Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Richard W. Price"'
Autor:
Birgitta Anesten, Henrik Zetterberg, Staffan Nilsson, Bruce J. Brew, Dietmar Fuchs, Richard W. Price, Magnus Gisslén, Aylin Yilmaz
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Blood-brain barrier (BBB) injury is prevalent in patients with HIV-associated dementia (HAD) and is a frequent feature of HIV encephalitis. Signs of BBB damage are also sometimes found in neuroasymptomatic HIV-infected individuals
Externí odkaz:
https://doaj.org/article/9eac7f7027464308ba73d195f4f04f91
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
This short review provides an overview of the interactions of human immunodeficiency virus type 1 (HIV), immune and inflammatory reactions, and CNS injury over the course of infection. Systemic infection is the overall driver of disease and serves as
Externí odkaz:
https://doaj.org/article/5c770c98be0241ccab9c18ea943881e5
Autor:
Da Cheng, Zhenwu Luo, Xiaoyu Fu, Sophie Stephenson, Clara Di Germanio, Philip J. Norris, Dietmar Fuchs, Lishomwa C. Ndhlovu, Quan-zhen Li, Henrik Zetterberg, Magnus Gisslen, Richard W. Price, Shifang Peng, Wei Jiang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The mechanisms of persistent central nervous system (CNS) inflammation in people with HIV (PWH) despite effective antiretroviral therapy (ART) are not fully understood. We have recently shown that plasma anti-CD4 IgGs contribute to poor CD4+
Externí odkaz:
https://doaj.org/article/5aae1f4d2d714f9db84cf5721ad8de34
Autor:
Michael J. Peluso, Cassandra Thanh, Cecilia A. Prator, Louise E. Hogan, Victor M. Arechiga, Sophie Stephenson, Philip J. Norris, Clara Di Germanio, Dietmar Fuchs, Henrik Zetterberg, Steven G. Deeks, Magnus Gisslén, Richard W. Price, Timothy J. Henrich
Publikováno v:
Journal of Virus Eradication, Vol 6, Iss 1, Pp 19-26 (2020)
Objectives: The aim of this study was to assess soluble CD30 (sCD30), a protein that colocalises with HIV-1 RNA and DNA in lymphoid cells and tissues, in cerebrospinal fluid (CSF) as a marker of HIV-1 infection in the central nervous system (CNS). Me
Externí odkaz:
https://doaj.org/article/e72fe490946d41de944dc6da75154a4b
Autor:
Birgitta Anesten, Henrik Zetterberg, Staffan Nilsson, Bruce J. Brew, Dietmar Fuchs, Richard W. Price, Magnus Gisslen, Aylin Yilmaz
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/0f117726600940bf9d3db0eb57c966b5
Autor:
Nithya Srinivas, Sarah Beth Joseph, Kevin Robertson, Laura P. Kincer, Prema Menezes, Lourdes Adamson, Amanda P. Schauer, Kimberly H. Blake, Nicole White, Craig Sykes, Paul Luciw, Joseph J. Eron, Alan Forrest, Richard W. Price, Serena Spudich, Ronald Swanstrom, Angela D.M. Kashuba
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 3, Pp 302-311 (2019)
Sparse data exist on the penetration of antiretrovirals into brain tissue. In this work, we present a framework to use efavirenz (EFV) pharmacokinetic (PK) data in plasma, cerebrospinal fluid (CSF), and brain tissue of eight rhesus macaques to predic
Externí odkaz:
https://doaj.org/article/5ca79d0690d344ad8e6aa2ae8ce87005
Autor:
Magnus Gisslén, Richard W. Price, Ulf Andreasson, Niklas Norgren, Staffan Nilsson, Lars Hagberg, Dietmar Fuchs, Serena Spudich, Kaj Blennow, Henrik Zetterberg
Publikováno v:
EBioMedicine, Vol 3, Iss C, Pp 135-140 (2016)
Background: Cerebrospinal fluid (CSF) neurofilament light chain protein (NFL) is a sensitive marker of neuronal injury in a variety of neurodegenerative conditions, including the CNS dysfunction injury that is common in untreated HIV infection. Howev
Externí odkaz:
https://doaj.org/article/88217842287e4f4497e16ae77a37f9f4
Autor:
Arjet Gega, Michael J. Kozal, Jennifer Chiarella, Evelyn Lee, Julia Peterson, Frederick M. Hecht, Teri Liegler, Elizabeth P. St John, Birgitte B. Simen, Richard W. Price, Serena S. Spudich
Publikováno v:
Journal of Virus Eradication, Vol 1, Iss 4, Pp 264-268 (2015)
Background: Limited data exist comparing viral quasispecies between cerebrospinal fluid (CSF) and plasma compartments during primary HIV infection. Deep sequencing is a new method to examine the HIV plasma and CSF quasispecies. Methods: In this pilot
Externí odkaz:
https://doaj.org/article/0c5ace84b85b4a57b59b502472b43b7d
Autor:
Magnus Gisslén, Richard W. Price, Ulf Andreasson, Niklas Norgren, Staffan Nilsson, Lars Hagberg, Dietmar Fuchs, Serena Spudich, Kaj Blennow, Henrik Zetterberg
Publikováno v:
EBioMedicine, Vol 7, Iss C, Pp 287-288 (2016)
Externí odkaz:
https://doaj.org/article/6b0e98625dda4f3e8f0e304ead307d7b
Autor:
Clara Duran-Castells, Anuska Llano, Ai Kawana-Tachikawa, Anna Prats, Ignacio Martinez-Zalacain, Mie Kobayashi-Ishihara, Bruna Oriol-Tordera, Ruth Peña, Cristina Gálvez, Sandra Silva-Arrieta, Bonaventura Clotet, Eva Riveira-Muñoz, Esther Ballana, Julia G. Prado, Javier Martinez-Picado, Jorge Sanchez, Beatriz Mothe, Dennis Hartigan-O’Connor, Tony Wyss-Coray, Andreas Meyerhans, Magnus Gisslén, Richard W. Price, Carles Soriano-Mas, José Antonio Muñoz-Moreno, Christian Brander, Marta Ruiz-Riol
Publikováno v:
Journal of Virology. 97
The implementation and access to combined antiretroviral treatment (cART) have dramatically improved the quality of life of people living with HIV (PLWH). However, some comorbidities, such as neurological disorders associated with HIV infection still