Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Richard Vonder Embse"'
Autor:
Lawson Jon P, Sastry A. Kunda, Pieter D. de Koning, Richard Vonder Embse, Lorraine Murtagh, Wei Kong
Publikováno v:
Organic Process Research & Development. 15:1046-1051
A convergent six-step process for the synthesis of PF-04191834 (1), a potent and selective 5-lipoxygenase inhibitor, has been developed and used to deliver over 20 kg of API. The process uses the same bond-forming steps as the initial medicinal chemi