Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Richard Surosky"'
Autor:
Yoko Marwidi, Hoang-Oanh B. Nguyen, David Santos, Tenzin Wangzor, Sumita Bhardwaj, Gabriel Ernie, Gregg Prawdzik, Garrett Lew, David Shivak, Michael Trias, Jada Padilla, Hung Tran, Kathleen Meyer, Richard Surosky, Alex Michael Ward
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101228- (2024)
Manufacturing of adeno-associated viruses (AAV) for gene and cell therapy applications has increased significantly and spurred development of improved mammalian and insect cell-based production systems. We developed a baculovirus-based insect cell pr
Externí odkaz:
https://doaj.org/article/cc8de2e15a6c4613942f48ea926bb8b5
An engineered transcription factor which activates VEGF-A enhances recovery after spinal cord injury
Autor:
Yang Liu, Sarah Figley, S. Kaye Spratt, Gary Lee, Dale Ando, Richard Surosky, Michael G. Fehlings
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 2, Pp 384-393 (2010)
Spinal cord injury (SCI) leads to local vascular disruption and progressive ischemia, which contribute to secondary degeneration. Enhancing angiogenesis through the induction of vascular endothelial growth factor (VEGF)-A expression therefore constit
Externí odkaz:
https://doaj.org/article/874e75f71bc2451b9a566baa4ae23a11
Autor:
Sarah A Figley, Yang Liu, Spyridon K Karadimas, Kajana Satkunendrarajah, Peter Fettes, S Kaye Spratt, Gary Lee, Dale Ando, Richard Surosky, Martin Giedlin, Michael G Fehlings
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96137 (2014)
Following spinal cord injury (SCI) there are drastic changes that occur in the spinal microvasculature, including ischemia, hemorrhage, endothelial cell death and blood-spinal cord barrier disruption. Vascular endothelial growth factor-A (VEGF-A) is
Externí odkaz:
https://doaj.org/article/324faa1c054a4a2b9902448c459c4e79
Autor:
Bryan, Zeitler, Steven, Froelich, Kimberly, Marlen, David A, Shivak, Qi, Yu, Davis, Li, Jocelynn R, Pearl, Jeffrey C, Miller, Lei, Zhang, David E, Paschon, Sarah J, Hinkley, Irina, Ankoudinova, Stephen, Lam, Dmitry, Guschin, Lexi, Kopan, Jennifer M, Cherone, Hoang-Oanh B, Nguyen, Guijuan, Qiao, Yasaman, Ataei, Matthew C, Mendel, Rainier, Amora, Richard, Surosky, Josee, Laganiere, B Joseph, Vu, Anand, Narayanan, Yalda, Sedaghat, Karsten, Tillack, Christina, Thiede, Annette, Gärtner, Seung, Kwak, Jonathan, Bard, Ladislav, Mrzljak, Larry, Park, Taneli, Heikkinen, Kimmo K, Lehtimäki, Marie M, Svedberg, Jenny, Häggkvist, Lenke, Tari, Miklós, Tóth, Andrea, Varrone, Christer, Halldin, Andrea E, Kudwa, Sylvie, Ramboz, Michelle, Day, Jyothisri, Kondapalli, D James, Surmeier, Fyodor D, Urnov, Philip D, Gregory, Edward J, Rebar, Ignacio, Muñoz-Sanjuán, H Steve, Zhang
Publikováno v:
Nature medicine. 25(7)
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since normal HTT is thought to be important
Autor:
Fred S. Rosen, Richard Surosky, Tracy L. Hagemann, Hans Lehrach, Anthony P. Monaco, Sau-Ping Kwan
By using yeast artificial chromosome (YAC) clones, we have generated a physical map of the short arm of the human X chromosome at Xp11.23. The region analyzed spans the distal marker UBE1 and the ARAF1/TIMP/SYN1/PFC gene cluster and further extends p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229abb349d9951b5b8e493146575a66d
https://doi.org/10.1006/geno.1994.1255
https://doi.org/10.1006/geno.1994.1255
Publikováno v:
Genetics. 117(1)
The Suppressor-mutator (Spm) transposable element family of maize consists of the fully functional standard Spm (Spm-s) and many mutant elements. Insertion of an Spm element in or near a gene can markedly alter its expression, in some cases bringing