Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Richard R. Blough"'
Publikováno v:
American Journal of Clinical Oncology: Cancer Clinical Trials. 23:379-383
Menogaril is a semisynthetic anthracycline with relative lack of cardiotoxicity. Ten patients with multiple myeloma (MM), seven patients with chronic lymphocytic leukemia (CLL), and one patient with diffuse well-differentiated lymphocytic lymphoma (D
Autor:
Michael Russell Mullane, Everett E. Vokes, Merrill S. Kies, Al B. Benson, Fred Rosen, James L. Wade, Thomas E. Lad, Suzanne French, Lary J. Kilton, Richard R. Blough
Publikováno v:
Investigational New Drugs. 13:249-252
Amonafide (nafidimide), a synthetic organic compound with an inhibitory effect on cellular replication, was used in a phase II study conducted by the Illinois Cancer Center in order to assess its efficacy and toxicity in advanced or recurrent squamou
Autor:
James L. Wade, Al B. Benson, Anne Bauman, Richard R. Blough, Richard L. Schilsky, Michael Russell Mullane, Suzanne French, Rosemary Carroll, Lary J. Kilton
Publikováno v:
Investigational New Drugs. 12:267-270
Twelve patients with recurrent, metastatic, or inoperable gastric adenocarcinoma were enrolled in an Illinois Cancer Center phase II trial of amonafide (nafidimide), a novel compound that acts as a DNA intercalator. Treatment consisted of a 60-minute
Autor:
Daniel H. Shevrin, Patricia A. Johnson, Timothy M. Kuzel, Nicholas J. Vogelzang, Lary J. Kilton, James M. Kozlowski, Richard R. Blough, Martin S. Tallman, Al B. Benson, E. L. Braud
Publikováno v:
Cancer. 72:1965-1968
Background 5-Fluorouracil (5-FU) has been previously associated with therapeutic benefit in hormone refractory prostate cancer. However, no previous study has administered 5-FU as a prolonged continuous infusion, which may be the optimal schedule for
Autor:
Al B. Benson, Charles L. Shapiro, Linda Weidner, Patricia A. Johnson, Richard R. Blough, Suzanne French, Alice Greenberg, Lary J. Kilton
Publikováno v:
Investigational New Drugs. 10:201-204
We have conducted a phase II trial of fludarabine phosphate for advanced measurable adenocarcinoma of the pancreas. The drug was administered every 4 weeks by a daily-times-5 bolus schedule beginning at 20 mg/m2/day. No responses were observed in 20
Autor:
Miriam I. Redleaf, Richard R. Blough
Publikováno v:
The Annals of otology, rhinology, and laryngology. 105(4)
The middle cranial fossa approach to lesions of the geniculate ganglion and internal auditory canal preserves cochlear function and affords access to the lateral internal auditory canal. The labyrinthine portion of the facial nerve tends to course ne
Autor:
David L. Grinblatt, Melissa Runge-Morris, Samuel G. Taylor, Merrill S. Kies, Richard R. Blough, Arletrice Watkins
Publikováno v:
Investigational new drugs. 12(1)
The Illinois Cancer Center entered 25 patients on a phase II trial of intravenous melphalan treating patients with recurrent, metastatic or locally advanced and inoperable squamous cell carcinoma of the head and neck. All patients had bi-dimensionall
Autor:
Richard H. Knop, Kathy S. Albain, Thomas E. Lad, Suzanne French, Al B. Benson, Lary J. Kilton, Gershon Y. Locker, Janardan D. Khandekar, Richard R. Blough
Publikováno v:
Investigational new drugs. 12(4)
Thirty-three patients with advanced colorectal carcinoma were entered on a phase II trial of weekly IV aminothiadiazole (175 mg/m2 escalated to 200 mg/m2) with concomitant allopurinol and non-steroidal anti-inflammatory agents (NSAID's). Toxicity was
Autor:
Daniel H. Shevrin, Lary J. Kilton, Richard R. Blough, Al B. Benson, Michael Russell Mullane, Suzanne French, Thomas E. Lad, Ben Esparaz, James R. Egner, Richard H. Knop, Patricia A. Johnson
Publikováno v:
Investigational new drugs. 12(4)
Autor:
Julia B. Ashenhurst, Suzanne French, Lary J. Kilton, Al B. Benson, Gail Shiomoto, James L. Wade, Richard R. Blough, Richard L. Schilsky
Publikováno v:
Investigational new drugs. 12(2)
In an Illinois Cancer Center phase II trial, fludarabine phosphate was administered to a total of 14 patients (9 men, 5 women) with advanced, measurable, gastric adenocarcinoma. Fludarabine phosphate was given as a rapid intravenous (IV) bolus at a s