Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Richard T Jaspers"'
Autor:
Zhichao Zheng, Lihong Wu, Zhicong Li, Ruoshu Tang, Hongtao Li, Yinyin Huang, Tianqi Wang, Shaofen Xu, Haoyu Cheng, Zhitong Ye, Dong Xiao, Xiaolin Lin, Gang Wu, Richard T Jaspers, Janak L Pathak
Publikováno v:
eLife, Vol 12 (2023)
MicroRNA-155 (miR155) is overexpressed in various inflammatory diseases and cancer, in which bone resorption and osteolysis are frequently observed. However, the role of miR155 on osteogenesis and bone mass phenotype is still unknown. Here, we report
Externí odkaz:
https://doaj.org/article/c9d1c01966474a4094cd8d3dd4343316
Autor:
Michèle MG Hillege, Andi Shi, Ricardo A Galli, Gang Wu, Philippe Bertolino, Willem MH Hoogaars, Richard T Jaspers
Publikováno v:
eLife, Vol 11 (2022)
In skeletal muscle, transforming growth factor-β (TGF-β) family growth factors, TGF-β1 and myostatin, are involved in atrophy and muscle wasting disorders. Simultaneous interference with their signalling pathways may improve muscle function; howev
Externí odkaz:
https://doaj.org/article/e3a9868a263f44ff871063dfe9851fd7
Autor:
Hessel Honkoop, Dennis EM de Bakker, Alla Aharonov, Fabian Kruse, Avraham Shakked, Phong D Nguyen, Cecilia de Heus, Laurence Garric, Mauro J Muraro, Adam Shoffner, Federico Tessadori, Joshua Craiger Peterson, Wendy Noort, Alberto Bertozzi, Gilbert Weidinger, George Posthuma, Dominic Grün, Willem J van der Laarse, Judith Klumperman, Richard T Jaspers, Kenneth D Poss, Alexander van Oudenaarden, Eldad Tzahor, Jeroen Bakkers
Publikováno v:
eLife, Vol 8 (2019)
While the heart regenerates poorly in mammals, efficient heart regeneration occurs in zebrafish. Studies in zebrafish have resulted in a model in which preexisting cardiomyocytes dedifferentiate and reinitiate proliferation to replace the lost myocar
Externí odkaz:
https://doaj.org/article/88c04f2d61d943049ee30a6c5dc0b5c0
Autor:
Antong Wu, Ying Zhang, Wei Cao, Xinhong Wang, Zhiqiang Song, Richard T. Jaspers, Lu Chen, Janak L. Pathak, Qingbin Zhang
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous disorder characterized by recurrent edema, facial palsies, and nerve dysfunctions often associated with the plicata tongue. Although the etiology of MRS is not well
Externí odkaz:
https://doaj.org/article/4b460219f5ac41eda351b64ba8f2f452
Autor:
Helga Haberfehlner, Richard T Jaspers, Erich Rutz, Jaap Harlaar, Johannes A van der Sluijs, Melinda M Witbreuk, Kim van Hutten, Jacqueline Romkes, Marie Freslier, Reinald Brunner, Jules G Becher, Huub Maas, Annemieke I Buizer
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192573 (2018)
To improve gait in children with spastic paresis due to cerebral palsy or hereditary spastic paresis, the semitendinosus muscle is frequently lengthened amongst other medial hamstring muscles by orthopaedic surgery. Side effects on gait due to weaken
Externí odkaz:
https://doaj.org/article/125ea5afc2044c2a9acf9bf44a3d2e30
Autor:
Helga Haberfehlner, Richard T Jaspers, Erich Rutz, Jules G Becher, Jaap Harlaar, Johannes A van der Sluijs, Melinda M Witbreuk, Jacqueline Romkes, Marie Freslier, Reinald Brunner, Huub Maas, Annemieke I Buizer
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166401 (2016)
To increase knee range of motion and improve gait in children with spastic paresis (SP), the semitendinosus muscle (ST) amongst other hamstring muscles is frequently lengthened by surgery, but with variable success. Little is known about how the pre-
Externí odkaz:
https://doaj.org/article/c6fd2879feb44d38828392fb31ed8272
Autor:
Stephan van der Zwaard, Richard T Jaspers, Ilse J Blokland, Chantal Achterberg, Jurrian M Visser, Anne R den Uil, Mathijs J Hofmijster, Koen Levels, Dionne A Noordhof, Arnold de Haan, Jos J de Koning, Willem J van der Laarse, Cornelis J de Ruiter
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162914 (2016)
BACKGROUND:Near-infrared spectroscopy (NIRS) measurements of oxygenation reflect O2 delivery and utilization in exercising muscle and may improve detection of a critical exercise threshold. PURPOSE:First, to detect an oxygenation breakpoint (Δ[O2HbM
Externí odkaz:
https://doaj.org/article/ce90e12598234c3281acdc1e04c8a982
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101038 (2014)
Cerebral palsy (CP) of the spastic type is a neurological disorder characterized by a velocity-dependent increase in tonic stretch reflexes with exaggerated tendon jerks. Secondary to the spasticity, muscle adaptation is presumed to contribute to lim
Externí odkaz:
https://doaj.org/article/9152c41249c44e8c986e6306da6050ca
Autor:
Ramaswamy Krishnan, Chan Young Park, Yu-Chun Lin, Jere Mead, Richard T Jaspers, Xavier Trepat, Guillaume Lenormand, Dhananjay Tambe, Alexander V Smolensky, Andrew H Knoll, James P Butler, Jeffrey J Fredberg
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5486 (2009)
Every adherent eukaryotic cell exerts appreciable traction forces upon its substrate. Moreover, every resident cell within the heart, great vessels, bladder, gut or lung routinely experiences large periodic stretches. As an acute response to such str
Externí odkaz:
https://doaj.org/article/23799046e6ae4143a519145515d80ed6
Autor:
Nina Jacobs, Daniek Mos, Frank W. Bloemers, Willem J. van der Laarse, Richard T. Jaspers, Stephan van der Zwaard
Publikováno v:
European Journal of Applied Physiology. Springer Verlag
Jacobs, N, Mos, D, Bloemers, F W, van der Laarse, W J, Jaspers, R T & van der Zwaard, S 2023, ' Low myoglobin concentration in skeletal muscle of elite cyclists is associated with low mRNA expression levels ', European Journal of Applied Physiology, vol. 123, no. 7, pp. 1469-1478 . https://doi.org/10.1007/s00421-023-05161-z
Jacobs, N, Mos, D, Bloemers, F W, van der Laarse, W J, Jaspers, R T & van der Zwaard, S 2023, ' Low myoglobin concentration in skeletal muscle of elite cyclists is associated with low mRNA expression levels ', European Journal of Applied Physiology, vol. 123, no. 7, pp. 1469-1478 . https://doi.org/10.1007/s00421-023-05161-z
Myoglobin is essential for oxygen transport to the muscle fibers. However, measurements of myoglobin (Mb) protein concentrations within individual human muscle fibers are scarce. Recent observations have revealed surprisingly low Mb concentrations in