Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Richard R. Stotts"'
Autor:
J. Richard Smith, Nancy A. Niemuth, Richard R. Stotts, Stephen J. Janny, John S. Graham, Shawn M. Shumaker, Frances M. Reid, F. Steven Tucker
Publikováno v:
Journal of Applied Toxicology. 20:S161-S172
Sulfur mustard (bis(2-chloroethyl)sulfide, HD) is a well-known blistering chemical warfare agent. We have developed a cutaneous full-thickness HD burn model in weanling pigs for efficacy testing of candidate treatment regimens. This report addresses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f5292d5c5a0c6df3ec00696681bace5
https://doi.org/10.1002/1099-1263(200012)20:1+<::aid-jat681>3.0.co
https://doi.org/10.1002/1099-1263(200012)20:1+<::aid-jat681>3.0.co
Publikováno v:
Journal of Applied Toxicology. 16:381-384
Phosgene, a highly reactive former warfare gas, is a deep lung irritant which produces adult respiratory distress syndrome (ARDS)-like symptoms following inhalation. Death caused by phosgene involves a latent, 6-24-h, fulminating non-cardiogenic pulm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da893d8767d1c82401304625d32c185a
https://doi.org/10.1002/(sici)1099-1263(199609)16:5<381::aid-jat355>3.0.co
https://doi.org/10.1002/(sici)1099-1263(199609)16:5<381::aid-jat355>3.0.co
Autor:
Richard R. Stotts, Felix Feliciano, Susan R. Millette, Carmen M. Arroyo, Jill R. Keeler, Dana L. Kolb
Publikováno v:
Journal of Biochemical Toxicology. 8:107-110
The reaction of phosgene with ni-trone spin traps was investigated using electron paramagnetic resonance (EPR)/spin trapping techniques. Evidence for the intermediacy of a carba-moyl monochloride intermediate was obtained. Isotopic substitution of 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcd71a7bb285db819f399ae9e963431b
https://doi.org/10.1002/jbt.2570080208
https://doi.org/10.1002/jbt.2570080208
Autor:
Kenneth L. Rinehart, Andrew M. Dahlem, Ryuichi Sakai, William R. Evans, Val R. Beasley, Richard R. Stotts, Wayne W. Carmichael, Michio Namikoshi
Publikováno v:
The Journal of Organic Chemistry. 57:866-872
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2823139059a71f117504d131f7cf9eb
https://doi.org/10.1021/jo00029a016
https://doi.org/10.1021/jo00029a016
Autor:
Richard R. Stotts, Alfred M. Sciuto
Publikováno v:
Experimental lung research. 24(3)
Acetylenic acids such as 5,8,11,14-eicosatetraynoic acid (ETYA), have been shown to be effective in preventing pulmonary edema formation (PEF). In phosgene-exposed guinea pigs, we examined the effects of ETYA on PEF, measured as real time lung weight
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0e7e7e273ab463fcf9a96af3f0bbcf
https://pubmed.ncbi.nlm.nih.gov/9635251
https://pubmed.ncbi.nlm.nih.gov/9635251
Autor:
A. Robert Twardock, Val R. Beasley, Richard R. Stotts, Kenneth L. Rinehart, Wanda M. Haschek, Byoung Wook Choi
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 35(6)
The distribution of tritiated dihydromicrocystin [3H]2H-MCLR was studied in anesthetized specific-pathogen-free pigs. Two doses were administered i.m. and one dose was given via an isolated ileal loop. At 4 hr after i.v. administration of the toxin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b252cafead16de648ba268239d94b8
https://pubmed.ncbi.nlm.nih.gov/9241787
https://pubmed.ncbi.nlm.nih.gov/9241787
Autor:
Richard R. Stotts, Twardock Ar, Gary D. Koritz, Hollis Wb, Val R. Beasley, Manuel Rk, Wanda M. Haschek
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 35(3)
The toxicokinetics of tritiated dihydromicrocystin-LR ([3H]2H-MCLR) were studied in anesthetized, specific-pathogen-free pigs. Pigs were dosed with radiolabeled plus non-labeled 2H-MCLR at 25 or 75 micrograms/kg i.v., or via an isolated ileal loop at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df25de47dce0490eb6638039a9449453
https://pubmed.ncbi.nlm.nih.gov/9080600
https://pubmed.ncbi.nlm.nih.gov/9080600
Publikováno v:
Biochemical and biophysical research communications. 226(3)
Mice, rats and guinea pigs were exposed to phosgene (COCl2), a highly irritating and oxidizing gas. Animals were exposed to 87 mg/m3 phosgene for 20 min in a whole-body exposure chamber. Within 55-65 minutes after the start of exposure, plasma was sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eefb7c9b88bb350c26c5f75f8be622f
https://pubmed.ncbi.nlm.nih.gov/8831709
https://pubmed.ncbi.nlm.nih.gov/8831709
Autor:
Andrew M. Dahlem, Wanda M. Haschek, Wayne W. Carmichael, Kenneth L. Rinehart, Val R. Beasley, Richard R. Stotts, Michio Namikoshi
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 31(6)
A cyanobacterial (blue-green algal) bloom containing Microcystis aeruginosa (dominant), M. viridis, and M. wesenbergii, was collected from Homer Lake (Illinois, U.S.A.) in the summer of 1988 and microcystins were isolated. One microcystin of substant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fe84dbf795c1bfc8f4a01229268cda
https://pubmed.ncbi.nlm.nih.gov/8342176
https://pubmed.ncbi.nlm.nih.gov/8342176