Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Richard W. Godfrey"'
Publikováno v:
Arthritis & Rheumatism. 31:1421-1428
Tritiated arachidonic acid (3H-AA)-labeled rat synovial fibroblasts stimulated with human recombinant interleukin-1 beta (rIL-1 beta) released incorporated radiolabel in a time-dependent and dose-dependent manner, with labeled prostaglandins represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89cf9953ec24a889c3d8de5ff763b84f
https://doi.org/10.1002/art.1780311112
https://doi.org/10.1002/art.1780311112
Autor:
Don E. Griswold, George Poste, Michael J. DiMartino, J F Newton, Henry M. Sarau, Paul J. Marshall, John G. Gleason, E. F. Webb, Richard W. Godfrey, Nabil Hanna
Publikováno v:
Biochemical Pharmacology. 36:3463-3470
The effects of SK&F 86002 [5-(4-pyridyl)-6 (4-fluorophenyl)-2,3-dihydroimidazo (2,1-b) thiazole] on the generation of eicosanoids in vitro and on inflammatory responses in vivo are described and compared to other non-steroidal anti-inflammatory drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032551642e9769e597bc35ae9d34fa20
https://doi.org/10.1016/0006-2952(87)90327-3
https://doi.org/10.1016/0006-2952(87)90327-3
Publikováno v:
Biochemical and biophysical research communications. 142(1)
Stimulation of [3H]-arachidonic acid labeled human synovial cells with 3.0 X 10(-10)M recombinant interleukin-1 or tumor necrosis factor resulted in the release of incorporated radiolabel (41.1% and 27.7% respectively). Analysis of [3H]-arachidonic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb58065e0681ad65a5a22c0dd49e209
https://pubmed.ncbi.nlm.nih.gov/3028403
https://pubmed.ncbi.nlm.nih.gov/3028403
Publikováno v:
Inflammation. 12(3)
Radiolabeled human peripheral blood monocytes released [3H]arachidonic acid upon challenge with the calcium ionophore A23187 (10 microM), or f-Met-Leu-Phe (FMLP, 1 microM). Chromatographic analysis of [3H]arachidonic acid labeled phospholipids showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f044dfabc296730a576e66d9be4ca6a
https://pubmed.ncbi.nlm.nih.gov/2458317
https://pubmed.ncbi.nlm.nih.gov/2458317
Publikováno v:
Journal of cellular physiology. 131(3)
Receptor-ligand interaction in mononuclear phagocytes is intimately linked to alterations in membrane phospholipids and release of arachidonic acid (AA). In addition, synthesis of bioactive lipids from released AA can result in further modification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81336305666db91247d4279ae6488140
https://pubmed.ncbi.nlm.nih.gov/2439518
https://pubmed.ncbi.nlm.nih.gov/2439518