Zobrazeno 1 - 10
of 509
pro vyhledávání: '"Richard W. Compans"'
Autor:
Ying Liu, Ling Ye, Fang Lin, Yasmine Gomaa, David Flyer, Ricardo Carrion, Jean L. Patterson, Mark R. Prausnitz, Gale Smith, Gregory Glenn, Hua Wu, Richard W. Compans, Chinglai Yang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/ff2b5d4e8873422293eb5e1c62295876
Autor:
Jacob T. Beaver, Lisa K. Mills, Dominika Swieboda, Nadia Lelutiu, Edward S. Esser, Olivia Q. Antao, Eugenia Scountzou, Dahnide T. Williams, Nikolaos Papaioannou, Elizabeth Q. Littauer, Andrey Romanyuk, Richard W. Compans, Mark R. Prausnitz, Ioanna Skountzou
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 9, Pp 2072-2091 (2020)
Zika virus (ZIKV) causes moderate to severe neuro-ocular sequelae, with symptoms ranging from conjunctivitis to Guillain-Barré Syndrome (GBS). Despite the international threat ZIKV poses, no licensed vaccine exists. As ZIKV and DENV are closely rela
Externí odkaz:
https://doaj.org/article/6807a5c17b694e71b3ad090e91e910f2
Autor:
Elena V. Vassilieva, Song Li, Heorhiy Korniychuk, Dahnide M. Taylor, Shelly Wang, Mark R. Prausnitz, Richard W. Compans
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Current strategies for improving protective response to influenza vaccines during immunosenescence do not adequately protect individuals over 65 years of age. Here, we used an aged mouse model to investigate the potential of co-delivery of influenza
Externí odkaz:
https://doaj.org/article/7e1492b6ae5f4dfda6599132b47970e0
Autor:
Ying Liu, Zhiyuan Wen, Ricardo Carrion, Jerritt Nunneley, Hilary Staples, Anysha Ticer, Jean L. Patterson, Richard W. Compans, Ling Ye, Chinglai Yang
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Ebolavirus (EBOV) infection in humans causes severe hemorrhagic fevers with high mortality rates that range from 30 to 80% as shown in different outbreaks. Thus the development of safe and efficacious EBOV vaccines remains an important goal for biome
Externí odkaz:
https://doaj.org/article/baecee747b1d491da5b2ca3bff93b862
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
There is an urgent need to improve protective responses to influenza vaccination in the elderly population, which is at especially high risk for adverse outcomes from influenza infection. Currently available inactivated vaccines provide limited prote
Externí odkaz:
https://doaj.org/article/a7b783073dee49e28ac6a26a8387ec20
Autor:
Lei Deng, Teena Mohan, Timothy Z. Chang, Gilbert X. Gonzalez, Ye Wang, Young-Man Kwon, Sang-Moo Kang, Richard W. Compans, Julie A. Champion, Bao-Zhong Wang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Relatively well conserved domains of influenza A virus (IAV) proteins are potential candidates for the development of a universal IAV vaccine. Here, Deng et al. combine two such conserved antigens (M2e and HA stalk) in a double-layered protein nanopa
Externí odkaz:
https://doaj.org/article/1e1b7e376b26409f8f98647986ff3a30
Autor:
E. Stein Esser, Joanna A. Pulit-Penaloza, Haripriya Kalluri, Devin McAllister, Elena V. Vassilieva, Elizabeth Q. Littauer, Nadia Lelutiu, Mark R. Prausnitz, Richard W. Compans, Ioanna Skountzou
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Influenza virus causes life-threatening infections in pregnant women and their newborns. Immunization during pregnancy is the most effective means of preventing maternal and infant mortality/morbidity; however, influenza vaccination rates of
Externí odkaz:
https://doaj.org/article/bee56125b1cf4f40b60481bcbec9c6ab
Autor:
Florian Krammer, Ron A. M. Fouchier, Maryna C. Eichelberger, Richard J. Webby, Kathryn Shaw-Saliba, Hongquan Wan, Patrick C. Wilson, Richard W. Compans, Ioanna Skountzou, Arnold S. Monto
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Neuraminidase is one of the two surface glycoproteins of influenza A and B viruses. It has enzymatic activity that cleaves terminal sialic acid from glycans, and that activity is essential at several points in the virus life cycle. While neu
Externí odkaz:
https://doaj.org/article/3f64edeb94884879b50fdc42041b2317
Publikováno v:
Viruses, Vol 6, Iss 5, Pp 1974-1991 (2014)
Due to frequent viral antigenic change, current influenza vaccines need to be re-formulated annually to match the circulating strains for battling seasonal influenza epidemics. These vaccines are also ineffective in preventing occasional outbreaks of
Externí odkaz:
https://doaj.org/article/19c9d74046504e2399598158d2759719
Autor:
Min-Chul Kim, Ki-Hye Kim, Jeong Woo Lee, Yu-Na Lee, Hyo-Jick Choi, Yu-Jin Jung, Yu-Jin Kim, Richard W. Compans, Mark R. Prausnitz, Sang-Moo Kang
Publikováno v:
Pharmaceutics, Vol 11, Iss 4, p 188 (2019)
It is a high priority to develop a simple and effective delivery method for a cross-protective influenza vaccine. We investigated skin immunization by microneedle (MN) patch with human influenza split vaccine and virus-like particles containing heter
Externí odkaz:
https://doaj.org/article/b4346c49ca294d3ba1942d5393c3ceb2