Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Richard S. Agnes"'
PDF file, 116K, A) Expression levels of the wild type EGFR determined by Western blot in A431, U87-MG, and Gli36Δ5 cell lines. Cell lysates were derived from each cell type and 50 μg of each separated using SDS-PAGE. The gels were then transferred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4250e1e74ab0ee2cfeed42a6ed61d932
https://doi.org/10.1158/1535-7163.22498437
https://doi.org/10.1158/1535-7163.22498437
PDF file, 36K, Physical properties of peptides studied in this report. RP-HPLC conditions 10-60% acetonitrile against 0.1% trifluoroacetic acid over 30 minutes through a C18 column (PROTO 300, 10 micron, 250 x 4.6 mm) where the injection peak at 3.6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65aa2d2cef92199340ebc0f0ccdf2e41
https://doi.org/10.1158/1535-7163.22498428.v1
https://doi.org/10.1158/1535-7163.22498428.v1
PDF file, 46K, Peptides were characterized and verified by MALDI mass spectrometry. Table shows the expected and observed molecular weight of the peptides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037dc0acb4cee38a1836bb3acf2f8639
https://doi.org/10.1158/1535-7163.22498431
https://doi.org/10.1158/1535-7163.22498431
Molecular Imaging of Tumors Using a Quantitative T1 Mapping Technique via Magnetic Resonance Imaging
Autor:
Kelsey Herrmann, Mette L. Johansen, Sonya E. Craig, Jason Vincent, Michael Howell, Ying Gao, Lan Lu, Bernadette Erokwu, Richard S. Agnes, Zheng-Rong Lu, Jonathan K. Pokorski, James Basilion, Vikas Gulani, Mark Griswold, Chris Flask, Susann M. Brady-Kalnay
Publikováno v:
Diagnostics, Vol 5, Iss 3, Pp 318-332 (2015)
Magnetic resonance imaging (MRI) of glioblastoma multiforme (GBM) with molecular imaging agents would allow for the specific localization of brain tumors. Prior studies using T1-weighted MR imaging demonstrated that the SBK2-Tris-(Gd-DOTA)3 molecular
Externí odkaz:
https://doaj.org/article/4813a448bbc84f3db7529e66fc43a74c
Molecular Imaging of Tumors Using a Quantitative T1 Mapping Technique via Magnetic Resonance Imaging
Autor:
Vikas Gulani, Zheng-Rong Lu, Richard S. Agnes, Christopher A Flask, Susann M. Brady-Kalnay, Sonya E.L. Craig, Ying Gao, Kelsey A. Herrmann, Mette L. Johansen, Michael Howell, Bernadette O. Erokwu, James P. Basilion, Jonathan K. Pokorski, Jason Vincent, Lan Lu, Mark A. Griswold
Publikováno v:
Diagnostics
Volume 5
Issue 3
Pages 318-332
Diagnostics, Vol 5, Iss 3, Pp 318-332 (2015)
Volume 5
Issue 3
Pages 318-332
Diagnostics, Vol 5, Iss 3, Pp 318-332 (2015)
Magnetic resonance imaging (MRI) of glioblastoma multiforme (GBM) with molecular imaging agents would allow for the specific localization of brain tumors. Prior studies using T 1-weighted MR imaging demonstrated that the SBK2-Tris-(Gd-DOTA)3 molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b253154198156788a7d54b7657e67132
http://europepmc.org/articles/PMC4589153
http://europepmc.org/articles/PMC4589153
Publikováno v:
Molecular Cancer Therapeutics. 11:2202-2211
We have developed a near-infrared (NIR) probe that targets cells overexpressing the EGF receptor (EGFR) for imaging glioblastoma brain tumors in live subjects. A peptide specific for the EGFR was modified with various lengths of monodiscrete polyethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7347351c50cfeca2a195e364dab1fd23
https://doi.org/10.1158/1535-7163.mct-12-0211
https://doi.org/10.1158/1535-7163.mct-12-0211
Autor:
Frank Porreca, Richard S. Agnes, Dave S. Herman, Tally M. Largent-Milnes, Isuru R. Kumarasinghe, Todd W. Vanderah, Yeon Sun Lee, Katherine E. Hanlon, Josephine Lai, Sho W. Ma, Michael H. Ossipov, Victor J. Hruby, Wenhong Guo
Publikováno v:
Brain Research. 1395:1-11
The conventional design of high affinity drugs targeted to a single molecule has not resulted in clinically useful therapies for pain relief. Recent reviews have suggested that newly designed analgesic drugs should incorporate multiple targets. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a387a6d1ba0ca13ead0c9f8a37dd990
https://doi.org/10.1016/j.brainres.2011.04.024
https://doi.org/10.1016/j.brainres.2011.04.024
Publikováno v:
Organic Letters. 9:2249-2252
The activity of light-activatable ("caged") compounds can be temporally and spatially controlled, thereby providing a means to interrogate intracellular biochemical pathways as a function of time and space. Nearly all caged peptides contain photoclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e783e4d9e045c361c45c2d0d7254a6
https://doi.org/10.1021/ol070238t
https://doi.org/10.1021/ol070238t
Autor:
Peg Davis, Josephine Lai, Richard S. Agnes, Yeon Sun Lee, Victor J. Hruby, Sharif Moye, Shou Wu Ma, Ruben Vardanyan, Frank Porreca, Joel Nyberg
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:2161-2165
New 4-anilidopiperidine analogues in which the phenethyl group of fentanyl was replaced by several aromatic ring-contained amino acids (or acids) were synthesized to study the biological effect of the substituents on mu and delta opioid receptor inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12edf0ec7e5e8964154f9e69575dd8d9
https://doi.org/10.1016/j.bmcl.2007.01.114
https://doi.org/10.1016/j.bmcl.2007.01.114