Zobrazeno 1 - 10 of 37 pro vyhledávání: '"Richard P. E. van Dokkum"'
1
Vildagliptin Restores Renal Myogenic Function and Attenuates Renal Sclerosis Independently of Effects on Blood Glucose or Proteinuria in Zucker Diabetic Fatty Rat
Autor: Yumei Wang, Richard P. E. van Dokkum, Sjoerd W. Landheer, Hendrik Buikema, Robert H. Henning, Peter Vavrinec, Leo E. Deelman
Publikováno v: Current Vascular Pharmacology, 12(6), 836-844. BENTHAM SCIENCE PUBL LTD
Type 2 diabetes mellitus (T2DM) is associated with risk for chronic kidney disease (CKD), which is associated with a decrease in renal myogenic tone - part of renal autoregulatory mechanisms. Novel class of drugs used for the treatment of T2DM, dipep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062c7716b6537f07ee37bbc0d557692e
https://doi.org/10.2174/15701611113116660151
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2
Tacrolimus-induced hypertension and nephrotoxicity in Fawn-Hooded rats are attenuated by dual inhibition of renin–angiotensin system
Autor: Luděk Červenka, Alžbeta Vojtíšková, Lenka Hošková, Josef Kautzner, Libor Kopkan, Eva Honsova, Šárka Varcabová, Zuzana Husková, Richard P. E. van Dokkum, Ivan Málek
Publikováno v: HYPERTENSION RESEARCH, 37(8), 724-732. Nature Publishing Group
Chronic immunosuppressive therapy is often complicated by the development of both arterial hypertension and renal dysfunction. The principal aim of this study was to assess the effects of dual inhibition of renin-angiotensin system (RAS) and other an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67491adf8d32d5ea379c6b961d122c4
https://doi.org/10.1038/hr.2014.79
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3
Pioglitazone, a PPARγ agonist, provides comparable protection to angiotensin converting enzyme inhibitor ramipril against adriamycin nephropathy in rat
Autor: Jan Klimas, Jan Kyselovic, Hana Cernecka, Peter Krenek, Robert H. Henning, Richard P. E. van Dokkum, Lucia Mesarosova, Peter Ochodnicky, Maaike Goris
Publikováno v: European journal of pharmacology, 730, 51-60. Elsevier
European Journal of Pharmacology, 730, 51-60. ELSEVIER SCIENCE BV
Peroxisome proliferator-activated receptor γ (PPARγ) agonists have been shown to ameliorate diabetic nephropathy, but much less are known about their effects in non-diabetic nephropathies. In the present study, metabolic parameters, blood pressure,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abdec833a7a03ca0f0b95c49f46aaf77
https://doi.org/10.1016/j.ejphar.2014.02.023
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4
Renal myogenic constriction protects the kidney from age-related hypertensive renal damage in the Fawn-Hooded rat
Autor: Richard P. E. van Dokkum, Sjoerd W. Landheer, Robert H. Henning, Maaike Goris, Peter Vavrinec, Hendrik Buikema
Publikováno v: Journal of Hypertension, 31(8), 1637-1645. LIPPINCOTT WILLIAMS & WILKINS
Introduction:Intact myogenic constriction plays a role in renal blood flow autoregulation and protection against pressure-related (renal) injury. However, to what extent alterations in renal artery myogenic constriction are involved in development of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5730f8c8e2bf4c5d0fee906f7e6b0116
https://doi.org/10.1097/hjh.0b013e328361d506
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5
Epidermal growth factor receptor inhibitor PKI-166 governs cardiovascular protection without beneficial effects on the kidney in hypertensive 5/6 nephrectomized rats
Autor: Gemma M. Mulder, Nadir Ulu, Sjoerd W. Landheer, Maaike Goris, Hakan Gurdal, Robert H. Henning, Basak Duman-Dalkilic, Hendrik Buikema, M Duin, Richard P. E. van Dokkum, Harry van Goor, Peter Vavrinec
Publikováno v: Journal of Pharmacology and Experimental Therapeutics, 345(3), 393-403. WILLIAMS & WILKINS
Transactivation of epidermal growth factor receptor (EGFR) signaling by G protein-coupled receptors has been implicated in several cardiovascular (CV) conditions, including hypertension, heart failure, and cardiac and vascular hypertrophy. However, t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519590fdc5fa6d86f3fd770d068d6479
https://doi.org/10.1124/jpet.113.203497
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6
Vascular smooth muscle function of renal glomerular and interlobar arteries predicts renal damage in rats
Autor: Peter Vavrinec, Maaike Goris, Hendrik Buikema, Richard P. E. van Dokkum, Robert H. Henning, Diana Vavrincova-Yaghi
Publikováno v: American journal of physiology-Renal physiology, 303(8), F1187-F1195. AMER PHYSIOLOGICAL SOC
Vavrinec P, Henning RH, Goris M, Vavrincova-Yaghi D, Buikema H, van Dokkum RP. Vascular smooth muscle function of renal glomerular and interlobar arteries predicts renal damage in rats. Am J Physiol Renal Physiol 303: F1187-F1195, 2012. First publish
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a765f8af3f7c5daa89872f49fa8e5a9
https://doi.org/10.1152/ajprenal.00653.2011
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7
Losartan protects mesenteric arteries from ROS-associated decrease in myogenic constriction following 5/6 nephrectomy
Autor: Robert H. Henning, Maaike Goris, Hendrik Buikema, Peter Vavrinec, Richard P. E. van Dokkum
Publikováno v: Journal of the Renin-Angiotensin-Aldosterone System, Vol 12 (2011)
Journal of the Renin-Angiotensin-Aldosterone System, 12(3), 184-194
Background: Chronic renal failure (CRF) is associated with hypertension, proteinuria, loss of myogenic constriction (MC) of mesenteric arteries and increased production of reactive oxygen species (ROS) under experimental conditions. Previous results
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc9b37400fe6e393dd34bb640324c3fe
https://hdl.handle.net/11370/23ac85c8-551e-48ca-887c-180c76cef8b7
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8
Renal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat
Autor: Dick de Zeeuw, Peter Ochodnický, Richard P. E. van Dokkum, Robert H. Henning, Abraham P. Provoost, Hendrik Buikema
Publikováno v: American journal of physiology-Renal physiology, 298(3), F625-F633. AMER PHYSIOLOGICAL SOC
American journal of physiology. Renal physiology, 298(3), F625-F633. American Physiological Society
Ochodnicky P, Henning RH, Buikema HJ, de Zeeuw D, Provoost AP, van Dokkum RP. Renal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat. Am J Physiol Renal Physiol 298: F625-F633, 2010. First published De
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825b99c1abdd63c2a853b499ccfcc2c3
https://doi.org/10.1152/ajprenal.00289.2009
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9
Possible new druggable targets for the treatment of nephrosis
Autor: Richard P. E. van Dokkum, Hendrik Buikema
Publikováno v: Current Opinion in Pharmacology. 9:132-138
Nephrosis refers to a condition resulting from proteinuric kidney disease, leading to irreversible renal parenchymal damage and end-stage renal disease when left untreated. Furthermore, nephrosis appears to be a communicable disease carrying risks an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf8ebc498424071f3ed126bd808986fd
https://doi.org/10.1016/j.coph.2008.12.008
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10
Myocardial infarction does not further impair renal damage in 5/6 nephrectomized rats
Autor: Ying Xu, Robert H. Henning, Willemijn A.K.M. Windt, Richard P. E. van Dokkum, Dick de Zeeuw, Alex C. A. Kluppel
Publikováno v: Nephrology Dialysis Transplantation, 23(10), 3103-3110. Oxford University Press
Background. Recent observational studies show that reduced renal function is an independent risk factor for the development of cardiovascular disease. Previously, we reported that myocardial infarction (MI) indeed enhanced mild renal function decline
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e872820eab6d16aac59322bc81d9dd64
https://doi.org/10.1093/ndt/gfn233
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