Immediate-release/extended-release amantadine (OS320) to treat Parkinson's disease with levodopa-induced dyskinesia: Analysis of the randomized, controlled ALLAY-LID studies

Autor: Olivier Rascol, Lars Tönges, Tina deVries, Mark Jaros, Adrian Quartel, David Jacobs, Jean-Philippe Azulay, Ernest Balaguer, Perminder Bhatia, Ivan Bodis-Wollner, Paul Brownstone, Nicolas Boulloche, Gerald J. Calegan, Giovanni Castelnovo, Kelvin L. Chou, Jean-Christophe Corvol, Fabio Danisi, Luc Defebvre, Lydia Vela Desojo, Franck Durif, Reinhard Ehret, Bradley K. Evans, Concetta Forchetti, Joseph H. Friedman, Wolfgang Fogel, Matilde Calopa Garniga, Ramon A. Gil, Paul L. Ginsberg, Mark R. Glasberg, Alida Griffith, Jeffrey W. Groves, Mark Gudesblatt, Neal Hermanowicz, Maria A. Herrera, Jean-Luc Houeto, Robert M. Hutchman, Stuart H. Isaacson, Singar Jagadeesan, Mandar Jog, Andrew Keegan, Fabian Klostermann, Pierre Krystkowiak, Jaime Kulisevsky Bojarsky, Rajeev Kumar, Dennis Lacey, Bruce Lasker, John LaVaccare, Michelle M. Lavallee, Maria Rosario Luquin Piudo, Andreas Mahler, Maria José Martí Domenech, Juan Carlos Martinez Castrillo, Laszlo J. Mate, Tilak Mendis, Leonard Verhagen Metman, Siegfried Martin Muhlack, Thomas Müller, Ariane Park, James Patton, Elizabeth Peckham, Francisco Grandas Pérez, Marcie Rabin, Gerd Reifschneider, Philippe Remy, Pablo Mir Rivera, Johannes Schwarz, Isabelle Roullet-Solignac, Gabriel Salazar, Stephen M. Sergay, Scott Sherman, Richard Shubin, Lorraine Spikol, Frank Steigerwald, Daniel D. Truong, Antonio Ugarte, Francisco Vivancos Matellano, Arnold Witte, Theresa Zesiewicz, Sarah Elizabeth Zauber

Publikováno v: Parkinsonismrelated disorders. 96

Immediate-release (IR) amantadine has been used for treatment of levodopa induced dyskinesia (LID). The immediate-release/extended-release (IR/ER) amantadine formulation OS320 (OSMOLEX ER®) contains an IR outer layer and ER core for once-daily dosin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e400f18e2a2737bd0b1b24fdaa997460
https://pubmed.ncbi.nlm.nih.gov/35227940

Delayed-type hypersensitivity response in the central nervous system during JHM virus infection requires viral specificity for protection

Autor: Richard Shubin, Stephanie S. Erlich, Mark A. Sussman, Stephen A. Stohlman, Glenn K. Matsushima

Publikováno v: Journal of Neuroimmunology

The JHM strain of mouse hepatitis virus (JHMV) elicits an I-A-restricted delayed-type hypersensitivity (DTH) response mediated by a Thy-1+, Lyt-1+, and CD4+ T cell. Adoptive transfer of these polyclonal CD4+ T cells from immunized mice prevents death

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f15aebceb07bf3dbb07e22fb181dfa6c
http://europepmc.org/articles/PMC7119880

Alleviating flu-like symptoms with dose titration and analgesics in MS patients on intramuscular interferon beta-1a therapy: a pilot study

Autor: William Au, Kim Bigley, Hart Cohen, William Hornstein, Richard Shubin, David W. Brandes

Publikováno v: Current medical research and opinion. 23(7)

To determine the effectiveness of dose titration and choice of analgesic in reducing flu-like side effects of intramuscular interferon beta-1a (i.m. IFNbeta-1a).Patients were randomly assigned to receive weekly i.m. IFNbeta-1a, with or without dose t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4982849b99140dadc907ce664ab7898
https://pubmed.ncbi.nlm.nih.gov/17588298

Phenotypic expression of X-linked dystonia-parkinsonism (lubag) in two women

Autor: H. Takahashi, Kirk C. Wilhelmsen, Stanley Fahn, Barry J. Snow, Cheryl H. Waters, Carol Moskowitz, D. B. Calne, Richard Shubin, T. G. Nygaard

Publikováno v: Neurology. 43:1555-1555

Lubag (X-linked dystonia-parkinsonism) has been considered a sex-linked recessive trait and has been mapped to the pericentromeric region of the X chromosome. We studied a 54-year-old man with lubag and two of his female first cousins. Genetic typing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4853447d545d224cdcd58cfe60ff5036
https://doi.org/10.1212/wnl.43.8.1555

Monoclonal antibodies to the matrix (El) glycoprotein of mouse hepatitis virus protect mice from encephalitis

Autor: Stephen A. Stohlman, Mark A. Sussman, Richard Shubin, Nancy Casteel, John O. Fleming

Publikováno v: Virology

Monoclonal antibodies to the matrix or E1 glycoprotein of mouse hepatitis virus (MHV) were tested for their ability to protect mice from a normally lethal challenge of MHV-4. Four antibodies were tested, and two of these, J.1.3 and J.3.9, were protec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34feaec20fb15efebfd5c305fa272c5
https://doi.org/10.1016/0042-6822(89)90415-7