Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Richard W Hardy"'
Autor:
Tamanash Bhattacharya, Liewei Yan, John M Crawford, Hani Zaher, Irene L G Newton, Richard W Hardy
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010393 (2022)
Arthropod endosymbiont Wolbachia pipientis is part of a global biocontrol strategy to reduce the replication of mosquito-borne RNA viruses such as alphaviruses. We previously demonstrated the importance of a host cytosine methyltransferase, DNMT2, in
Externí odkaz:
https://doaj.org/article/b70c77d65c204192ab9c647fbe723090
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008513 (2020)
The ability of the endosymbiont Wolbachia pipientis to restrict RNA viruses is presently being leveraged to curb global transmission of arbovirus-induced diseases. Past studies have shown that virus replication is limited early in arthropod cells col
Externí odkaz:
https://doaj.org/article/1830499542bd4f9784a686909cd1de9e
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238254 (2020)
The identification of host / pathogen interactions is essential to both understanding the molecular biology of infection and developing rational intervention strategies to overcome disease. Alphaviruses, such as Sindbis virus, Chikungunya virus, and
Externí odkaz:
https://doaj.org/article/7f4470a7507640759e82171549fa6155
Autor:
Kevin J Sokoloski, Lauren M Nease, Nicholas A May, Natasha N Gebhart, Claire E Jones, Thomas E Morrison, Richard W Hardy
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006473 (2017)
Alphaviruses are arthropod-borne viruses that represent a significant threat to public health at a global level. While the formation of alphaviral nucleocapsid cores, consisting of cargo nucleic acid and the viral capsid protein, is an essential mole
Externí odkaz:
https://doaj.org/article/9be5cebb7ebd43c7a2706b30daf0c1f6
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006427 (2017)
Wolbachia pipientis is an intracellular endosymbiont known to confer host resistance against RNA viruses in insects. However, the causal mechanism underlying this antiviral defense remains poorly understood. To this end, we have established a robust
Externí odkaz:
https://doaj.org/article/92c7701d510c4e31b715245a314f97f0
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9, p e1000582 (2009)
Alphaviruses are RNA viruses transmitted between vertebrate hosts by arthropod vectors, primarily mosquitoes. How arthropods counteract alphaviruses or viruses per se is not very well understood. Drosophila melanogaster is a powerful model system for
Externí odkaz:
https://doaj.org/article/4e73b32220af49a181a8bece5e4fd797
Autor:
Michael E. Sparks, Raman Bansal, Joshua B. Benoit, Michael B. Blackburn, Hsu Chao, Mengyao Chen, Sammy Cheng, Christopher Childers, Huyen Dinh, Harsha Vardhan Doddapaneni, Shannon Dugan, Elena N. Elpidina, David W. Farrow, Markus Friedrich, Richard A. Gibbs, Brantley Hall, Yi Han, Richard W. Hardy, Christopher J. Holmes, Daniel S. T. Hughes, Panagiotis Ioannidis, Alys M. Cheatle Jarvela, J. Spencer Johnston, Jeffery W. Jones, Brent A. Kronmiller, Faith Kung, Sandra L. Lee, Alexander G. Martynov, Patrick Masterson, Florian Maumus, Monica Munoz-Torres, Shwetha C. Murali, Terence D. Murphy, Donna M. Muzny, David R. Nelson, Brenda Oppert, Kristen A. Panfilio, Débora Pires Paula, Leslie Pick, Monica F. Poelchau, Jiaxin Qu, Katie Reding, Joshua H. Rhoades, Adelaide Rhodes, Stephen Richards, Rose Richter, Hugh M. Robertson, Andrew J. Rosendale, Zhijian Jake Tu, Arun S. Velamuri, Robert M. Waterhouse, Matthew T. Weirauch, Jackson T. Wells, John H. Werren, Kim C. Worley, Evgeny M. Zdobnov, Dawn E. Gundersen-Rindal
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-26 (2020)
Abstract Background Halyomorpha halys (Stål), the brown marmorated stink bug, is a highly invasive insect species due in part to its exceptionally high levels of polyphagy. This species is also a nuisance due to overwintering in human-made structure
Externí odkaz:
https://doaj.org/article/783db796caef466d842f6cda6cced9e2
Autor:
Kaylee J. Watson, Robin E. Bromley, Benjamin C. Sparklin, Mark T. Gasser, Tamanash Bhattacharya, Jarrett F. Lebov, Tyonna Tyson, Laura E. Teigen, Karen T. Graf, Michelle Michalski, Vincent M. Bruno, Amelia R. I. Lindsey, Richard W. Hardy, Irene L. G. Newton, Julie C. Dunning Hotopp
Publikováno v:
bioRxiv
RNA modifications, such as methylation, can be detected with Oxford Nanopore Technologies direct RNA sequencing. One commonly used tool for detecting 5-methylcytosine (m5C) modifications is Tombo, which uses an “Alternative Model” to detect putat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44d68b759287b1362e5d410a15e7e8b
https://europepmc.org/articles/PMC10187288/
https://europepmc.org/articles/PMC10187288/
Publikováno v:
Viruses; Volume 14; Issue 12; Pages: 2606
Alphaviruses must interact efficiently with two distinct host environments in order to replicate and transmit between vertebrate and mosquito hosts. Some host-origin-dependent differences in virus particle composition that appear to facilitate the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f78987b788df762fc11482968f7c49e5
https://pubmed.ncbi.nlm.nih.gov/36560610
https://pubmed.ncbi.nlm.nih.gov/36560610
Publikováno v:
Viruses
Eukaryotic nucleic acid methyltransferase (MTase) proteins are essential mediators of epigenetic and epitranscriptomic regulation. DNMT2 belongs to a large, conserved family of DNA MTases found in many organisms, including holometabolous insects such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f5b66c5a9eaa14d40dde2e25762dbbb
https://pubmed.ncbi.nlm.nih.gov/34452330
https://pubmed.ncbi.nlm.nih.gov/34452330