Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Richard T. Richardson"'
Autor:
Michael G. O'Rand, Richard T. Richardson, Esther E. Widgren, Erick J. R. Silva, Katherine G. Hamil
Publikováno v:
Journal of Andrology. 32:698-704
The Laboratories for Reproductive Biology at the University of North Carolina at Chapel Hill began collaboration with Human Genome Sciences (Rockville, Maryland) to sequence a human epididymal library and identify epididymal-specific genes. Among the
Publikováno v:
Biology of Reproduction. 80:279-285
Epididymal protease inhibitor (eppin [official symbol, SPINLW1]) is of interest as a male contraceptive target because of its specificity and location on the human sperm surface. We have examined the effect of anti-eppin antibodies from infertile mal
Publikováno v:
Biology of Reproduction. 77:476-484
Eppin (SPINLW1; serine peptidase inhibitor-like with Kunitz and WAP domains 1 (eppin); epididymal protease inhibitor) coats the surface of human ejaculate spermatozoa and originates from Sertoli and epididymal epithelial cells. In this study, we have
Autor:
Michael G. O'Rand, William F. Marzluff, Eric J. Wagner, Gail Grossman, Oleg M. Alekseev, Kelly D. Sullivan, Randy J. Thresher, Esther E. Widgren, Richard T. Richardson
Publikováno v:
Journal of Biological Chemistry. 281:21526-21534
A multichaperone nucleosome-remodeling complex that contains the H1 linker histone chaperone nuclear autoantigenic sperm protein (NASP) has recently been described. Linker histones (H1) are required for the proper completion of normal development, an
Publikováno v:
Gene. 371:52-58
NASP (nuclear autoantigenic sperm protein) is a histone H1 binding protein expressed in all cells undergoing division. We have previously reported the sequence for the mouse NASP gene and analyzed its proximal promoter region in silico to determine p
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 61:1-5
Nuclear autoantigenic sperm protein (NASP) is a linker histone binding protein that is cell-cycle regulated. Synchronized HeLa cells are delayed in progression through the G1/S border when transiently transfected to overexpress full-length NASP, but
Autor:
Perumal Sivashanmugam, Michael G. O'Rand, Richard T. Richardson, Zengjun Wang, Esther E. Widgren
Publikováno v:
Biology of Reproduction. 72:1064-1070
Eppin (SPINLW1; GeneID, 57119) is a single-copy gene encoding a cysteine-rich protein found only in the testis and epididymis, which contains both Kunitz-type and WAP-type four disulfide core protease inhibitor consensus sequences. This study demonst
Publikováno v:
Journal of Biological Chemistry. 280:2904-2911
NASP (nuclear autoantigenic sperm protein) is a linker histone-binding protein found in all dividing cells that is regulated by the cell cycle (Richardson, R. T., Batova, I. N., Widgren, E. E., Zheng, L. X., Whitfield, M., Marzluff, W. F., and O'Rand
Autor:
Zengjun Wang, Suresh Yenugu, Frank S. French, Susan H. Hall, Perumal Sivashanmugam, Richard T. Richardson, Michael G. O'Rand
Publikováno v:
Biology of Reproduction. 71:1484-1490
The role of epididymal sperm-binding proteins in reproductive tract immunity is now well recognized in addition to their role in sperm maturation. Spermatozoa acquire forward motility and fertilizing ability during their passage through the epididymi
Autor:
Oleg M. Alekseev, Michael G. O'Rand, Richard T. Richardson, Esther E. Widgren, David C. Bencic
Publikováno v:
Journal of Biological Chemistry. 278:8846-8852
NASP is an H1 histone-binding protein that is cell cycle-regulated and occurs in two major forms: tNASP, found in gametes, embryonic cells, and transformed cells; and sNASP, found in all rapidly dividing somatic cells (Richardson, R. T., Batova, I. N