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pro vyhledávání: '"Richard Vernell"'
Autor:
Daniel Levi, Esther Hulleman, Kristian Helin, Richard Vernell, M Quarto, Riccardo Rodriguez y Baena, Giacomo Masserdotti, Maria Capra, Elena Colli, Paolo Gaetani, Johan M. Kros, Patrizia Tunici, Gaetano Finocchiaro
Publikováno v:
Journal of Cellular and Molecular Medicine, 13(1), 136-146. Wiley-Blackwell Publishing Ltd
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine
Glioblastoma multiforme (GBM), the highest-grade glioma, is the most frequent tumour of the brain with a very poor prognosis and limited therapeutic options. Although little is known about the molecular mechanisms that underlie glioblastoma formation
Publikováno v:
Journal of Biological Chemistry. 278:46124-46137
Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of human cancer. The core members of this pathway include the tumor suppressor protein, pRB, which through binding to a number of cellular proteins, most notably members of the E2
Autor:
Elena Vigo, M. Cristina Moroni, Adrian P. Bracken, Kristian Helin, Jonathan D. Oliner, Elena Prosperini, Fred Christians, Richard Vernell, Heiko Muller, Emanuela Grassilli
Publikováno v:
Genesdevelopment. 15(3)
The retinoblastoma protein (pRB) and its two relatives, p107 and p130, regulate development and cell proliferation in part by inhibiting the activity of E2F-regulated promoters. We have used high-density oligonucleotide arrays to identify genes in wh