Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Richard Telljohann"'
Publikováno v:
Heliyon, Vol 9, Iss 1, Pp e12708- (2023)
Background: Each heartbeat is initiated in the sinoatrial node (SAN), and although a recent study (GSE130710) using single nucleus RNA-seq had discovered different populations of cell types within SAN tissue, the distinct potential functions of these
Externí odkaz:
https://doaj.org/article/f8b73796d09746ed971850cff7203e36
Autor:
Kirill V Tarasov, Khalid Chakir, Daniel R Riordon, Alexey E Lyashkov, Ismayil Ahmet, Maria Grazia Perino, Allwin Jennifa Silvester, Jing Zhang, Mingyi Wang, Yevgeniya O Lukyanenko, Jia-Hua Qu, Miguel Calvo-Rubio Barrera, Magdalena Juhaszova, Yelena S Tarasova, Bruce Ziman, Richard Telljohann, Vikas Kumar, Mark Ranek, John Lammons, Rostislav Bychkov, Rafael de Cabo, Seungho Jun, Gizem Keceli, Ashish Gupta, Dongmei Yang, Miguel A Aon, Luigi Adamo, Christopher H Morrell, Walter Otu, Cameron Carroll, Shane Chambers, Nazareno Paolocci, Thanh Huynh, Karel Pacak, Robert Weiss, Loren Field, Steven J Sollott, Edward G Lakatta
Publikováno v:
eLife, Vol 11 (2022)
Adult (3 month) mice with cardiac-specific overexpression of adenylyl cyclase (AC) type VIII (TGAC8) adapt to an increased cAMP-induced cardiac workload (~30% increases in heart rate, ejection fraction and cardiac output) for up to a year without sig
Externí odkaz:
https://doaj.org/article/14634285f8224aeeb9edfd895e31e4f8
Autor:
Leng Ni, Lijuan Liu, Wanqu Zhu, Richard Telljohann, Jing Zhang, Robert E. Monticone, Kimberly R. McGraw, Changwei Liu, Christopher H. Morrell, Pablo Garrido‐Gil, Jose Luis Labandeira‐Garcia, Edward G. Lakatta, Mingyi Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 17 (2022)
Background Age‐associated aortic remodeling includes a marked increase in intimal medial thickness (IMT), associated with signs of inflammation. Although aortic wall milk fat globule–epidermal growth factor VIII (MFG‐E8) increases with age, and
Externí odkaz:
https://doaj.org/article/bf073e5d078f47adae6b593d9d3cd4ae
Autor:
Mark A. Hutchinson, Han-Sol Park, Kimberly J. Zanotti, Juan Alvarez-Gonzalez, Jing Zhang, Li Zhang, Richard Telljohann, Mingyi Wang, Edward G. Lakatta, Patricia J. Gearhart, Robert W. Maul
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Current models stipulate that B cells and antibodies function during atherosclerosis in two distinct ways based on antibody isotype, where IgM is protective and IgG is inflammatory. To examine this model, we generated ApoE-/- Aid-/- mice, which are u
Externí odkaz:
https://doaj.org/article/bb200d6a373c44d08ca54786ef48d485
Autor:
Mingyi Wang, Li Zhang, Wanqu Zhu, Jing Zhang, Soo Hyuk Kim, Yushi Wang, Leng Ni, Richard Telljohann, Robert E. Monticone, Kimberly McGraw, Lijuan Liu, Rafael de Cabo, Edward G. Lakatta
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 18 (2018)
Background Aging exponentially increases the incidence of morbidity and mortality of quintessential cardiovascular disease mainly due to arterial proinflammatory shifts at the molecular, cellular, and tissue levels within the arterial wall. Calorie r
Externí odkaz:
https://doaj.org/article/1cb3608c3ec6469ea847c976e5e863a8
Autor:
Mingyi Wang, Gaia Spinetti, Robert E Monticone, Jing Zhang, James Wu, Liqun Jiang, Benjamin Khazan, Richard Telljohann, Edward G Lakatta
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16653 (2011)
The coincidence of vascular smooth muscle cells (VSMC) infiltration and collagen deposition within a diffusely thickened intima is a salient feature of central arterial wall inflammation that accompanies advancing age. However, the molecular mechanis
Externí odkaz:
https://doaj.org/article/54822c705bb14872b812f6c993923643
Autor:
Liqun Jiang, Mingyi Wang, Jing Zhang, Robert E Monticone, Richard Telljohann, Gaia Spinetti, Gianfranco Pintus, Edward G Lakatta
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2231 (2008)
Angiotensin II (Ang II) signaling, including matrix metalloproteinase type II (MMP2) activation, has been linked to an age-associated increase in migration capacity of vascular smooth muscle cells (VSMC), and to other proinflammatory features of arte
Externí odkaz:
https://doaj.org/article/be042aa504684cbeb751765d6ba31770
Autor:
Kirill V Tarasov, Khalid Chakir, Daniel R Riordon, Alexey E Lyashkov, Ismayil Ahmet, Maria Grazia Perino, Allwin Jennifa Silvester, Jing Zhang, Mingyi Wang, Yevgeniya O Lukyanenko, Jia-Hua Qu, Miguel Calvo-Rubio Barrera, Magdalena Juhaszova, Yelena S Tarasova, Bruce Ziman, Richard Telljohann, Vikas Kumar, Mark Ranek, John Lammons, Rostislav Bychkov, Rafael de Cabo, Seungho Jun, Gizem Keceli, Ashish Gupta, Dongmei Yang, Miguel A Aon, Luigi Adamo, Christopher H Morrell, Walter Otu, Cameron Carroll, Shane Chambers, Nazareno Paolocci, Thanh Huynh, Karel Pacak, Robert Weiss, Loren Field, Steven J Sollott, Edward G Lakatta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1894a8ea0d2bfaa8df43234a7e7771be
https://doi.org/10.7554/elife.80949.sa2
https://doi.org/10.7554/elife.80949.sa2
Autor:
Kirill V. Tarasov, Khalid Chakir, Daniel R. Riordon, Alexey E. Lyashkov, Ismayil Ahmet, Maria Grazia Perino, Allwin Jennifa Silvester, Jing Zhang, Mingyi Wang, Yevgeniya O. Lukyanenko, Jia-Hua Qu, Miguel Calvo-Rubio Barrera, Magdalena Juhaszova, Yelena S Tarasova, Bruce Ziman, Richard Telljohann, Vikas Kumar, Mark Ranek, John Lammons, Rostislav Beshkov, Rafael deCabo, Seungho Jun, Gizem Keceli, Ashish Gupta, Dongmei Yang, Miguel A. Aon, Luigi Adamo, Christopher H. Morrell, Walter Otu, Cameron Carroll, Shane Chambers, Nazareno Paolocci, Thanh Huynh, Karel Pacak, Robert G Weiss, Loren Field, Steven J. Sollott, Edward G Lakatta
Adult mice with cardiac-specific overexpression of adenylyl cyclase (AC) type VIII (TGAC8) adapt to an incessantly increased cAMP-induced cardiac workload (∼30% increases in heart rate, ejection fraction and cardiac output) for up to a year without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bc7a6f588b84d86fb323e8a240cf011
https://doi.org/10.1101/2022.05.20.491883
https://doi.org/10.1101/2022.05.20.491883
Publikováno v:
SSRN Electronic Journal.