Zobrazeno 1 - 10
of 306
pro vyhledávání: '"Richard W, Price"'
Autor:
Birgitta Anesten, Henrik Zetterberg, Staffan Nilsson, Bruce J. Brew, Dietmar Fuchs, Richard W. Price, Magnus Gisslén, Aylin Yilmaz
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Blood-brain barrier (BBB) injury is prevalent in patients with HIV-associated dementia (HAD) and is a frequent feature of HIV encephalitis. Signs of BBB damage are also sometimes found in neuroasymptomatic HIV-infected individuals
Externí odkaz:
https://doaj.org/article/9eac7f7027464308ba73d195f4f04f91
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
This short review provides an overview of the interactions of human immunodeficiency virus type 1 (HIV), immune and inflammatory reactions, and CNS injury over the course of infection. Systemic infection is the overall driver of disease and serves as
Externí odkaz:
https://doaj.org/article/5c770c98be0241ccab9c18ea943881e5
Autor:
Michael J. Peluso, Cassandra Thanh, Cecilia A. Prator, Louise E. Hogan, Victor M. Arechiga, Sophie Stephenson, Philip J. Norris, Clara Di Germanio, Dietmar Fuchs, Henrik Zetterberg, Steven G. Deeks, Magnus Gisslén, Richard W. Price, Timothy J. Henrich
Publikováno v:
Journal of Virus Eradication, Vol 6, Iss 1, Pp 19-26 (2020)
Objectives: The aim of this study was to assess soluble CD30 (sCD30), a protein that colocalises with HIV-1 RNA and DNA in lymphoid cells and tissues, in cerebrospinal fluid (CSF) as a marker of HIV-1 infection in the central nervous system (CNS). Me
Externí odkaz:
https://doaj.org/article/e72fe490946d41de944dc6da75154a4b
Autor:
Da Cheng, Zhenwu Luo, Xiaoyu Fu, Sophie Stephenson, Clara Di Germanio, Philip J. Norris, Dietmar Fuchs, Lishomwa C. Ndhlovu, Quan-zhen Li, Henrik Zetterberg, Magnus Gisslen, Richard W. Price, Shifang Peng, Wei Jiang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The mechanisms of persistent central nervous system (CNS) inflammation in people with HIV (PWH) despite effective antiretroviral therapy (ART) are not fully understood. We have recently shown that plasma anti-CD4 IgGs contribute to poor CD4+
Externí odkaz:
https://doaj.org/article/5aae1f4d2d714f9db84cf5721ad8de34
Autor:
Nithya Srinivas, Sarah Beth Joseph, Kevin Robertson, Laura P. Kincer, Prema Menezes, Lourdes Adamson, Amanda P. Schauer, Kimberly H. Blake, Nicole White, Craig Sykes, Paul Luciw, Joseph J. Eron, Alan Forrest, Richard W. Price, Serena Spudich, Ronald Swanstrom, Angela D.M. Kashuba
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 3, Pp 302-311 (2019)
Sparse data exist on the penetration of antiretrovirals into brain tissue. In this work, we present a framework to use efavirenz (EFV) pharmacokinetic (PK) data in plasma, cerebrospinal fluid (CSF), and brain tissue of eight rhesus macaques to predic
Externí odkaz:
https://doaj.org/article/5ca79d0690d344ad8e6aa2ae8ce87005
Autor:
Magnus Gisslen, Sheila M Keating, Serena Spudich, Victor Arechiga, Sophie Stephenson, Henrik Zetterberg, Clara Di Germanio, Kaj Blennow, Dietmar Fuchs, Lars Hagberg, Philip J Norris, Julia Peterson, Barbara L Shacklett, Constantin T Yiannoutsos, Richard W Price
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250987 (2021)
ObjectiveTo characterize the evolution of central nervous system (CNS) inflammation in HIV-1 infection applying a panel of cerebrospinal fluid (CSF) inflammatory biomarkers to grouped subjects representing a broad spectrum of systemic HIV-1 immune su
Externí odkaz:
https://doaj.org/article/2ec0545adb214b17b48bc2f6ac37006b
Autor:
Birgitta Anesten, Henrik Zetterberg, Staffan Nilsson, Bruce J. Brew, Dietmar Fuchs, Richard W. Price, Magnus Gisslen, Aylin Yilmaz
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/0f117726600940bf9d3db0eb57c966b5
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236162 (2020)
HIV cerebrospinal fluid (CSF) escape is defined by a concentration of HIV-1 RNA in CSF above the lower limit of quantification of the employed assay and equal to or greater than the plasma HIV-1 RNA level in the presence of treatment-related plasma v
Externí odkaz:
https://doaj.org/article/22544cec33e1421583998eafe3552cc1
Autor:
Linn Hermansson, Aylin Yilmaz, Richard W Price, Staffan Nilsson, Scott McCallister, Tariro Makadzange, Moupali Das, Henrik Zetterberg, Kaj Blennow, Magnus Gisslen
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226276 (2019)
BackgroundBecause tenofovir alafenamide (TAF) leads to significantly lower plasma tenofovir concentrations than tenofovir disoproxil fumarate (TDF) and is a stronger substrate for P-glycoprotein (P-gp) than TDF, TAF could lead to decreased central ne
Externí odkaz:
https://doaj.org/article/441244adb4e84ebeb9067f07d79d284a
Publikováno v:
Acta Neurologica Scandinavica. 146:56-60
Although clinical examinations, neuroimaging, and cerebrospinal fluid analyses are the most important ways to evaluate the impact of HIV infection on the brain and in diagnosis of opportunistic infections, several blood biomarkers including HIV RNA c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3887f3d4804cc360cb14634cbd6a5e79
https://doi.org/10.1111/ane.13629
https://doi.org/10.1111/ane.13629