Výsledky vyhledávání - "Richard T, Robertson"

Effects of concussion on the blood-brain barrier in humans and rodents

Autor: Paula Gutierrez, Ronald Sahyouni, Eric M. Gold, Richard T. Robertson, Brian J. Cummings

Publikováno v: Journal of Concussion, Vol 1 (2017)
Journal of concussion

Traumatic brain injury and the long-term consequences of repeated concussions constitute mounting concerns in the United States, with 5.3 million individuals living with a traumatic brain injury-related disability. Attempts to understand mechanisms a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871b617d565e2891832d4408231a33a8
https://pubmed.ncbi.nlm.nih.gov/30828466

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Neurotrophic factors rescue basal forebrain cholinergic neurons and improve performance on a spatial learning test

Autor: Jen Yu, Richard T. Robertson, Andalib Danandeh, Janie Baratta, Yu Shang Lee, Ching Yi Lin

Publikováno v: Lee, YS; Danandeh, A; Baratta, J; Lin, CY; Yu, J; & Robertson, RT. (2013). Neurotrophic factors rescue basal forebrain cholinergic neurons and improve performance on a spatial learning test. Experimental Neurology, 249, 178-186. doi: 10.1016/j.expneurol.2013.08.012. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/74t3r3qf

This study investigated whether animals sustaining experimental damage to the basal forebrain cholinergic system would benefit from treatment with exogenous neurotrophic factors. Specifically, we set out to determine whether neurotrophic factors woul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fd6375335f224e263e45fed94e0bcc
https://doi.org/10.1016/j.expneurol.2013.08.012

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Binding patterns of peptide-containing liposomes in liver and spleen of developing mice: comparison with heparan sulfate immunoreactivity

Autor: Monica S. Tsai, Kenneth J. Longmuir, Janie Baratta, Richard T. Robertson

Publikováno v: Journal of Drug Targeting. 19:506-515

Liposomes incorporating peptide from the Plasmodium circumsporozoite protein (CSP) accumulate rapidly and selectively in adult mouse liver.The development of the liposome-binding pattern in liver and spleen was studied in relationship to the developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dcc506e8a28668db27590cbd51919e
https://doi.org/10.3109/1061186x.2010.511227

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Amyloid-β expression in retrosplenial cortex of triple transgenic mice: relationship to cholinergic axonal afferents from medial septum

Autor: Janie Baratta, Jen Yu, Richard T. Robertson, Frank M. LaFerla

Publikováno v: Neuroscience. 164:1334-1346

Triple transgenic (3xTg-AD) mice harboring the presenilin 1, amyloid precursor protein, and tau transgenes (Oddo et al., 2003b) display prominent levels of amyloid-beta (Abeta) immunoreactivity in forebrain regions. The Abeta immunoreactivity is firs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924eb2d5bb9b9f2c9d2c4529755f92ab
https://doi.org/10.1016/j.neuroscience.2009.09.024

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Liposomal delivery of doxorubicin to hepatocytes in vivo by targeting heparan sulfate

Autor: Kenneth J. Longmuir, Sherry M. Haynes, Richard T. Robertson, Natasha Kasabwalla, Janie Baratta

Publikováno v: International Journal of Pharmaceutics. 382:222-233

Previous work demonstrated that liposomes, containing an amino acid sequence that binds to hepatic heparan sulfate glycosaminoglycan, show effective targeting to liver hepatocytes. These liposomes were tested to determine whether they can deliver dox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e360f535800b1de4e075f2d4b65af3
https://doi.org/10.1016/j.ijpharm.2009.07.030

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Liposomal Polyethyleneglycol and Polyethyleneglycol-Peptide Combinations for Active Targeting to LiverIn Vivo

Autor: Kenneth J. Longmuir, Sherry M. Haynes, Richard T. Robertson, Alan J. Waring, Janie Baratta

Publikováno v: Drug Delivery. 15:207-217

This report describes the development and evaluation of a range of polyethyleneglycol and polyethyleneglycol-peptide liposome formulations that effectively target liver in vivo. A 19-amino-acid sequence from the N-terminal region of the circumsporozo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6b9d49c2496b3611a7e7475369babf4
https://doi.org/10.1080/10717540802006211

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Repair of spinal cord transection and its effects on muscle mass and myosin heavy chain isoform phenotype

Autor: Ching Yi Lin, Yu Shang Lee, Jen Yu, Vernon W. Lin, Richard T. Robertson, Vincent J. Caiozzo

Publikováno v: Journal of Applied Physiology. 103:1808-1814

A number of significant advances have been developed for treating spinal cord injury during the past two decades. The combination of peripheral nerve grafts and acidic fibroblast growth factor (hereafter referred to as PNG) has been shown to partiall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e5c60cd336380add2d5eeb04f8472c
https://doi.org/10.1152/japplphysiol.00588.2007

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Development, differentiation, and vascular components of subcutaneous and intrahepatic Hepa129 tumors in a mouse model of hepatocellular carcinoma

Autor: Richard T, Robertson, Paula M, Gutierrez, Janie L, Baratta, Kristoffer, Thordarson, Joshua, Braslow, Sherry M, Haynes, Kenneth J, Longmuir

Publikováno v: Histology and histopathology. 31(4)

Tumor models in mice offer opportunities for understanding tumor formation and development of therapeutic treatments for hepatocellular carcinoma. In this study, subcutaneous or intra-hepatic Hepa129 tumors were established in C3H mice. Tumor growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d9ce91cb535d4a3522db0ce258fe1e2
https://pubmed.ncbi.nlm.nih.gov/26549274

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Use of labeled tomato lectin for imaging vasculature structures

Autor: Samantha T. Levine, Janie Baratta, Paula Gutierrez, Kenneth J. Longmuir, Zhiqun Tan, Sherry M. Haynes, Richard T. Robertson

Publikováno v: Histochemistry and Cell Biology, vol 143, iss 2
Histochemistry and cell biology, vol 143, iss 2
Robertson, RT; Levine, ST; Haynes, SM; Gutierrez, P; Baratta, JL; Tan, Z; et al.(2014). Use of labeled tomato lectin for imaging vasculature structures. Histochemistry and Cell Biology. doi: 10.1007/s00418-014-1301-3. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9dd978mn
Robertson, RT; Levine, ST; Haynes, SM; Gutierrez, P; Baratta, JL; Tan, Z; et al.(2014). Use of labeled tomato lectin for imaging vasculature structures. Histochemistry and Cell Biology, 143(2), 225-234. doi: 10.1007/s00418-014-1301-3. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0kr3m8pn

© 2014, Springer-Verlag Berlin Heidelberg. Intravascular injections of fluorescent or biotinylated tomato lectin were tested to study labeling of vascular elements in laboratory mice. Injections of Lycopersicon esculentum agglutinin (tomato lectin)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a62ea140a1c3c59ff8895b98b10deb2
https://escholarship.org/uc/item/0kr3m8pn

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Patterns of afferent projections to the dentate gyrus studied in organotypic co-cultures

Autor: Amy Tran, Jen Yu, Janie Baratta, Kathleen M. Guthrie, Richard T. Robertson

Publikováno v: Developmental Brain Research. 157:162-171

Cholinergic axons originating from the septum form a characteristic layer of preterminal axons and apparent termination in the molecular layer of the hippocampal dentate gyrus. The present study explored the specificity of this characteristic axonal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fac7f2eea1d143a8cc5ba6823a9bb9
https://doi.org/10.1016/j.devbrainres.2005.04.002

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