Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Richard T. Piszczatowski"'
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::102c27e102650e4a9efbb795965b8b9c
https://doi.org/10.1016/b978-0-12-821618-7.00193-0
https://doi.org/10.1016/b978-0-12-821618-7.00193-0
Autor:
Richard T. Piszczatowski, Emily Schwenger, Sriram Sundaravel, Catarina M. Stein, Yang Liu, Pamela Stanley, Amit Verma, Deyou Zheng, Ronald D. Seidel, Steven C. Almo, Robert A. Townley, Hannes E. Bülow, Ulrich Steidl
Publikováno v:
The Journal of experimental medicine. 219(11)
Cell surfaces display a wide array of molecules that confer identity. While flow cytometry and cluster of differentiation (CD) markers have revolutionized cell characterization and purification, functionally heterogeneous cellular subtypes remain unr
Autor:
Kira Gritsman, Ulrich Steidl, Hideki Makishima, Britta Will, Richard T. Piszczatowski, Wendy M. McKimpson, Cassandra M. Hirsch, Kelly Mitchell, Christine McMahon, Boris Bartholdy, Swathi Rao Narayanagari, Richard N. Kitsis, Robert F. Stanley, Tihomira I. Todorova, Jaroslaw P. Maciejewski, Dagmar Walter
Publikováno v:
Journal of Experimental Medicine. 214:753-771
Despite the identification of several oncogenic driver mutations leading to constitutive JAK–STAT activation, the cellular and molecular biology of myeloproliferative neoplasms (MPN) remains incompletely understood. Recent discoveries have identifi
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(16)
Myelofibrosis is characterized by bone marrow fibrosis, atypical megakaryocytes, splenomegaly, constitutional symptoms, thrombotic and hemorrhagic complications, and a risk of evolution to acute leukemia. The JAK kinase inhibitor ruxolitinib provides
Publikováno v:
Cellular Signalling. 28:1604-1613
The CCN family is composed of six cysteine-rich, modular, and conserved proteins whose functions span a variety of tissues and include cell proliferation, adhesion, angiogenesis, and wound healing. Roles for the CCN proteins throughout the entire bod
Publikováno v:
Journal of Cellular Physiology. 230:2634-2639
Connective Tissue Growth Factor (CCN2/CTGF) and Nephroblastoma Overexpressed (CCN3/NOV) execute key functions within the hematopoietic compartment. Both are abundant in the bone marrow stroma, which is a niche for hematopoiesis and supports marrow fu
Publikováno v:
Biochemical and Biophysical Research Communications. 451:137-141
Recently, new tissue-specific functions for glyceraldehyde 3-phosphate dehydrogenase (GAPDH) have been discovered, aside from its archetypal function in glycolysis. This casts doubt on the legitimacy of using GAPDH as a normalization control for gene
Autor:
Robert F, Stanley, Richard T, Piszczatowski, Boris, Bartholdy, Kelly, Mitchell, Wendy M, McKimpson, Swathi, Narayanagari, Dagmar, Walter, Tihomira I, Todorova, Cassandra, Hirsch, Hideki, Makishima, Britta, Will, Christine, McMahon, Kira, Gritsman, Jaroslaw P, Maciejewski, Richard N, Kitsis, Ulrich, Steidl
Publikováno v:
The Journal of Experimental Medicine
Stanley et al. show that loss of Nol3 in mice leads to a myeloproliferative phenotype resembling primary myelofibrosis, with activation of JAK–STAT signaling and significant cellular and molecular resemblance to human disease. These findings provid
Autor:
Richard T, Piszczatowski, Brian J, Rafferty, Andre, Rozado, James V, Parziale, Nathan H, Lents
Publikováno v:
Journal of cellular physiology. 230(11)
Connective Tissue Growth Factor (CCN2/CTGF) and Nephroblastoma Overexpressed (CCN3/NOV) execute key functions within the hematopoietic compartment. Both are abundant in the bone marrow stroma, which is a niche for hematopoiesis and supports marrow fu
Publikováno v:
The FASEB Journal. 28
CCN2, also known as CTGF, the connective tissue growth factor, has recently been found to be in high abundance in platelets and released upon activation, an effect inhibited by aspirin, suggesting ...