Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Richard W. Carthew"'
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105097- (2022)
Summary: Cell fate decisions can be envisioned as bifurcating dynamical systems, and the decision that Drosophila cells make during sensory organ differentiation has been described as such. We extended these studies by focusing on the Senseless prote
Externí odkaz:
https://doaj.org/article/33411d8b5d3c4deeb700b5492feedfcf
Autor:
Victoria A. Church, Sigal Pressman, Mamiko Isaji, Mary Truscott, Nihal Terzi Cizmecioglu, Stephen Buratowski, Maxim V. Frolov, Richard W. Carthew
Publikováno v:
Cell Reports, Vol 20, Iss 13, Pp 3123-3134 (2017)
The cellular abundance of mature microRNAs (miRNAs) is dictated by the efficiency of nuclear processing of primary miRNA transcripts (pri-miRNAs) into pre-miRNA intermediates. The Microprocessor complex of Drosha and DGCR8 carries this out, but it ha
Externí odkaz:
https://doaj.org/article/18f0c1c2733240598accbdfcb27f21a8
Publikováno v:
eLife, Vol 12 (2024)
The atypical cadherins Fat and Dachsous (Ds) signal through the Hippo pathway to regulate growth of numerous organs, including the Drosophila wing. Here, we find that Ds-Fat signaling tunes a unique feature of cell proliferation found to control the
Externí odkaz:
https://doaj.org/article/f3f076d6d63242369e49f9839afc670c
Autor:
Joao Trindade Marques, Ji-Ping Wang, Xiaohong Wang, Karla Pollyanna Vieira de Oliveira, Catherine Gao, Eric Roberto Guimaraes Rocha Aguiar, Nadereh Jafari, Richard W. Carthew
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/229d0339a81d438ba178203a9f7d2b1b
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 8 (2011)
Externí odkaz:
https://doaj.org/article/26629adef1b9413e9c422eed8718e259
Autor:
Sebastian M. Bernasek, Suzy SJ Hur, Nicolás Peláez-Restrepo, Jean-François Boisclair Lachance, Rachael Bakker, Heliodoro Tejedor Navarro, Nicelio Sanchez-Luege, Luís A. N. Amaral, Neda Bagheri, Ilaria Rebay, Richard W. Carthew
Cells must reliably respond to changes in transcription factor levels in order to execute cell state transitions in the correct time and place. These transitions are typically thought to be triggered by changes in the absolute nuclear concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b72da4abd3ccadad21ae2223afac274f
https://resolver.caltech.edu/CaltechAUTHORS:20230613-155503094
https://resolver.caltech.edu/CaltechAUTHORS:20230613-155503094
Autor:
Richard W. Carthew
Publikováno v:
Trends Genet
It is recognized that cell metabolism is tightly connected to other cellular processes such as regulation of gene expression. Metabolic pathways not only provide the precursor molecules necessary for gene expression, but they also provide ATP, the pr
Autor:
Joseph Q Nguyen, Richard W. Carthew, Shelby A. Blythe, Yong Jae Kwon, Kevin G. Nyberg, Greg J. Beitel
Publikováno v:
Fly. 14:34-48
Genome editing via homology-directed repair (HDR) has made possible precise and deliberate modifications to gene sequences. CRISPR/Cas9-mediated HDR is the simplest means to carry this out. However...
Autor:
Gokay Yamankurt, Joseph Q Nguyen, Robert J. Stawicki, Chad A. Mirkin, Richard W. Carthew, Diana M. Posadas
Publikováno v:
Proc Natl Acad Sci U S A
Spherical nucleic acids (SNAs) are nanostructures formed by chemically conjugating short linear strands of oligonucleotides to a nanoparticle template. When made with modified small interfering RNA (siRNA) duplexes, SNAs act as single-entity transfec
Autor:
Kevin G. Nyberg, Richard W. Carthew
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071625408
Methods in Molecular Biology ISBN: 9781071625408
The CRISPR/Cas9 system provides the means to make precise and purposeful modifications to the genome via homology-directed repair (HDR). In Drosophila, a wide variety of tools provide flexibility to achieve these ends. Here, we detail a method to gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290da187bc37d212961e87920c58fa2b
https://europepmc.org/articles/PMC10027364/
https://europepmc.org/articles/PMC10027364/