Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Richard W Hardy"'
Publikováno v:
Viruses, Vol 15, Iss 8, p 1685 (2023)
Arboviruses are defined by their ability to replicate in both mosquito vectors and mammalian hosts. There is good evidence that arboviruses “prime” their progeny for infection of the next host, such as via differential glycosylation of their oute
Externí odkaz:
https://doaj.org/article/1fd97fc6cab84cc286dfbeaf34a80397
Autor:
Tamanash Bhattacharya, Liewei Yan, John M Crawford, Hani Zaher, Irene L G Newton, Richard W Hardy
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010393 (2022)
Arthropod endosymbiont Wolbachia pipientis is part of a global biocontrol strategy to reduce the replication of mosquito-borne RNA viruses such as alphaviruses. We previously demonstrated the importance of a host cytosine methyltransferase, DNMT2, in
Externí odkaz:
https://doaj.org/article/b70c77d65c204192ab9c647fbe723090
Autor:
Michael E. Sparks, Raman Bansal, Joshua B. Benoit, Michael B. Blackburn, Hsu Chao, Mengyao Chen, Sammy Cheng, Christopher Childers, Huyen Dinh, Harsha Vardhan Doddapaneni, Shannon Dugan, Elena N. Elpidina, David W. Farrow, Markus Friedrich, Richard A. Gibbs, Brantley Hall, Yi Han, Richard W. Hardy, Christopher J. Holmes, Daniel S. T. Hughes, Panagiotis Ioannidis, Alys M. Cheatle Jarvela, J. Spencer Johnston, Jeffery W. Jones, Brent A. Kronmiller, Faith Kung, Sandra L. Lee, Alexander G. Martynov, Patrick Masterson, Florian Maumus, Monica Munoz-Torres, Shwetha C. Murali, Terence D. Murphy, Donna M. Muzny, David R. Nelson, Brenda Oppert, Kristen A. Panfilio, Débora Pires Paula, Leslie Pick, Monica F. Poelchau, Jiaxin Qu, Katie Reding, Joshua H. Rhoades, Adelaide Rhodes, Stephen Richards, Rose Richter, Hugh M. Robertson, Andrew J. Rosendale, Zhijian Jake Tu, Arun S. Velamuri, Robert M. Waterhouse, Matthew T. Weirauch, Jackson T. Wells, John H. Werren, Kim C. Worley, Evgeny M. Zdobnov, Dawn E. Gundersen-Rindal
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-26 (2020)
Abstract Background Halyomorpha halys (Stål), the brown marmorated stink bug, is a highly invasive insect species due in part to its exceptionally high levels of polyphagy. This species is also a nuisance due to overwintering in human-made structure
Externí odkaz:
https://doaj.org/article/783db796caef466d842f6cda6cced9e2
Publikováno v:
Viruses, Vol 14, Iss 12, p 2606 (2022)
Alphaviruses must interact efficiently with two distinct host environments in order to replicate and transmit between vertebrate and mosquito hosts. Some host-origin-dependent differences in virus particle composition that appear to facilitate the tr
Externí odkaz:
https://doaj.org/article/5b8b5bc910e7409f84f9e8c559a81814
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Recently developed arbovirus control strategies leverage the symbiotic bacterium WolbachiaWolbachia
Externí odkaz:
https://doaj.org/article/b68ca18e2fa34ce19b9937115c2c6cea
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008513 (2020)
The ability of the endosymbiont Wolbachia pipientis to restrict RNA viruses is presently being leveraged to curb global transmission of arbovirus-induced diseases. Past studies have shown that virus replication is limited early in arthropod cells col
Externí odkaz:
https://doaj.org/article/1830499542bd4f9784a686909cd1de9e
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238254 (2020)
The identification of host / pathogen interactions is essential to both understanding the molecular biology of infection and developing rational intervention strategies to overcome disease. Alphaviruses, such as Sindbis virus, Chikungunya virus, and
Externí odkaz:
https://doaj.org/article/7f4470a7507640759e82171549fa6155
Publikováno v:
Viruses, Vol 13, Iss 8, p 1464 (2021)
Eukaryotic nucleic acid methyltransferase (MTase) proteins are essential mediators of epigenetic and epitranscriptomic regulation. DNMT2 belongs to a large, conserved family of DNA MTases found in many organisms, including holometabolous insects such
Externí odkaz:
https://doaj.org/article/65b7850f0d784b27b5441232a92e0c48
Autor:
Kaylee J. Watson, Robin E. Bromley, Benjamin C. Sparklin, Mark T. Gasser, Tamanash Bhattacharya, Jarrett F. Lebov, Tyonna Tyson, Laura E. Teigen, Karen T. Graf, Michelle Michalski, Vincent M. Bruno, Amelia R. I. Lindsey, Richard W. Hardy, Irene L. G. Newton, Julie C. Dunning Hotopp
Publikováno v:
bioRxiv
RNA modifications, such as methylation, can be detected with Oxford Nanopore Technologies direct RNA sequencing. One commonly used tool for detecting 5-methylcytosine (m5C) modifications is Tombo, which uses an “Alternative Model” to detect putat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44d68b759287b1362e5d410a15e7e8b
https://europepmc.org/articles/PMC10187288/
https://europepmc.org/articles/PMC10187288/
Autor:
Kevin J Sokoloski, Lauren M Nease, Nicholas A May, Natasha N Gebhart, Claire E Jones, Thomas E Morrison, Richard W Hardy
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006473 (2017)
Alphaviruses are arthropod-borne viruses that represent a significant threat to public health at a global level. While the formation of alphaviral nucleocapsid cores, consisting of cargo nucleic acid and the viral capsid protein, is an essential mole
Externí odkaz:
https://doaj.org/article/9be5cebb7ebd43c7a2706b30daf0c1f6