Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Richard V. Lee"'
Autor:
Oliver Nakano-Baker, Hanson Fong, Shalabh Shukla, Richard V. Lee, Le Cai, Dennis Godin, Tatum Hennig, Siddharth Rath, Igor Novosselov, Sami Dogan, Mehmet Sarikaya, J. Devin MacKenzie
Publikováno v:
Biosensors and Bioelectronics. 229:115237
Publikováno v:
ACS applied materialsinterfaces.
Nucleic acid biomarkers hold great potential as key indicators for the diagnosis and monitoring of diseases. Herein we design and implement bifunctional chimeric biomolecules composed of a solid-binding peptide (SBP) domain that specifically adsorbs
Autor:
Thomas Möller, James S. Strosnider, Jasmine Shen, Jonathan R. Weinstein, Shahani Noor, Richard V. Lee, Ashley McDonough, Ryan Dodge, Gwenn A. Garden, Stephanie Davidson
Publikováno v:
Glia
Ischemic preconditioning (IPC) is an experimental phenomenon in which a sub-threshold ischemic insult applied to the brain reduces damage caused by a subsequent more severe ischemic episode. Identifying key molecular and cellular mediators of IPC wil
Publikováno v:
Neurochemical Research. 42:2625-2638
Microglia, the resident immune cells of the CNS, are primary regulators of the neuroimmune response to injury. Type I interferons (IFNs), including the IFNαs and IFNβ, are key cytokines in the innate immune system. Their activity is implicated in t
Publikováno v:
Chest. 158:A947
Autor:
Davin Gong, Jonathan R. Weinstein, Jamie R. Colman, Thu Le, Richard V. Lee, Margaret A. Hamner, Bruce R. Ransom, Zucheng Ye
Publikováno v:
The Journal of Neuroscience. 35:15599-15611
Ischemic preconditioning (IPC) is a robust neuroprotective phenomenon whereby brief ischemic exposure confers tolerance to a subsequent ischemic challenge. IPC has not been studied selectively in CNS white matter (WM), although stroke frequently invo
Autor:
Michael Iorga, Thomas Möller, Jessica L.H. Phillips, Jonathan R. Weinstein, Ashley McDonough, Chungeun Lee, Shahani Noor, Richard V. Lee, Thu Le, Sean C. Murphy
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(34)
Innate immune signaling is important in the pathophysiology of ischemia/reperfusion (stroke)-induced injury and recovery. Several lines of evidence support a central role for microglia in these processes. Recent work has identified Toll-like receptor
Autor:
Jonathan R. Weinstein, Hunter Phillips, Richard V. Lee, Patricia Tanzi, Kevin C. Cain, Juliane Schulze, Dannielle Zierath, Kyra J. Becker, Dean Shibata
Publikováno v:
NeuroReport. 25:580-584
Acute ischemic stroke (AIS) induces profound alterations in both systemic and central nervous system (CNS) immune responses [1]. In the periphery, these changes include robust increases in plasma concentrations of pro-inflammatory markers such as C-r
Publikováno v:
Neuroreport
Thrombin is a multifunctional serine proteinase that induces a variety of responses from neural cells by cleavage of proteinase-activated receptors (PARs) including PAR1 and PAR4. Thrombin/PAR signaling has been implicated in the neuroinflammatory re