Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Richard W. Clarke"'
Autor:
Bo Larsen, Roberto Hofmann, Ines S Camacho, Richard W Clarke, J Clark Lagarias, Alex R Jones, Alexander M Jones
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002303 (2023)
Optogenetic actuators have revolutionized the resolution at which biological processes can be controlled. In plants, deployment of optogenetics is challenging due to the need for these light-responsive systems to function in the context of horticultu
Externí odkaz:
https://doaj.org/article/39aacb4e36e749e690c1989b9f0c5cc7
Autor:
Bo Larsen, Roberto Hofmann, Ines S Camacho, Richard W Clarke, J Clark Lagarias, Alex R Jones, Alexander M Jones
Publikováno v:
BioRxiv
bioRxiv
bioRxiv
Optogenetic actuators have revolutionized the resolution at which we can assert control over biological processes in living systems. In plants, deployment of optogenetics is challenging due to the need for these light-responsive systems to maintain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad93f122c8c9ee91e44d24df10002755
Autor:
Richard W. Clarke
There are three regimes of cell membrane interaction with glass: Tight and loose adhesion, separated by repulsion. Explicitly including hydration, this paper evaluates the pressure between the surfaces as functions of distance for ion correlation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2267460c12a81ba60560fcd342aa521e
http://arxiv.org/abs/2103.05125
http://arxiv.org/abs/2103.05125
Autor:
Richard W. Clarke
Publikováno v:
ACS Infectious Diseases. 1:403-415
This paper discusses physical and structural aspects of the mechanisms herpes simplex virus (HSV) uses for membrane fusion. Calculations show that herpes simplex virus glycoprotein D has such avidity for its receptors that it can hold the virion agai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d28f389fdc4069e537325bac5bc6ae8
https://doi.org/10.1021/acsinfecdis.5b00059
https://doi.org/10.1021/acsinfecdis.5b00059
Autor:
Nicholas Johnson, Alexander Zhukov, Owen Richards, Victor P. Ostanin, Richard W. Clarke, David Klenerman
Publikováno v:
Journal of the American Chemical Society. 135:322-329
There is an intrinsic repulsion between glass and cell surfaces that allows noninvasive scanning ion conductance microscopy (SICM) of cells and which must be overcome in order to form the gigaseals used for patch clamping investigations of ion channe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8524431fe25a4b50ba4ae130f2ffba2a
https://doi.org/10.1021/ja3094586
https://doi.org/10.1021/ja3094586
Autor:
Alexander Zhukov, Kirill E. Volynski, Cleo L. Bishop, Richard W. Clarke, David Klenerman, Eleanor J. Tyler, Owen Richards, Pavel Novák, Anna Drews, Marife Cano-Jaimez
Publikováno v:
Soft Matter
Directly examining subcellular mechanics whilst avoiding excessive strain of a live cell requires the precise control of light stress on very small areas, which is fundamentally difficult. Here we use a glass nanopipet out of contact with the plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7d6bf7d630a2348cae6aa39cd8f123
https://www.repository.cam.ac.uk/handle/1810/260849
https://www.repository.cam.ac.uk/handle/1810/260849
Autor:
John R. James, Simon J. Davis, David Klenerman, David L. Sleep, Richard W. Clarke, Samuel S. White, Adam M. Johansen, Paul Dunne, William J. Fitzgerald
The T cell receptor (TCR) expressed on most T cells is a protein complex consisting of TCRαβ heterodimers that bind antigen and cluster of differentiation (CD) 3εδ, εγ, and ζζ dimers that initiate signaling. A long-standing controversy concer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e55a7be25b5acddb50f3e287b6cec913
https://ora.ox.ac.uk/objects/uuid:08e39039-d341-4889-9e3a-a4dc00fffcac
https://ora.ox.ac.uk/objects/uuid:08e39039-d341-4889-9e3a-a4dc00fffcac
Autor:
Samuel I. A. Cohen, Paul Dunne, Massimo Sandal, Francesco A. Aprile, Allen Yuyin Chen, David Klenerman, Richard W. Clarke, Tuomas P. J. Knowles, Andrey Y. Abramov, Christopher M. Dobson, Nunilo Cremades, Carlos W. Bertoncini, Emma Deas, Angel Orte, Nicholas W. Wood
Publikováno v:
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
instname
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
We are grateful to Francisco Mateo and Priyanka Narayan for their helpful comments and discussions. N.C. is the recipient of a Human Frontier Science Program Long-term Fellowship (LT000795/2009). S.I.A.C. is supported by a Schiff Foundation Scholarsh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912fdf0136411d239ee5e24a4e7e2448
Autor:
Sarah Meehan, Mark R. Wilson, David Klenerman, Richard W. Clarke, Benedetta Bolognesi, Kristina A. Ganzinger, Christopher M. Dobson, Angel Orte, Priyanka Narayan, Sharon C. Hook
Publikováno v:
Nature Structural & Molecular Biology. 19:79-83
In recent genome-wide association studies, the extracellular chaperone protein, clusterin, has been identified as a newly-discovered risk factor in Alzheimer's disease. We have examined the interactions between human clusterin and the Alzheimer's dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb4f451b14d848411ec180c4276ee6f
https://doi.org/10.1038/nsmb.2191
https://doi.org/10.1038/nsmb.2191
Autor:
Babak Babakinejad, Pavel Novák, David Klenerman, Richard W. Clarke, Yasufumi Takahashi, Julia Gorelik, Andrew Shevchuk, Yuri E. Korchev, Michele Miragoli
Publikováno v:
Nanomedicine. 6:565-575
Cells naturally operate on the nanoscale level, with molecules combining together to form complex molecular machines, which can work together to enable normal cell function or go wrong as in the case of many diseases. Visualizing these key processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6732cc2112875f11269cd6d583b495d
https://doi.org/10.2217/nnm.10.154
https://doi.org/10.2217/nnm.10.154