Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Richard Stratford"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2695-2707 (2024)
Background: The accurate computational prediction of B cell epitopes can vastly reduce the cost and time required for identifying potential epitope candidates for the design of vaccines and immunodiagnostics. However, current computational tools for
Externí odkaz:
https://doaj.org/article/2693960953f94fd18bcf44205e276a37
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background The HLA complex is the most polymorphic region of the human genome, and its improved characterization can help us understand the genetics of human disease as well as the interplay between cancer and the immune system. The main fun
Externí odkaz:
https://doaj.org/article/2cd99df491b14afd83793d3d34fff35b
Autor:
Yusuke Sugita, Daisuke Muraoka, Ayako Demachi-Okamura, Hiroyasu Komuro, Katsuhiro Masago, Eiichi Sasaki, Yasunori Fukushima, Takuya Matsui, Shuichi Shinohara, Yusuke Takahashi, Reina Nishida, Chieko Takashima, Teppei Yamaguchi, Yoshitsugu Horio, Kana Hashimoto, Ichidai Tanaka, Hiroshi Hamana, Hiroyuki Kishi, Daiki Miura, Yuki Tanaka, Kousuke Onoue, Kazuhide Onoguchi, Yoshiko Yamashita, Richard Stratford, Trevor Clancy, Rui Yamaguchi, Hiroaki Kuroda, Hironori Ishibashi, Kenichi Okubo, Hirokazu Matsushita
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Isolation of tumor-specific T cells and their antigen receptors (TCRs) from malignant pleural effusions (MPE) may facilitate the development of TCR-transduced adoptive cellular immunotherapy products for advanced lung cancer patients. However, the ch
Externí odkaz:
https://doaj.org/article/bd4e64d8943a4db78763ab7d7b778ba1
Autor:
Morten Nielsen, Tine Monberg, Vibeke Sundvold, Benedetta Albieri, Dorrit Hovgaard, Michael Mørk Petersen, Anders Krarup-Hansen, Özcan Met, Ketil Camilio, Trevor Clancy, Richard Stratford, Baldur Sveinbjornsson, Øystein Rekdal, Niels Junker, Inge Marie Svane
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTLTX-315 is an oncolytic peptide that elicits both local and systemic immune responses upon intratumoral injection. In the present pilot trial, we treated patients with metastatic soft tissue sarcoma with the combination of LTX-315 and adoptiv
Externí odkaz:
https://doaj.org/article/be8b6380d15946d0be5185169cae65f6
Autor:
Lorenzo Federico, Brandon Malone, Simen Tennøe, Viktoriia Chaban, Julie Røkke Osen, Murat Gainullin, Eva Smorodina, Hassen Kared, Rahmad Akbar, Victor Greiff, Richard Stratford, Trevor Clancy, Ludvig Andre Munthe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/71696a78c10c4e30a836d19c193d086e
Autor:
Murat Gainullin, Lorenzo Federico, Julie Røkke Osen, Viktoriia Chaban, Hassen Kared, Amin Alirezaylavasani, Fridtjof Lund-Johansen, Gull Wildendahl, Jon-Aksel Jacobsen, Hina Sarwar Anjum, Richard Stratford, Simen Tennøe, Brandon Malone, Trevor Clancy, John T. Vaage, Kathleen Henriksen, Linda Wüsthoff, Ludvig A. Munthe
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
People who use drugs (PWUD) are at a high risk of contracting and developing severe coronavirus disease 2019 (COVID-19) and other infectious diseases due to their lifestyle, comorbidities, and the detrimental effects of opioids on cellular immunity.
Externí odkaz:
https://doaj.org/article/c20fe6e863f8400ab809e52ef269899f
Autor:
Lorenzo Federico, Brandon Malone, Simen Tennøe, Viktoriia Chaban, Julie Røkke Osen, Murat Gainullin, Eva Smorodina, Hassen Kared, Rahmad Akbar, Victor Greiff, Richard Stratford, Trevor Clancy, Ludvig Andre Munthe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
During the COVID-19 pandemic we utilized an AI-driven T cell epitope prediction tool, the NEC Immune Profiler (NIP) to scrutinize and predict regions of T cell immunogenicity (hotspots) from the entire SARS-CoV-2 viral proteome. These immunogenic reg
Externí odkaz:
https://doaj.org/article/196a2fd0f4914004b3f5f63d54028800
Autor:
Irantzu Anzar, Brandon Malone, Pubudu Samarakoon, Ioannis Vardaxis, Boris Simovski, Hugues Fontenelle, Leonardo A. Meza-Zepeda, Richard Stratford, Emily Z. Keung, Melissa Burgess, Hussein A. Tawbi, Ola Myklebost, Trevor Clancy
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSarcomas are comprised of diverse bone and connective tissue tumors with few effective therapeutic options for locally advanced unresectable and/or metastatic disease. Recent advances in immunotherapy, in particular immune checkpoint inhi
Externí odkaz:
https://doaj.org/article/53e7fb56ac8c4288a24bd58dd3d4124a
Autor:
Hiroyuki Kishi, Hirokazu Matsushita, Hiroshi Hamana, Yuki Tanaka, Yusuke Takahashi, Rui Yamaguchi, Hisashi Iwata, Fumiaki Watanabe, Trevor Clancy, Daisuke Muraoka, Shuichi Shinohara, Hiroyasu Komuro, Takuya Matsui, Yusuke Sugita, Ayako Demachi-Okamura, Katsuhiro Masago, Reina Nishida, Yoshiki Shigematsu, Katsutoshi Adachi, Hiroaki Kuroda, Yasunori Fukushima, Chieko Takashima, Takashi Ohki, Takashi Fukuyama, Daiki Miura, Kousuke Onoue, Kazuhide Onoguchi, Yoshiko Yamashita, Richard Stratford, Kiyoshi Doi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Background CD8+tumor infiltrating lymphocytes (TILs) are often observed in non-small cell lung cancers (NSCLC). However, the characteristics of CD8+ TILs, especially T-cell populations specific for tumor antigens, remain poorly understood.Methods Hig
Externí odkaz:
https://doaj.org/article/aa0364e659cf47c3b066373e07d1c880
Autor:
Lorenzo Federico, Tor Henrik Anderson Tvedt, Murat Gainullin, Julie Røkke Osen, Viktoriia Chaban, Katrine Persgård Lund, Lisa Tietze, Trung The Tran, Fridtjof Lund-Johansen, Hassen Kared, Andreas Lind, John Torgils Vaage, Richard Stratford, Simen Tennøe, Brandon Malone, Trevor Clancy, Anders Eivind Leren Myhre, Tobias Gedde-Dahl, Ludvig André Munthe
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Poor overall survival of hematopoietic stem cell transplantation (HSCT) recipients who developed COVID-19 underlies the importance of SARS-CoV-2 vaccination. Previous studies of vaccine efficacy have reported weak humoral responses but conflicting re
Externí odkaz:
https://doaj.org/article/12d1aa38907c4c938042e4acb5e9bb70