Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Richard Roy"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 4, p e1010716 (2023)
During periods of energetic stress, Caenorhabditis elegans can execute a developmentally quiescent stage called "dauer", during which all germline stem cells undergo a G2 cell cycle arrest. In animals that lack AMP-activated protein kinase (AMPK) sig
Externí odkaz:
https://doaj.org/article/c4d64d05799b4316ae1b85a44e598bec
Autor:
Ken Cooper, Stephen Durden, Richard Roy, Jose Siles, Raquel Rodriguez Monje, Robert Dengler, Luis Millan, Robert Beauchamp
Publikováno v:
IEEE Journal of Microwaves, Vol 1, Iss 2, Pp 586-592 (2021)
A method for improving the dynamic range of frequency-modulated continuous-wave (FMCW) radar systems is presented. Bright echo signals detected with FMCW radars can carry strong phase noise sidelobes, especially for radars at W-band and higher freque
Externí odkaz:
https://doaj.org/article/db362880d1f3482889e40f4be296d5ed
Autor:
Sebastian Schmeisser, Shaolin Li, Bertrand Bouchard, Matthieu Ruiz, Christine Des Rosiers, Richard Roy
Publikováno v:
Cell Reports, Vol 29, Iss 13, Pp 4540-4552.e8 (2019)
Summary: A growing body of evidence suggests that changes in fat metabolism may have a significant effect on lifespan. Accumulation of lipid deposits in non-adipose tissue appears to be critical for age-related pathologies and may also contribute to
Externí odkaz:
https://doaj.org/article/e23132b8dd5743e3aa9fa2fd2d50dde1
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-19 (2018)
Abstract Background Caenorhabditis elegans can endure long periods of environmental stress by altering their development to execute a quiescent state called “dauer”. Previous work has implicated LKB1 - the causative gene in the autosomal dominant
Externí odkaz:
https://doaj.org/article/387d7bda3b7d49f68c4c0c127466fa49
Autor:
Pratik Kadekar, Richard Roy
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000309 (2019)
During suboptimal growth conditions, Caenorhabditis elegans larvae undergo a global developmental arrest called "dauer." During this stage, the germline stem cells (GSCs) become quiescent in an AMP-activated Protein Kinase (AMPK)-dependent manner, an
Externí odkaz:
https://doaj.org/article/6248481ce28143edb60ef01577dbc1a0
Autor:
Christopher Wong, Richard Roy
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2238 (2020)
Caenorhabditis elegans larvae can undergo developmental arrest upon entry into the dauer stage in response to suboptimal growth conditions. Dauer larvae can exit this stage in replete conditions with no reproductive consequence. During this diapause
Externí odkaz:
https://doaj.org/article/99cf5c7885914c3c9d33bda6eca21da0
Autor:
Meng Xie, Richard Roy
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006524 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1005284.].
Externí odkaz:
https://doaj.org/article/d51cd0442e334f739ec57b06086ee040
Autor:
Moloud Ahmadi, Richard Roy
Publikováno v:
eLife, Vol 5 (2016)
The stress associated with starvation is accompanied by compensatory behaviours that enhance foraging efficiency and increase the probability of encountering food. However, the molecular details of how hunger triggers changes in the activity of neura
Externí odkaz:
https://doaj.org/article/85434c86cf1a4b66ad0e812914332ca1
Autor:
Paul Boothe, Richard Roy
Publikováno v:
International Productivity Monitor, Iss 16, Pp 3-13 (2008)
Business sector productivity growth is central to Canadians' future prosperity. This article reviews the performance of the Canadian business sector in improving labour and multifactor productivity and examines possible factors underlying recent deve
Externí odkaz:
https://doaj.org/article/74c3dc25f9524d28b5e0d20e09845d01
Autor:
Meng Xie, Richard Roy
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005284 (2015)
AMP-activated kinase (AMPK) is a key regulator of many cellular mechanisms required for adjustment to various stresses induced by the changing environment. In C. elegans dauer larvae AMPK-null mutants expire prematurely due to hyperactive Adipose Tri
Externí odkaz:
https://doaj.org/article/a640d968c2e94c23a14b4bcaba34cc5a