Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Richard Wiger"'
Autor:
Ann-Karin Olsen, Ashild Andreassen, Rajinder Singh, Richard Wiger, Nur Duale, Peter B Farmer, Gunnar Brunborg
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11349 (2010)
BACKGROUND: Spermatozoal DNA damage is associated with poor sperm quality, disturbed embryonic development and early embryonic loss, and some genetic diseases originate from paternal de novo mutations. We previously reported poor repair of bulky DNA-
Externí odkaz:
https://doaj.org/article/fd20ad52553d49ff9f70a3387410d4f4
Autor:
Richard Wiger
Publikováno v:
CRC Handbook of Census Methods for Terrestrial Vertebrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a115d1912c8682baebd6b038143b217a
https://doi.org/10.1201/9781003210320-96
https://doi.org/10.1201/9781003210320-96
Autor:
Richard Wiger, Inger-Lise Steffensen, Ann-Karin Olsen, Åshild Kristine Andreassen, Kiyoji Tanaka
Publikováno v:
Journal of Andrology. 32:541-549
Mice deficient in the xeroderma pigmentosum group A gene (Xpa) exhibit impaired nucleotide excision repair (NER) and are expected to accumulate bulky DNA adducts when subjected to certain compounds (eg, heterocyclic amines). Multiple intestinal neopl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05be618bc19573b36b23aaea45c3a10c
https://doi.org/10.2164/jandrol.110.011916
https://doi.org/10.2164/jandrol.110.011916
Autor:
Anette Krogenæs, Janneche Utne Skaare, Erik Ropstad, Richard Wiger, Irma C. Oskam, Jan Ludvig Lyche, Audun Stien, Ellen Dahl, Torres Sweeney, Ragnar Thomassen
Publikováno v:
Reproduction. 130:731-742
In this study, female goats were orally exposed to PCB126 or PCB153, at 49 ng/kg body weight per day and 98 μg/kg body weight per day respectively, from gestational day 60 until delivery at approximately day 150. Exposure of the offspring continued
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb95e424c7878bc49fb9be696fe7520d
https://doi.org/10.1530/rep.1.00690
https://doi.org/10.1530/rep.1.00690
Publikováno v:
Toxicology and Applied Pharmacology. 207:521-531
Male reproductive health has received considerable attention in recent years. In addition to declining sperm quality, fertility problems and increased incidence of testicular cancer, there is accumulating evidence that genetic damage, in the form of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2548f88b98dd7ccbc6d2bddd639cf5c0
https://doi.org/10.1016/j.taap.2005.01.060
https://doi.org/10.1016/j.taap.2005.01.060
Autor:
Adrian J. Smith, Janneche Utne Skaare, Kjell Andersen Berg, Erik Ropstad, Richard Wiger, Irma C. Oskam, Aage Tverdal
Publikováno v:
Reproductive Toxicology. 19:169-180
This study examined the effects of acute exposure to PCB99 (2,2′,4,4′,5-pentachlorobiphenyl), and PCB153 (2,2′,4,4′5,5′-hexachlorobiphenyl), on spermatogenesis in 8-week-old C57BL6 mice. The mice were randomly allocated to PCB99 and PCB153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a03fa59c32793aa97766a9b86dc6a1
https://doi.org/10.1016/j.reprotox.2004.07.005
https://doi.org/10.1016/j.reprotox.2004.07.005
Publikováno v:
Toxicology Letters. 150:317-323
17 α-Ethinylestradiol (EE) can induce oxidative DNA damage in terms of 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) in rat testicular cells by an apparent estrogen receptor-mediated mechanism. We investigated differential susceptibility to EE in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa8c9bab08ab22182e3907dc080de45
https://doi.org/10.1016/j.toxlet.2004.02.010
https://doi.org/10.1016/j.toxlet.2004.02.010
Autor:
Irma C. Oskam, Andrew E. Derocher, Elisabeth Lie, Stig Larsen, Richard Wiger, Janneche Utne Skaare, Ellen Dahl, Øystein Wiig, Erik Ropstad
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 66:2119-2139
Normal sexual development and subsequent reproductive function are dependent on appropriate testosterone production and action. The regulation of steroid hormones, including androgens, can be influenced by both biological and environmental factors, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ded82cdbf1245623f262b7e78e40527
https://doi.org/10.1080/15287390390211342
https://doi.org/10.1080/15287390390211342
Autor:
Jørn A. Holme, Jan Tore Samuelsen, Magne Refsnes, Per E. Schwarze, E. Morrison, Aksel Bernhoft, Richard Wiger, Marit Låg
Publikováno v:
Cell Biology and Toxicology. 19:53-68
T-2 and HT-2 toxins belong to a group of mycotoxins that are widely encountered as natural contaminants known to elicit toxic responses in hematopoietic cells. In the present study, HL-60 cells were used to characterize the apoptotic effects of T-2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c541d034a9bd9624cb82533cbcb111c6
https://doi.org/10.1023/a:1022069715399
https://doi.org/10.1023/a:1022069715399
Publikováno v:
Molecular Human Reproduction. 7:403-408
We investigated the frequency of spontaneous apoptosis and expression of the Bcl-2 family of proteins during normal spermatogenesis in man. Testicular tissue with both normal morphology and DNA content was obtained from necro-donors and fixed in Boui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76ae7bbdf67283599838b4abfc97ac3
https://doi.org/10.1093/molehr/7.5.403
https://doi.org/10.1093/molehr/7.5.403