Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Richard W. Vachet"'
Autor:
Anya B. Zhong, Isabella H. Muti, Stephen J. Eyles, Richard W. Vachet, Kristen N. Sikora, Cedric E. Bobst, David Calligaris, Sylwia A. Stopka, Jeffery N. Agar, Chin-Lee Wu, Mari A. Mino-Kenudson, Nathalie Y. R. Agar, David C. Christiani, Igor A. Kaltashov, Leo L. Cheng
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The status of metabolomics as a scientific branch has evolved from proof-of-concept to applications in science, particularly in medical research. To comprehensively evaluate disease metabolomics, multiplatform approaches of NMR combining with mass sp
Externí odkaz:
https://doaj.org/article/5cfbe20407d341d4a29f4d0281cf00e6
Autor:
Xianzhi Zhang, Yuanchang Liu, Jeerapat Doungchawee, Laura J. Castellanos-García, Kristen N. Sikora, Taewon Jeon, Ritabrita Goswami, Stefano Fedeli, Aarohi Gupta, Rui Huang, Cristina-Maria Hirschbiegel, Roberto Cao-Milán, Prabin K.D. Majhi, Yagiz Anil Cicek, Liang Liu, D. Joseph Jerry, Richard W. Vachet, Vincent M. Rotello
Publikováno v:
Journal of Controlled Release. 357:31-39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a3872fe89a2a4a27294e3a2c738d4c1
https://doi.org/10.1016/j.jconrel.2023.03.032
https://doi.org/10.1016/j.jconrel.2023.03.032
Autor:
Zachary J. Kirsch, Jeanna M. Blake, Uyen Huynh, Dheeraj K. Agrohia, Catherine Y. Tremblay, Eric M. Graban, Robert C. Vaughan, Richard W. Vachet
Publikováno v:
Analytical Chemistry. 95:7178-7185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdafbd2e67177131b6734714066868c3
https://doi.org/10.1021/acs.analchem.2c05616
https://doi.org/10.1021/acs.analchem.2c05616
Publikováno v:
Journal of the American Society for Mass Spectrometry. 34:82-91
Membrane-associated proteins are important because they mediate interactions between a cell's external and internal environment and they are often targets of therapeutics. Characterizing their structures and binding interactions, however, is challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8f19380fac4c99b6932d570a37085c
https://doi.org/10.1021/jasms.2c00262
https://doi.org/10.1021/jasms.2c00262
Autor:
Stacey Nash, Richard W. Vachet
Publikováno v:
Journal of the American Chemical Society. 144:22128-22139
Proteins can adopt different conformational states that are important for their biological function and, in some cases, can be responsible for their dysfunction. The essential roles that proteins play in biological systems make distinguishing the str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c31adaeb79f0916811183a5665eeb7d
https://doi.org/10.1021/jacs.2c09573
https://doi.org/10.1021/jacs.2c09573
Publikováno v:
ACS Biomater Sci Eng
The delivery of functional proteins to the intracellular space offers tremendous advantages for the development of new therapeutics but is limited by the passage of these large polar biomacromolecules through the cell membrane. Noncovalent polymer-pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd88ac588ade854345b60449b0eccf7b
https://pubmed.ncbi.nlm.nih.gov/35608244
https://pubmed.ncbi.nlm.nih.gov/35608244
Publikováno v:
J Am Soc Mass Spectrom
Characterizing antibody-antigen interactions is necessary for properly developing therapeutic antibodies, understanding their mechanisms of action, and patenting new drug molecules. Here, we demonstrate that hydrogen deuterium exchange (HDX) mass spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1876dbc3515607a3477b686ee8acce
https://doi.org/10.1021/jasms.2c00108
https://doi.org/10.1021/jasms.2c00108
Multisite Labeling of Proteins Using the Ligand-Directed Reactivity of Triggerable Michael Acceptors
Autor:
Myrat Kurbanov, Zachary J. Kirsch, Jithu Krishna, Ranit Dutta, Richard W. Vachet, S. Thayumanavan
Publikováno v:
Bioconjugate Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c440fafa7336b0122ff12adfe4f96a9
https://doi.org/10.1021/acs.bioconjchem.3c00155
https://doi.org/10.1021/acs.bioconjchem.3c00155
Publikováno v:
J Am Soc Mass Spectrom
Covalent labeling mass spectrometry allows for protein structure elucidation via covalent modification and identification of exposed residues. Diethylpyrocarbonate (DEPC) is a commonly used covalent labeling reagent that provides insight into structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24305d8bd10e03c83632e5f8c725b55
https://doi.org/10.1021/jasms.1c00373
https://doi.org/10.1021/jasms.1c00373
