Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Richard R Fabsitz"'
Autor:
V. Saroja eVoruganti, Paul B Higgins, Sven OE Ebbesson, John ekennish, Harald HH Goring, Karin eHaack, Sandra eLaston, Eugene eDrigalenko, Charlotte R Wenger, William eHarris, Richard R Fabsitz, Richard B Devereux, Jean eMacCluer, Joanne eCurran, Melanie eCarless, Matthew eJohnson, Eric eMoses, John eBlangero, Jason G Umans, Barbara V Howard, Shelley eCole, Anthony Gean Comuzzie
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
The delta-5 and delta-6 desaturases (D5D and D6D), encoded by fatty acid desaturase 1 (FADS1) and 2 (FADS2) genes, respectively, are rate-limiting enzymes in the metabolism of ω-3 and ω-6 fatty acids. The objective of this study was to identify gen
Externí odkaz:
https://doaj.org/article/f6e6cfa6b11244f28605cb506dcf7f3d
Autor:
Guillaume Lettre, Cameron D Palmer, Taylor Young, Kenechi G Ejebe, Hooman Allayee, Emelia J Benjamin, Franklyn Bennett, Donald W Bowden, Aravinda Chakravarti, Al Dreisbach, Deborah N Farlow, Aaron R Folsom, Myriam Fornage, Terrence Forrester, Ervin Fox, Christopher A Haiman, Jaana Hartiala, Tamara B Harris, Stanley L Hazen, Susan R Heckbert, Brian E Henderson, Joel N Hirschhorn, Brendan J Keating, Stephen B Kritchevsky, Emma Larkin, Mingyao Li, Megan E Rudock, Colin A McKenzie, James B Meigs, Yang A Meng, Tom H Mosley, Anne B Newman, Christopher H Newton-Cheh, Dina N Paltoo, George J Papanicolaou, Nick Patterson, Wendy S Post, Bruce M Psaty, Atif N Qasim, Liming Qu, Daniel J Rader, Susan Redline, Muredach P Reilly, Alexander P Reiner, Stephen S Rich, Jerome I Rotter, Yongmei Liu, Peter Shrader, David S Siscovick, W H Wilson Tang, Herman A Taylor, Russell P Tracy, Ramachandran S Vasan, Kevin M Waters, Rainford Wilks, James G Wilson, Richard R Fabsitz, Stacey B Gabriel, Sekar Kathiresan, Eric Boerwinkle
Publikováno v:
PLoS Genetics, Vol 7, Iss 2, p e1001300 (2011)
Coronary heart disease (CHD) is the leading cause of mortality in African Americans. To identify common genetic polymorphisms associated with CHD and its risk factors (LDL- and HDL-cholesterol (LDL-C and HDL-C), hypertension, smoking, and type-2 diab
Externí odkaz:
https://doaj.org/article/d9f44e2061144ffba888d0850b646b15
Autor:
Brendan J Keating, Sam Tischfield, Sarah S Murray, Tushar Bhangale, Thomas S Price, Joseph T Glessner, Luana Galver, Jeffrey C Barrett, Struan F A Grant, Deborah N Farlow, Hareesh R Chandrupatla, Mark Hansen, Saad Ajmal, George J Papanicolaou, Yiran Guo, Mingyao Li, Stephanie Derohannessian, Paul I W de Bakker, Swneke D Bailey, Alexandre Montpetit, Andrew C Edmondson, Kent Taylor, Xiaowu Gai, Susanna S Wang, Myriam Fornage, Tamim Shaikh, Leif Groop, Michael Boehnke, Alistair S Hall, Andrew T Hattersley, Edward Frackelton, Nick Patterson, Charleston W K Chiang, Cecelia E Kim, Richard R Fabsitz, Willem Ouwehand, Alkes L Price, Patricia Munroe, Mark Caulfield, Thomas Drake, Eric Boerwinkle, David Reich, A Stephen Whitehead, Thomas P Cappola, Nilesh J Samani, A Jake Lusis, Eric Schadt, James G Wilson, Wolfgang Koenig, Mark I McCarthy, Sekar Kathiresan, Stacey B Gabriel, Hakon Hakonarson, Sonia S Anand, Muredach Reilly, James C Engert, Deborah A Nickerson, Daniel J Rader, Joel N Hirschhorn, Garret A Fitzgerald
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3583 (2008)
A wealth of genetic associations for cardiovascular and metabolic phenotypes in humans has been accumulating over the last decade, in particular a large number of loci derived from recent genome wide association studies (GWAS). True complex disease-a
Externí odkaz:
https://doaj.org/article/20a3c01d6d394132abfac9f27abb03be
Autor:
Valarie Jernigan, Elisa T Lee, Jeunliang Yeh, Richard R Fabsitz, Barbara V Howard, Ying Zhang
Publikováno v:
Circulation. 147
Introduction: Previous research has shown that health care access and usage patterns among Native Americans are often difficult to measure. Hypothesis: We hypothesize that sociodemographic factors such as age, gender, education, and employment influe
Autor:
Marta Galvez-Fernandez, Kishan A Bhatt, Filippo Ravalli, Walter Goessler, Ying Zhang, Amanda M Fretts, Jason G Umans, Tiffany Sanchez, Francisco Ujueta, Gervasio A Lamas, Richard R Fabsitz, Ana Navas-Acien
Publikováno v:
Circulation. 147
Background: Cadmium is a cardiotoxic divalent metal that accumulates in the liver and kidney. It resembles the essential metal zinc, replacing it in numerous enzymes and proteins. Zinc plays a major role in insulin function. Glucose dyshomeostasis in
Autor:
Shuqian Liu, MD, Wenyu Wang, PhD, Jian Zhang, PhD, Yuna He, MS, Chonghua Yao, MD, Zhechun Zeng, MD, Jianhua Piao, Barbara V. Howard, PhD, Richard R. Fabsitz, PhD, Lyle Best, PhD, Xiaoguang Yang, MD, PhD, Elisa T. Lee, PhD
Publikováno v:
Preventing Chronic Disease, Vol 8, Iss 1 (2011)
IntroductionAs a result of rapid economic development in China, the lifestyles and dietary habits of its people have been changing, and the rates of obesity, diabetes, and other chronic conditions have increased substantially. We report the prevalenc
Externí odkaz:
https://doaj.org/article/18d9a064a5f5491894ca918770c5f4a3
Autor:
Walter Goessler, Maria Tellez-Plaza, Jonathan D. Newman, Ana Navas-Acien, Eliseo Guallar, Barbara V. Howard, Kevin A. Francesconi, Richard R. Fabsitz, Chin-Chi Kuo, Lyle Best, Richard B. Devereux, Jason G. Umans
Publikováno v:
American Journal of Epidemiology. 184:806-817
At high levels, inorganic arsenic exposure is linked to peripheral arterial disease (PAD) and cardiovascular disease. To our knowledge, no prior study has evaluated the association between low-to-moderate arsenic exposure and incident PAD by ankle br
Autor:
Michael Wolz, Mona Puggal, Paul D. Sorlie, Jean L. Olson, Pothur R. Srinivas, Cheryl Nelson, Gina S. Wei, Cashell E. Jaquish, Phyliss Sholinsky, George J. Papanicolaou, Kevin L. Purkiser, Sean Coady, Richard R. Fabsitz
Publikováno v:
Circulation. 132:2028-2033
In a recent article, Alberts et al1 warned that the US-based biomedical science enterprise is flawed in its assumption that the enterprise will constantly expand, and it cannot expect a persistently expanding National Institutes of Health (NIH) biome
Autor:
Laura Almasy, Barbara V. Howard, Sandra Laston, Elisa T. Lee, Lyle G. Best, Richard R. Fabsitz, Shelley A. Cole, Jean W. MacCluer, Nora Franceschini, Karin Haack, Jason G. Umans
Publikováno v:
Clinical Journal of the American Society of Nephrology. 9:150-158
Summary Background and objectives CKD disproportionally affects American Indians, who similar to other populations, show genetic susceptibility to kidney outcomes. Recent studies have identified several loci associated with kidney traits, but their r
Autor:
Cashell E. Jaquish, Pothur R. Srinivas, Sheri D. Schully, Richard R. Fabsitz, George J. Papanicolaou, Mona Puggal
Publikováno v:
Circulation: Cardiovascular Genetics. 6:634-639
The National Heart, Lung, and Blood Institute (NHLBI) is firmly committed to advancing translational research, especially in the field of genetics. An evaluation of the NHLBI’s extramural research grants funded in fiscal year 2008 and fiscal year 2