Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Richard W. Deed"'
Publikováno v:
Molecular and Cellular Biology. 21:524-533
The Id subfamily of helix-loop-helix (HLH) proteins plays a fundamental role in the regulation of cellular proliferation and differentiation. The major mechanism by which Id proteins are thought to inhibit differentiation is through interaction with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873b030d8e806c4e19544fd7d6f5b18c
https://doi.org/10.1128/mcb.21.2.524-533.2001
https://doi.org/10.1128/mcb.21.2.524-533.2001
Publikováno v:
Trends in Cell Biology. 8:58-65
Id helix-loop-helix proteins function at a general level as positive regulators of cell growth and as negative regulators of cell differentiation. They act as dominant-negative antagonists of other helix-loop-helix transcription factors, which drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08aa720794ef435bb91a7187e229cb68
https://doi.org/10.1016/s0962-8924(98)80013-5
https://doi.org/10.1016/s0962-8924(98)80013-5
Publikováno v:
FEBS Letters. 393:113-116
The Id family of helix-loop-helix proteins function as negative regulators of DNA binding, basic helix-loop-helix proteins in the regulation of cell growth and differentiation. We report here on the identification of a 17 kDa variant of the 14 kDa Id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7e16f964cbec7af3fc93171eab82cb
https://doi.org/10.1016/0014-5793(96)00868-x
https://doi.org/10.1016/0014-5793(96)00868-x
Publikováno v:
Gene. 151:309-314
The helix-loop-helix (HLH) family of transcription factors plays a central role in the regulation of cell growth, differentiation and tumourigenesis. Members of the Id (inhibitor of DNA binding) class of these nuclear proteins are able to heterodimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4dc17d19f1066757519f2a110d7ce5
https://doi.org/10.1016/0378-1119(94)90676-9
https://doi.org/10.1016/0378-1119(94)90676-9
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1219:160-162
We have determined the cDNA sequence encoding a 154 amino acid human Id-1 helix-loop-helix protein. Comparison with the amino acid sequences of human and mouse Id-2 and Id-3 proteins, reveals conservation/divergence of several residues in the helix-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3c93a61613bd80f33f52a3971789c4
https://doi.org/10.1016/0167-4781(94)90261-5
https://doi.org/10.1016/0167-4781(94)90261-5
Autor:
Isabelle Godin, Jeff Cooke, T Michael Dexter, Richard W Deed, Krisztina M. Zsebo, Christopher Wylie
Publikováno v:
Nature. 352:807-809
Mutations at the steel (sl) and dominant white spotting (W) loci in the mouse affect primordial germ cells (PGC), melanoblasts and haemopoietic stem cells. The W gene encodes a cell-surface receptor of the tyrosine kinase family, the proto-oncogene c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0142dc9cf2d195b50b48ca2d03ffc240
https://doi.org/10.1038/352807a0
https://doi.org/10.1038/352807a0
Publikováno v:
The EMBO journal. 18(4)
The Id subfamily of helix-loop-helix (HLH) proteins plays a fundamental role in the regulation of cellular proliferation and differentiation. Id proteins are thought to inhibit differentiation mainly through interaction with other HLH proteins and by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222cd6cad56015ae649172088227278b
https://pubmed.ncbi.nlm.nih.gov/10022839
https://pubmed.ncbi.nlm.nih.gov/10022839
Autor:
Richard W. Deed, Julia M. H. Smith, Paul Rooney, Shant Kumar, Patricia Kumar, John D. Norton, Anthony J. Freemont
The degradation products of hyaluronan are known to stimulate endothelial-cell proliferation and to promote neovascularization associated with angiogenesis, whilst native high-molecular-weight hyaluronan is inhibitory to these processes. To investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bc8ffbe024b2019ebc4353d198299e
http://e-space.mmu.ac.uk/13356/
http://e-space.mmu.ac.uk/13356/
Autor:
Richard W. Deed, Tohru Hirose, John J. Murphy, Zhi-Qiang Ning, John D. Norton, Joshua S. Newton
The protein kinase C activator bryostatin induces differentiation and antagonizes the effects of tumour-promoting phorbol esters in a number of different cell types. We show here that bryostatin preferentially inhibits phorbol 12-myristate 13-acetate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268dc52b7d930797c079ea3acd849f52
https://europepmc.org/articles/PMC1217735/
https://europepmc.org/articles/PMC1217735/
Publikováno v:
The Journal of biological chemistry. 271(39)
Members of the Id family of helix-loop-helix proteins function as negative regulators of DNA binding, E protein, helix-loop-helix transcription factors in the control of cell growth, differentiation, and development. By using transient transfection a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b51a15c7d83d40b5cef96b6ab29fa34
https://pubmed.ncbi.nlm.nih.gov/8798572
https://pubmed.ncbi.nlm.nih.gov/8798572