Zobrazeno 1 - 10
of 482
pro vyhledávání: '"Richard Salvi"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Blast wave exposure, a leading cause of hearing loss and balance dysfunction among military personnel, arises primarily from direct mechanical damage to the mechanosensory hair cells and supporting structures or indirectly through excessive
Externí odkaz:
https://doaj.org/article/f0a96ac11a5b446b9e2ad72ee9d33d32
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
PurposeSensorineural hearing loss (SNHL) is the most common form of sensory deprivation and is often unrecognized by patients, inducing not only auditory but also nonauditory symptoms. Data-driven classifier modeling with the combination of neural st
Externí odkaz:
https://doaj.org/article/6075e131749f4a1c868e2b128869a0a4
Autor:
Zhaopeng Tong, Juan Zhang, Chunhua Xing, Xiaomin Xu, Yuanqing Wu, Richard Salvi, Xindao Yin, Fei Zhao, Yu-Chen Chen, Yuexin Cai
Publikováno v:
NeuroImage, Vol 284, Iss , Pp 120475- (2023)
Age-related hearing loss (ARHL), one of the most common sensory deficits in elderly individuals, is a risk factor for dementia; however, it is unclear how ARHL affects the decline in cognitive function. To address this issue, a connectome gradient fr
Externí odkaz:
https://doaj.org/article/fb9b3c8507c545b8a27e6a847ca70bd1
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Hearing impairment is a cardinal feature of Down syndrome (DS), but its clinical manifestations have been attributed to multiple factors. Murine models could provide mechanistic insights on various causes of hearing loss in DS. To investigate mechani
Externí odkaz:
https://doaj.org/article/775fe0127b654807a470ff617fc72d58
Autor:
Senthilvelan Manohar, Guang-Di Chen, Dalian Ding, Lijie Liu, Jian Wang, Yu-Chen Chen, Lin Chen, Richard Salvi
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Noise-induced hearing loss (NIHL), caused by direct damage to the cochlea, reduces the flow of auditory information to the central nervous system, depriving higher order structures, such as the hippocampus with vital sensory information needed to car
Externí odkaz:
https://doaj.org/article/11ca1c467da340bfa8f24f88b76d5811
Autor:
Liping Lan, Yin Liu, Yuanqing Wu, Zhen-Gui Xu, Jin-Jing Xu, Jae-Jin Song, Richard Salvi, Xindao Yin, Yu-Chen Chen, Yuexin Cai
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103862- (2022)
Summary: Background: The aberrant brain network that gives rise to the phantom sound of tinnitus is believed to determine the effectiveness of tinnitus therapies involving neuromodulation with repetitive transcranial magnetic stimulation (rTMS) and s
Externí odkaz:
https://doaj.org/article/5e6f08c84dc24733a8c1c22f39fb6976
Publikováno v:
Neurobiology of Disease, Vol 161, Iss , Pp 105541- (2021)
Fragile X (FX) syndrome is one of the leading inherited causes of autism spectrum disorder (ASD). A majority of FX and ASD patients exhibit sensory hypersensitivity, including auditory hypersensitivity or hyperacusis, a condition in which everyday so
Externí odkaz:
https://doaj.org/article/5c56de3d694d4586bf36dc13c0017d0f
Autor:
Dalian Ding, Jianghui Zhang, Fang Liu, Peng Li, Weidong Qi, Yazhi Xing, Haibo Shi, Haiyan Jiang, Hong Sun, Shankai Yin, Richard Salvi
Publikováno v:
Journal of Otology, Vol 15, Iss 1, Pp 36-40 (2020)
The imbalance of reactive oxygen species and antioxidants is considered to be an important factor in the cellular injury of the inner ear. At present, great attention has been placed on oxidative stress. However, little is known about fighting oxidat
Externí odkaz:
https://doaj.org/article/20fb8dbe0abd460ab8739860160324ba
Autor:
Hyo-Jin Park, Mi-Jung Kim, Christina Rothenberger, Ashok Kumar, Edith M. Sampson, Dalian Ding, Chul Han, Karessa White, Kevin Boyd, Senthilvelan Manohar, Yong-Hwan Kim, Maria S. Ticsa, Aaron S. Gomez, Isabela Caicedo, Upal Bose, Paul J. Linser, Takuya Miyakawa, Masaru Tanokura, Thomas C. Foster, Richard Salvi, Shinichi Someya
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
A common complication of cisplatin-based chemotherapy is hearing loss. Here, Park et al. show that glutathione transferase α4 (GSTA4) contributes to reducing cisplatin toxicity in the inner ear of female mice by removing 4-hydroxynonenal (4-HNE).
Externí odkaz:
https://doaj.org/article/a4b9d8b940ff4c42bbb2c14bdd319a1a
Autor:
Dalian Ding, Haiyan Jiang, Senthilvelan Manohar, Xiaopeng Liu, Li Li, Guang-Di Chen, Richard Salvi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
2-Hyroxypropyl-beta-cyclodextrin (HPβCD) is being used to treat Niemann-Pick C1, a fatal neurodegenerative disease caused by abnormal cholesterol metabolism. HPβCD slows disease progression, but unfortunately causes severe, rapid onset hearing loss
Externí odkaz:
https://doaj.org/article/5630d4e5b7dc49d89ae5af957b8acc13