Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Richard S, Kaplan"'
Autor:
Liz Morrell, Joshua Hordern, Louise Brown, Matthew R. Sydes, Claire L. Amos, Richard S. Kaplan, Mahesh K. B. Parmar, Timothy S. Maughan
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Trials have become bigger and more complicated due to the complexity introduced by biomarker stratification, and the advent of multi-arm multi-stage trials, and umbrella and basket platform designs. The trials unit at University C
Externí odkaz:
https://doaj.org/article/70d633848f154ef581269da3c4f91311
Autor:
Francesca Schiavone, Riya Bathia, Krishna Letchemanan, Lindsey Masters, Claire Amos, Anna Bara, Louise Brown, Clare Gilson, Cheryl Pugh, Nafisah Atako, Fleur Hudson, Mahesh Parmar, Ruth Langley, Richard S. Kaplan, Chris Parker, Gert Attard, Noel W. Clarke, Silke Gillessen, Nicholas D. James, Tim Maughan, Matthew R. Sydes, On behalf of past and present members of the STAMPEDE and FOCUS4 Trial Management Group
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background There are limited research and literature on the trial management challenges encountered in running adaptive platform trials. This trial design allows both (1) the seamless addition of new research comparisons when compelling clin
Externí odkaz:
https://doaj.org/article/6e07272452b74f78bf38922ab9f8d1a4
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
Supplementary Results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9837817e7906381d03da436c4c0aba83
https://doi.org/10.1158/1078-0432.22479923
https://doi.org/10.1158/1078-0432.22479923
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
Figures S1-S9, Tables S1, S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496cf180498237ddd1cd669c0717922a
https://doi.org/10.1158/1078-0432.22479920
https://doi.org/10.1158/1078-0432.22479920
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
Purpose:The DNA damage immune response (DDIR) assay was developed in breast cancer based on biology associated with deficiencies in homologous recombination and Fanconi anemia pathways. A positive DDIR call identifies patients likely to respond to pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b0d147fbbb30b1796bb72b6461704c
https://doi.org/10.1158/1078-0432.c.6530324.v1
https://doi.org/10.1158/1078-0432.c.6530324.v1
Autor:
Philip D. Dunne, Louise C. Brown, Timothy S. Maughan, Mark Lawler, Daniel B. Longley, Richard S. Kaplan, Letitia Campo, Viktor H. Koelzer, Ian Tomlinson, Patrick G. Johnston, Richard D. Kennedy, Manuel Salto-Tellez, Nicholas P. West, Philip Quirke, Dion G. Morton, Matthew T. Seymour, Ultan McDermott, Stephanie G. Craig, Matthew P. Humphries, Raheleh Amirkhah, Aikaterina Chatzipli, Gemma E. Logan, Steven M. Walker, Michael Youdell, Susan D. Richman, Keara L. Redmond, Sylvana Hassanieh, Andrew Blake, Enric Domingo, David J. Fisher, Sudhir B. Malla
supplementary methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3561136117c96a00b0726edbd0837c50
https://doi.org/10.1158/1078-0432.22479926.v1
https://doi.org/10.1158/1078-0432.22479926.v1
Autor:
Vasilis, Stavrinides, Joseph M, Norris, Solon, Karapanagiotis, Francesco, Giganti, Alistair, Grey, Nick, Trahearn, Alex, Freeman, Aiman, Haider, Lina María, Carmona Echeverría, Simon R J, Bott, Louise C, Brown, Nicholas, Burns-Cox, Timothy J, Dudderidge, Ahmed, El-Shater Bosaily, Maneesh, Ghei, Alastair, Henderson, Richard G, Hindley, Richard S, Kaplan, Robert, Oldroyd, Chris, Parker, Raj, Persad, Derek J, Rosario, Iqbal S, Shergill, Mathias, Winkler, Alex, Kirkham, Shonit, Punwani, Hayley C, Whitaker, Hashim U, Ahmed, Mark, Emberton
Publikováno v:
Radiology.
Background The effects of regional histopathologic changes on prostate MRI scans have not been accurately quantified in men with an elevated prostate-specific antigen (PSA) level and no previous biopsy. Purpose To assess how Gleason grade, maximum ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad338ab2d4a68592b138a54d788a496
https://pubmed.ncbi.nlm.nih.gov/36511810
https://pubmed.ncbi.nlm.nih.gov/36511810
Autor:
Louise Clare Brown, Hashim U Ahmed, Rita Faria, Ahmed El-Shater Bosaily, Rhian Gabe, Richard S Kaplan, Mahesh Parmar, Yolanda Collaco-Moraes, Katie Ward, Richard Graham Hindley, Alex Freeman, Alexander Kirkham, Robert Oldroyd, Chris Parker, Simon Bott, Nick Burns-Cox, Tim Dudderidge, Maneesh Ghei, Alastair Henderson, Rajendra Persad, Derek J Rosario, Iqbal Shergill, Mathias Winkler, Marta Soares, Eldon Spackman, Mark Sculpher, Mark Emberton
Publikováno v:
Health Technology Assessment, Vol 22, Iss 39 (2018)
Background: Men with suspected prostate cancer usually undergo transrectal ultrasound (TRUS)-guided prostate biopsy. TRUS-guided biopsy can cause side effects and has relatively poor diagnostic accuracy. Multiparametric magnetic resonance imaging (mp
Externí odkaz:
https://doaj.org/article/103fa08d2093410aa8ca49bea372765f
Autor:
Johnathan K, Joffe, Fay H, Cafferty, Laura, Murphy, Gordon J S, Rustin, Syed A, Sohaib, Rhian, Gabe, Sally P, Stenning, Elizabeth, James, Dipa, Noor, Simona, Wade, Francesca, Schiavone, Sarah, Swift, Elaine, Dunwoodie, Marcia, Hall, Anand, Sharma, Jeremy, Braybrooke, Jonathan, Shamash, John, Logue, Henry H, Taylor, Ivo, Hennig, Jeff, White, Sarah, Rudman, Jane, Worlding, David, Bloomfield, Guy, Faust, Hilary, Glen, Rachel, Jones, Michael, Seckl, Graham, MacDonald, Thiagarajan, Sreenivasan, Satish, Kumar, Andrew, Protheroe, Ramachandran, Venkitaraman, Danish, Mazhar, Victoria, Coyle, Martin, Highley, Tom, Geldart, Robert, Laing, Richard S, Kaplan, Robert A, Huddart
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(22)
PURPOSE Survival in stage I seminoma is almost 100%. Computed tomography (CT) surveillance is an international standard of care, avoiding adjuvant therapy. In this young population, minimizing irradiation is vital. The Trial of Imaging and Surveillan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32509283fdd8f055e025757fc245aebc
https://pubmed.ncbi.nlm.nih.gov/35298280
https://pubmed.ncbi.nlm.nih.gov/35298280
Autor:
Dacheng Huo, Robert A Huddart, Fay Helen Cafferty, Laura Murphy, Gordon J. S. Rustin, Syed A Sohaib, Francesca Schiavone, Richard S. Kaplan, Johnathan K Joffe, Mark Sculpher, Saramago Pedro
Publikováno v:
Journal of Clinical Oncology. 41:408-408
408 Background: Risk of radiation exposure from standard computed tomography (CT) surveillance is a major concern in the management of stage I seminoma testis patients. The TRISST randomized trial (NCT00589537) demonstrated that effective monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e42f94208583bc53c3f844ecada33ca5
https://doi.org/10.1200/jco.2023.41.6_suppl.408
https://doi.org/10.1200/jco.2023.41.6_suppl.408