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This chapter briefly describes some of the ethical issues involved in animal research and to summarize the current regulatory standards under which biomedical research using animals, including orthopaedic research, is conducted. The Public Health Ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e00b4778c0b50a93e451c5acc8ebead7
https://doi.org/10.1201/9780429173479-2
https://doi.org/10.1201/9780429173479-2
Autor:
K. Boschert, J. Thurmon, Richard T. Fosse, J. Stevens, M. Ganter, Ulf Sjöstrand, Tore Framstad, P. A. Flecknell
Publikováno v:
Laboratory Animals. 30:209-219
Ketamine, when used as a mono-anaesthetic, does not appear to induce surgical anaesthesia in the pig. The addition of other drugs such as opioids, benzodiazepines and α2-adrenergic agonists deepens anaesthesia and enables major surgery to be perform
Autor:
Richard T. Fosse, Steinar Hunskaar
Publikováno v:
Laboratory Animals. 27:206-221
Allergy to laboratory animals is reviewed from a management point of view. Personnel issues, medical therapy, legal aspects, animal house environments and work routines are discussed. Modern methods of medical treatment are presented but it is recomm
Autor:
Richard T. Fosse, Steinar Hunskaar
Publikováno v:
Laboratory Animals. 24:358-379
Allergy to laboratory animals (mice and rats) is reviewed. Immunological aspects, the relevant allergens, epidemiology, clinical manifestations, diagnosis and prognosis are discussed. Results presented in some studies are analysed and criticized.
Autor:
Jan Erik Nordrehaug, Richard T. Fosse, Hilda Emilia A. Andersen, Reidar J. Pettersen, Karel K.J. Kuiper
Publikováno v:
Laboratory animals. 32(3)
Post-procedure pain is a common complication in swine following survival angioplastic procedures. Ketorolac and buprenorphine have been used to control pain in these animals. Time from completion of procedure-extubation to onset of feeding was used a
Publikováno v:
Laboratory animals. 32(3)
The domestic pig is a useful model in certain areas of biomedical research. Effective use of this species is often encumbered by lack of reference values in conscious as well as anaesthetized animals. Anaesthesia itself influences physiological and b
Publikováno v:
Laboratory animals. 29(4)
When establishing a rabbit model for cardiovascular research in our laboratory we have used midazolam in combination with fentanyl/fluanisone (MFF) and nitrous oxide as anaesthesia. In this study we focused on the effect of the anaesthetic regimen on
Publikováno v:
Biochimica et biophysica acta. 1042(1)
The effects of 12- O -tetradecanoylphorbol 13-acetate (TPA) on hepatic lipids and key enzymes involved in esterification, hydrolysis and oxidation of long-chain fatty acids at increasing doses were investigated in rats. TPA administration tended to d
Publikováno v:
Laboratory animals. 20(4)
Shwartzman's reaction was elicited in four Chinchilla rabbits. Two of the animals were tranquillized with fentanyl-fluanisone (Hypnorm®: Janssen Pharmaceuticals). There was a reduced response in the tranquillized rabbits while the untranquillized an
Publikováno v:
Psychobiology. 16:307-307