Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Richard W. Fuller"'
Autor:
Brice Wilson, Ning Li, Juliana Martinez Fiesco, Masoumeh Dalilian, Dongdong Wang, Sarath Senadeera, Lin Du, Richard W. Fuller, Rohan Shah, Emily A. Smith, Ekaterina I. Goncharova, John A. Beutler, Tanja Grkovic, Ping Zhang, Barry R. O’Keefe
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.
Autor:
Curtis J. Henrich, Emily A. Smith, Carole A. Bewley, Chang-Kwon Kim, Kirk R. Gustafson, Deborah K. Morrison, Dongdong Wang, David E. Durrant, Richard W. Fuller, Heidi R. Bokesch
Publikováno v:
J Nat Prod
Two new cyclic depsipeptides named swinhopeptolides A (1) and B (2), have been isolated from the marine sponge Theonella swinhoei cf. verrucosa, collected from Papua New Guinea. They each contain 11 diverse amino acid resudues and 13-carbon polyketid
Autor:
James B. McMahon, Karlyne M. Reilly, Curtis J. Henrich, Laura K. Cartner, Kirk R. Gustafson, Richard W. Fuller, Anthony Rizzo, Jennifer A. Wilson
Publikováno v:
Journal of Natural Products. 78:2776-2781
A high-throughput screening assay for modulators of Trp53/NF1 mutant astrocytoma cell growth was adapted for use with natural product extracts and applied to a novel collection of prefractionated/partially purified extracts. Screening 68 427 samples
Autor:
Kentaro Takada, Jennifer A. Wilson, James B. McMahon, Naoya Oku, Kirk R. Gustafson, Lewis K. Pannell, Richard W. Fuller, Megan L. Peach
Publikováno v:
Journal of the American Chemical Society. 132:10278-10285
Enigmazole A (1), a novel phosphate-containing macrolide, was isolated from a Papua New Guinea collection of the marine sponge Cinachyrella enigmatica. The structure of 1, including the absolute stereochemistry at all eight chiral centers, was determ
Autor:
Jennifer A. Wilson, Kirk R. Gustafson, Richard W. Fuller, James A. Kelley, Laura K. Cartner, Curtis J. Henrich, Tawnya C. McKee, Heidi R. Bokesch, James B. McMahon
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3848-3850
Five new naphthopyrones (1-5) along with the known compounds TMC-256A1, 5,8-dihydroxy-6-methoxy-2-propyl-4H-naphtho[2,3-b]pyran-4-one, TMC-256C1, comaparvin, 6-methoxy comaparvin, and 6-methoxycomaparvin 5-methyl ether (7-11) were isolated from crino
Autor:
Michael R. Boyd, Tanya R. Johnson, John H. Cardellina, Neil A. Durso, William R. Gamble, Chandra K. Westergaard, Ernest Hamel, Dan L. Sackett, Richard W. Fuller
Publikováno v:
Bioorganic & Medicinal Chemistry. 7:1611-1615
Chemical and biological investigations of extracts from the sponge genus Auletta and two collections of Siphonochalina sp. have shown these organisms to be producers of the potent hemiasterlin class of antitumor agents. In addition to the previously
Publikováno v:
Natural Product Letters. 8:169-172
A new kaurane diterpene was isolated and identified as the major HIV-inhibitory constituent of the aqueous extract of fruits of a Xylopia sp. plant. Analysis of spectral data revealed the structure of the compound, xylopinic acid (1), a new diastereo
Autor:
Jurek J, Alvarado-Lindner B, Menez E, McGuire M, Gray Gn, Richard W. Fuller, Jon Clardy, Steiner, Cardellina Jh nd, Paul J. Scheuer
Publikováno v:
Journal of Medicinal Chemistry. 37:4407-4411
Ten halogenated monoterpenes (2-6 and 8-12) related to the novel anti- tumor compound halomon (1) or to the carbocyclic analog 7 have been isolated from different geographic collections of the red alga, Portie- ria hornemannii. Structures were assign
Publikováno v:
European Journal of Pharmacology. 264:301-306
The effect of beta 2-adrenoceptor agonists, salmeterol and salbutamol on thromboxane B2 release from human airway macrophages and peripheral blood monocytes has been examined. Salbutamol (0.1-100 microM) had no inhibitory effect on the release of thr
Autor:
John H. Cardellina, Djaja D. Soejarto, Richard W. Fuller, Marian R. Kadushin, Heidi R. Bokesch, Michael R. Boyd, Kirk R. Gustafson
Publikováno v:
Tetrahedron Letters. 35:5821-5824
During a survey of latex samples of Calophyllum teysmannii for anti-HIV coumarins (calanolide A, costatolide), calanone (5), an unprecedented benzoyl substituted coumarin, was isolated and its structure determined by spectroscopic analyses. The known