Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Richard W. Decker"'
Autor:
Richard W. Decker, Robin L. Bliss, Yongjian Lu, Daniel R Parkin, Gloria A. Niehans, Danuta Malejka-Giganti, Kristen K. Bennett
Publikováno v:
European Journal of Cancer Prevention. 16:130-141
This study examined whether suppression of mammary gland carcinogenesis elicited by low doses of tamoxifen (TAM) can be enhanced by concomitant treatment of rats with indole-3-carbinol (I3C), a component of cruciferous vegetables and a dietary supple
Publikováno v:
Chemical Research in Toxicology. 5:520-527
Chemical or enzymatic oxidations of the carcinogen N-hydroxy-N-(2- fluorenyl)benzamide (N-OH-2-FBA) were investigated under the conditions facilitating one-electron oxidation or oxidative cleavage of N-hydroxy-N-(2-fluorenyl)acetamide (N-OH-2-FAA). H
Autor:
Danuta Malejka-Giganti, Gloria A. Niehans, Robin L. Bliss, Mona I. Churchwell, Richard W. Decker, Daniel R Parkin, Frederick A. Beland
Publikováno v:
International journal of cancer. 122(9)
Environmental pollution with nitroaromatic compounds may pose health hazards. We have examined the tumorigenicity in female Sprague-Dawley rats of 2,7-dinitrofluorene (2,7-diNF) and 9-oxo-2,7-diNF administered by intraperitoneal (i.p.) and oral route
Publikováno v:
Chemical research in toxicology. 13(8)
Nitrofluorenes and C-9-oxidized nitrofluorenes are widespread environmental genotoxins which may be relevant for breast cancer on the basis of their carcinogenicities, particularly of 2, 7-dinitrofluorene (2,7-diNF), for the rat mammary gland. Since
Publikováno v:
Proceedings of the twenty-first SIGCSE technical symposium on Computer science education - SIGCSE '90.
Publikováno v:
Biochemical Pharmacology. 32:3335-3344
The effects of treating lactating rats with 3-methylcholanthrene (3-MC) or β-naphthoflavone (β-NF) (three i.p. injections of 20 or 40 mg compound/kg of body weight) on hepatic microsomal enzymes of their suckling young were examined. This treatment
Autor:
Richard W. Decker, Nobuko S. Mizuno
Publikováno v:
Biochemical Pharmacology. 25:2643-2647
5-(3-Methyl-1-triazeno)imidazole-4-carboxamide (NSC-407347, MTIC), an active intermediate in the metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388, DTIC), was investigated for its effect on DNA. When [ 3 H]MTIC was added to
Autor:
Dean W. Stebbins, Richard W. Decker
Publikováno v:
Journal of Applied Physics. 26:1004-1006
The DuBridge variation of the Fowler theory of photoelectric emission was utilized to determine the work function of the borides of La, Pr, and Nd. The work functions of LaB6, PrB6, and NdB6 were found to be 2.74 ev, 3.12 ev, and 4.57 ev, respectivel
Publikováno v:
Carcinogenesis. 6(1)
We determined ring- and N-hydroxylations of a systemic mammary gland carcinogen, N-2-fluorenylacetamide (2-FAA), by microsomal fractions of liver and mammary gland of female rats and the effects of in vivo and/or in vitro modifiers of these oxidation
Publikováno v:
Biochemical pharmacology. 24(5)
All experiments were performed in the absence of light. A 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (MIC) concentration of less than 10 −4 M had no effect on cell growth of L cells. At higher concentrations, the cells were inhibited to levels