Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Richard Tizard"'
Publikováno v:
Mammalian Genome. 9:114-118
MRC OX-2 is a rat type I membrane glycoprotein and a member of the immunoglobulin gene superfamily that has recently been shown to be able to costimulate murine T cell proliferation (Borriello et al. J. Immunol, 158, 4548, 1997). We now report the ge
Autor:
Richard L. Cate, Jian Min Deng, Neal G. Copeland, Richard R. Behringer, Yuji Mishina, Bhavani G. Pathak, Richard Tizard, Nancy A. Jenkins
Publikováno v:
Biochemical and Biophysical Research Communications. 237:741-746
We have determined the sequence and structure of the mouse Mullerian-inhibiting substance (MIS) type II receptor gene. Sequence comparisons demonstrate that the mouse, rat, rabbit, and human MIS type II receptors are highly conserved. The mouse MIS t
Autor:
R. B. Pepinsky, Paul Carmillo, G. Jaworski, Richard L. Cate, H. Wei, L. Walus, Adrian Whitty, Stephen D. Robinson, Chris Ehrenfels, Catherine Hession, Richard Tizard, D. Worley, Michele Sanicola
Publikováno v:
Proceedings of the National Academy of Sciences. 94:6238-6243
Glial cell line-derived neurotrophic factor (GDNF)-dependent activation of the tyrosine kinase receptor RET is necessary for kidney and enteric neuron development, and mutations in RET are associated with human diseases. Activation of RET by GDNF has
Publikováno v:
Biochemical and Biophysical Research Communications. 216:170-176
cDNA clones representing a small (0.8 kb) form of murine mucosal addressin cell adhesion molecule-1 (MAdCAM-1) mRNA were obtained and sequenced. The sequence was identical to the published 1.6 kb murine MAdCAM-1 cDNA sequence, except that 432 nucleot
Autor:
Eric S. Day, Glenn T. Miller, Michael Karpusas, Laurelee Osborn, Stefan C. Meuer, Richard Tizard, Paula S. Hochman
Publikováno v:
The Journal of Experimental Medicine
Efficient activation and regulation of the cellular immune response requires engagement of T cell accessory molecules as well as the antigen-specific T cell receptor. The lymphocyte function-associated antigen (LFA) 3 (CD58)/CD2 accessory pathway, on
Autor:
Barbara P. Wallner, Catherine Hession, Alexis Z. Frey, Jessica Jahngen-Hodge, Allen Taylor, Casilda V. Mura, Richard Tizard, Antoinette Zuliani
Publikováno v:
Biochemistry. 32:9296-9301
Aminopeptidases catalyze the hydrolysis of amino acid residues from the amino terminus of peptide substrates. Leucine aminopeptidase (LAP) from bovine lens is the best characterized aminopeptidase and the only LAP for which the amino acid sequence wa
Autor:
Barbara P. Wallner, Sarah A. Bixler, Richard Tizard, Werner Meier, Paula S. Hochman, Margaret D. Rosa, Glenn T. Miller
Publikováno v:
The Journal of Experimental Medicine
Accessory cell surface molecules, such as T cell antigen CD2 and its ligand lymphocyte function-associated antigen 3 (LFA-3; CD58), are critical costimulatory pathways for optimal T cell activation in response to antigens. Interaction of CD2 with cel
Autor:
Richard A. Fisher, Richard Tizard, Linda C. Burkly, David D. Ho, Yunzhen Cao, Ruth I. Connor, John P. Moore
Publikováno v:
AIDS Research and Human Retroviruses. 9:529-539
Two sCD4-resistant, primary viruses (P-08 and P-17) were compared with two sCD4-sensitive, T cell line-adapted variants (C-08 and C-17) for their biochemical responses to sCD4. At 37 degrees C, neither primary virus shed gp120 within 8 hr at sCD4 con
Publikováno v:
Journal of Biological Chemistry. 268:8835-8841
Vascular cell adhesion molecule-1 (VCAM1) is a member of the immunoglobulin (Ig) superfamily which interacts with the integrin very late antigen-4 (VLA4). The VCAM1/VLA4 interaction mediates both adhesion and signal transduction and is thought to pla
Autor:
J DeMarinis, Robert A. Fisher, S Turner, Richard Tizard, R B Pepinsky, J Zullo, Robert T. Schooley
Publikováno v:
Proceedings of the National Academy of Sciences. 89:1335-1339
Recombinant soluble CD4 (rsCD4) has potent antiviral activity against cell line-adapted isolates of the human immunodeficiency virus type 1 (HIV-1) but low activity toward HIV-1 primary isolates from patients. A simple hypothesis proposed to explain