen.bibliothek.kit.edu/1000143183/147570161
https://publikationen.bibliothek.kit.edu/1000143183/147570161
Autor:
Adrien Descloux, Samuel M. Leitao, Georg E. Fantner, Richard Wombacher, Barney Drake, Klaus Yserentant, Dirk-Peter Herten, Philipp Werther, Aleksandra Radenovic, Kristin S. Grussmayer, Vytautas Navikas
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
High-resolution live-cell imaging is necessary to study complex biological phenomena. Modern fluorescence microscopy methods are increasingly combined with complementary, label-free techniques to put the fluorescence information into the cellular con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bd65f8b8bd0d9f308465de197e6714
https://pubmed.ncbi.nlm.nih.gov/34315910/
https://pubmed.ncbi.nlm.nih.gov/34315910/
Autor:
Richard Wombacher, Felix Braun, Mathis Baalmann, Dirk-Peter Herten, Philipp Werther, Nicolai Kaltwasser, Christoph Popp, Klaus Yserentant
Publikováno v:
Angewandte Chemie (International Ed. in English)
Recent developments in fluorescence microscopy call for novel small‐molecule‐based labels with multiple functionalities to satisfy different experimental requirements. A current limitation in the advancement of live‐cell single‐molecule local