Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Richard W. Tsika"'
Publikováno v:
eLife, Vol 5 (2016)
When unperturbed, somatic stem cells are poised to affect immediate tissue restoration upon trauma. Yet, little is known regarding the mechanistic basis controlling initial and homeostatic ‘scaling’ of stem cell pool sizes relative to their targe
Externí odkaz:
https://doaj.org/article/bc22a392f4d8417d9e13388c12dfdd81
Autor:
Richard W. Tsika, Frank W. Booth, Kevin A. Zwetsloot, Thomas E. Childs, R. Andrew Shanely, Simon J. Lees
Publikováno v:
American Journal of Physiology-Cell Physiology. 297:C1019-C1027
IGF-I increases skeletal muscle mass, but whether IGF-I increases type IIb myosin heavy chain (MyHC) transcriptional activity is not known. C2C12myotubes were cultured with or without IGF-I to determine whether IGF-I increases type IIb MyHC promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d8ed1f501748ec7ffc851d15e26f97
https://doi.org/10.1152/ajpcell.00169.2009
https://doi.org/10.1152/ajpcell.00169.2009
Autor:
Robert J. Kelm, Juan Ji, Richard W. Tsika, Hansjörg Rindt, Gretchen L. Tsika, John J. McCarthy, Kathy L. Schreiber
Publikováno v:
Molecular and Cellular Biology. 27:1531-1543
Adult skeletal muscle retains the capability of transcriptional reprogramming. This attribute is readily observable in the non-weight-bearing (NWB) soleus muscle, which undergoes a slow-to-fast fiber type transition concurrent with decreased beta-myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f546e6847490e970005c02a088be4830
https://doi.org/10.1128/mcb.00629-06
https://doi.org/10.1128/mcb.00629-06
Publikováno v:
Molecular and Cellular Biology. 24:10777-10791
Skeletal muscle is a highly organized tissue that performs the specialized function of force development. In the adult mouse, four major myosin heavy chain (MyHC) isoforms [fast IIb, IIx/d, and IIa and slow type I (β)] are expressed in a manner that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfbdfc6af1d1ec9388c469796bbe488
https://doi.org/10.1128/mcb.24.24.10777-10791.2004
https://doi.org/10.1128/mcb.24.24.10777-10791.2004
Autor:
Juan Ji, Richard W. Tsika, Aijing Zhang, Natalia G. Karasseva, Gretchen L. Tsika, Xiaoqing Mao
Publikováno v:
Molecular and Cellular Biology. 23:5143-5164
In adult mouse skeletal muscle, beta-myosin heavy chain (betaMyHC) gene expression is primarily restricted to slow type I fibers; however, its expression can be induced in fast type II fibers in response to a sustained increase in load-bearing work (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc561af16dc9a2c24fe530298a75b83
https://doi.org/10.1128/mcb.23.15.5143-5164.2003
https://doi.org/10.1128/mcb.23.15.5143-5164.2003
Publikováno v:
American Journal of Physiology-Cell Physiology. 283:C1761-C1775
We examined the functional role of distinct muscle-CAT (MCAT) elements during non-weight-bearing (NWB) regulation of a wild-type 293-base pair β-myosin heavy chain (βMyHC) transgene. Electrophoretic mobility shift assays (EMSA) revealed decreased N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f613c3fc4b5dda2b3cf5f67b481c300
https://doi.org/10.1152/ajpcell.00278.2002
https://doi.org/10.1152/ajpcell.00278.2002
Publikováno v:
Journal of Biological Chemistry. 276:1173-1184
To examine the role of the beta-myosin heavy chain (betaMyHC) distal muscle CAT (MCAT) element in muscle fiber type-specific expression and mechanical overload (MOV) responsiveness, we conducted transgenic and in vitro experiments. In adult transgeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69f39cc477e48ec3536199eda850f28
https://doi.org/10.1074/jbc.m007750200
https://doi.org/10.1074/jbc.m007750200
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 272:R1552-R1561
Non-weight-bearing (NWB) activity [space flight and hindlimb suspension (HS)] results in the loss of soleus muscle mass, a slow-to-fast fiber-type conversion, and decreased beta-myosin heavy chain (beta-MHC) protein and mRNA expression. To identify b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09844cebbc00556ee6c6c862804f2bb7
https://doi.org/10.1152/ajpregu.1997.272.5.r1552
https://doi.org/10.1152/ajpregu.1997.272.5.r1552
Autor:
J. L. Wiedenman, Richard W. Tsika, G. L. Tsika, D. Vyas, L. Gao, K. Sheriff-Carter, I. D. Rivera-Rivera, J. J. McCarthy
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 271:R688-R695
The DNA regulatory element(s) involved in beta-myosin heavy chain (beta-MHC) induction by the physiological stimulus of mechanical overload have not been identified as yet. To delineate regulatory sequences that are required for mechanical overload i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb53c91dcf71c28968d87452795dd05
https://doi.org/10.1152/ajpregu.1996.271.3.r688
https://doi.org/10.1152/ajpregu.1996.271.3.r688
Autor:
L. Gao, K. Sheriff-Carter, I. D. Rivera-Rivera, G. L. Tsika, J. J. McCarthy, Richard W. Tsika, J. L. Wiedenman
Publikováno v:
American Journal of Physiology-Cell Physiology. 271:C690-C699
Mechanical overload leads to hypertrophy, increased type I fiber composition, and beta-myosin heavy chain (beta-MHC) induction in the fast-twitch plantaris muscle. To better understand the mechanism(s) involved in beta-MHC induction, we have examined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02a530c15bfc2b4ded0cd100895909c
https://doi.org/10.1152/ajpcell.1996.271.2.c690
https://doi.org/10.1152/ajpcell.1996.271.2.c690