Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Richard W. Doughty"'
Publikováno v:
Veterinary dermatologyREFERENCES. 33(6)
Publikováno v:
Comparative Clinical Pathology. 15:263-266
A splenic marginal zone lymphoma was diagnosed in a female European harvest mouse (Micromys minutus) that presented clinically with poor body condition and abdominal swelling. On palpation, a mass in the cranial abdomen was identified. The owner elec
Publikováno v:
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 65(5)
Contrast-induced nephropathy (CIN) remains a serious complication in patients exposed to iodinated X-ray contrast media (ICM). Animal models of CIN are useful to further understand the mechanisms involved, identify novel biomarkers and evaluate poten
Publikováno v:
Renal failure. 33(4)
Nephrotoxicity, associated with the administration of iodinated X-ray contrast media (ICM), continues to be a major side effect in a significant number of vulnerable patients undergoing diagnostic X-ray imaging procedures. The molecular mechanisms un
Autor:
Christina Rada, Leonardo A. Meza-Zepeda, Gaute Nesse, Jon K. Laerdahl, Liv Kleppa, Arne Klungland, Richard W. Doughty, Cesilie G. Castellanos, Michael S. Neuberger, Trine J. Meza, Elisabeth Larsen, Guro Flor Lien
Publikováno v:
Cancer research. 68(12)
Flap endonuclease 1 (FEN1) processes Okazaki fragments in lagging strand DNA synthesis, and FEN1 is involved in several DNA repair pathways. The interaction of FEN1 with the proliferating cell nuclear antigen (PCNA) processivity factor is central to
Autor:
Peter Leander, Chun-Ming Chai, Torsten Almén, Rikard Pehrson, Jonas Björk, Klaes Golman, Derek Grant, Richard W. Doughty, Ulf Nyman, Barbara Elmståhl
Publikováno v:
Radiology. 247(1)
To prospectively compare nephrotoxicity and radiodensity of plasma hyperosmotic gadolinium chelates (attenuation-osmotic ratio of 1:1) with those of plasma iso-osmotic iodine-based contrast media (attenuation-osmotic ratio of 3:1 or 6:1) after renal
Autor:
Peter Leander, Torsten Almén, Ulf Nyman, Barbara Elmståhl, Jonas Björk, Chun-Ming Chai, Derek Grant, Richard W. Doughty
Publikováno v:
Acta radiologica (Stockholm, Sweden : 1987). 48(10)
Background: Gadolinium contrast media (Gd-CM) are regarded as non-nephrotoxic or considerably less nephrotoxic than iodine contrast media (I-CM), and have therefore come to be used as a substitute for I-CM in patients with renal insufficiency in a va
Autor:
Vivi Talstad, Hans E. Krokan, Line M. Nordstrand, Jeanette Ringvoll, Nina-Beate Liabakk, Knut H. Lauritzen, Alexandra Bjørk, Per Arne Aas, Richard W. Doughty, Karen Reite, Arne Klungland, Cathrine Broberg Vågbø, Pål Ø. Falnes
Publikováno v:
The EMBO journal. 25(10)
Two human homologs of the Escherichia coli AlkB protein, denoted hABH2 and hABH3, were recently shown to directly reverse 1-methyladenine (1meA) and 3-methylcytosine (3meC) damages in DNA. We demonstrate that mice lacking functional mABH2 or mABH3 ge