Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Richard S. Rogers"'
Autor:
Jason C. Rouse, Anders Lund, Richard S. Rogers, X. Christopher Yu, Da Ren, John F. Valliere-Douglass
Publikováno v:
Journal of Pharmaceutical Sciences. 110:619-626
In this commentary, we will provide a high-level introduction into LC-MS product characterization methodologies deployed throughout biopharmaceutical development. The ICH guidelines for early and late phase filings is broad so that it is applicable t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69843b74f1ab54d037f0d4cdb0869c75
https://doi.org/10.1016/j.xphs.2020.11.007
https://doi.org/10.1016/j.xphs.2020.11.007
Autor:
Jeffrey J. James, Alison J. Gillespie, Yuko Ogata, J. Alaina Floyd, Jeremy M. Shaver, Nancy S. Nightlinger, Richard S. Rogers, Unjy Park, Bruce A. Kerwin
Publikováno v:
Journal of Pharmaceutical Sciences
Formulation screening for biotherapeutics can cover a vast array of excipients and stress conditions. These studies consume quantities of limited material and, with higher concentrated therapeutics, more material is needed. Here, we evaluate the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a663e9c40b3c2367209d1121440b4fe8
https://doi.org/10.1016/j.xphs.2019.10.027
https://doi.org/10.1016/j.xphs.2019.10.027
Autor:
Matthew D Sekedat, David Fenyö, Richard S Rogers, Alan J Tackett, John D Aitchison, Brian T Chait
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-10 (2010)
Abstract Previous studies have led to a picture wherein the replication of DNA progresses at variable rates over different parts of the budding yeast genome. These prior experiments, focused on production of nascent DNA, have been interpreted to impl
Externí odkaz:
https://doaj.org/article/4e7f2e0b8e3a47709b20fdc51234fb1a
Publikováno v:
Development of Biopharmaceutical Drug-Device Products ISBN: 9783030314149
Multi-attribute method (MAM) is a mass spectrometry (MS)-based method that is used to directly characterize and monitor many product quality attributes and impurities on biotherapeutics. MAM utilizes high-resolution/accurate mass MS data. These data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f818da71e97be6a564daa6f2aec193
https://doi.org/10.1007/978-3-030-31415-6_9
https://doi.org/10.1007/978-3-030-31415-6_9
Autor:
Dean Pettit, Kevin J. Whaley, Jane Ennis, Michael T. Trentalange, Richard S. Rogers, Danielle Pace, Alison J. Gillespie, Brittney Livingston, Edith Nalbandian, Chris Crowell, Kelly K. Arthur, Ron Gillespie, Michael H. Pauly, Yan Brodsky, Ken Timmons, James N Thomas, Larry Zeitlin, Smidt Pauline S, Clark Rutilio H
Publikováno v:
mAbs. 8:347-357
From March 2014 through February 2015, the Ebola virus spread rapidly in West Africa, resulting in almost 30,000 infections and approximately 10,000 deaths. With no approved therapeutic options available, an experimental antibody cocktail known as ZM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a826eabda805f303ddee6591711508
https://doi.org/10.1080/19420862.2015.1127492
https://doi.org/10.1080/19420862.2015.1127492
Autor:
Christopher Yu, Douglas D. Richardson, Michael J. Abernathy, Jette Wypych, Li Zang, Richard S. Rogers, Patrick Swann, Jason C. Rouse, Justin B. Sperry, Rohini Deshpande
Publikováno v:
The AAPS Journal. 20
Today, we are experiencing unprecedented growth and innovation within the pharmaceutical industry. Established protein therapeutic modalities, such as recombinant human proteins, monoclonal antibodies (mAbs), and fusion proteins, are being used to tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8c5b043aef0e3e5ffa1e6de0d40e20
https://doi.org/10.1208/s12248-017-0168-3
https://doi.org/10.1208/s12248-017-0168-3
Publikováno v:
Molecular & Cellular Proteomics
Dengue virus is considered to be the most important mosquito-borne virus worldwide and poses formidable economic and health care burdens on many tropical and subtropical countries. Dengue infection induces drastic rearrangement of host endoplasmic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287be93883bf306a116815315fdda7fa
Autor:
Arvind P. Jamakhandi, John D. Aitchison, Ramsey A. Saleem, Richard A. Rachubinski, Richard S. Rogers, David J. Dilworth, Fred D. Mast
Publikováno v:
The Journal of biological chemistry. 291(30)
Peroxisome proliferation occurs by at least two routes, division of existing peroxisomes and de novo biogenesis from the endoplasmic reticulum (ER). The proteins and molecular mechanisms governing peroxisome emergence from the ER are poorly character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194e4ad4c6400a2b68ef799183d1062a
https://pubmed.ncbi.nlm.nih.gov/27129769
https://pubmed.ncbi.nlm.nih.gov/27129769
Autor:
Brian Raught, Tharan Srikumar, Patrick G. A. Pedrioli, Stanley M. Jeram, Richard S. Rogers, Xiang Dong Zhang, H. Anne Eisenhauer, Michael J. Matunis
Publikováno v:
PROTEOMICS. 10:254-265
Ubiquitin (Ub) and the ubiquitin-like proteins (Ubls) comprise a remarkable assortment of polypeptides that are covalently conjugated to target proteins (or other biomolecules) to modulate their intracellular localization, half-life and/or activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f26daee14085e8422bad6fc9c943e2
https://doi.org/10.1002/pmic.200900648
https://doi.org/10.1002/pmic.200900648
Autor:
Licheng Shi, Jennifer Aral, Richard S. Rogers, Violeta G. Valladares, Hongyan Li, Marie E. Wright, Kevin Salyers, Eileen Johnson, Jerry Ryan Holder, Les P. Miranda, Kenneth W. Walker, George Doellgast, Colin V. Gegg, Kenneth D. Wild, Brian D. Bennett
Publikováno v:
Journal of Medicinal Chemistry. 51:7889-7897
Calcitonin gene-related peptide (CGRP) is a 37-residue neuropeptide that can be converted to a CGRP(1) receptor antagonist by the truncation of its first seven residues. CGRP(8-37), 1, has a CGRP(1) receptor K(i) = 3.2 nM but is rapidly degraded in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6e67e4b147d3e6c1d74e860256269e
https://doi.org/10.1021/jm8009298
https://doi.org/10.1021/jm8009298