Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Richard P. Cohen"'
Autor:
Di Shao, Chunxiang Yao, Maya H. Kim, Jessica Fry, Richard A. Cohen, Catherine E. Costello, Reiko Matsui, Francesca Seta, Mark E. McComb, Markus M. Bachschmid
Publikováno v:
Redox Biology, Vol 22, Iss , Pp - (2019)
Sirtuin-1 (SirT1) catalyzes NAD+-dependent protein lysine deacetylation and is a critical regulator of energy and lipid metabolism, mitochondrial biogenesis, apoptosis, and senescence. Activation of SirT1 mitigates metabolic perturbations associated
Externí odkaz:
https://doaj.org/article/007efb9834d74e2bab6db56ca200aba3
Autor:
Jingyan Han, Robert M. Weisbrod, Di Shao, Yosuke Watanabe, Xiaoyan Yin, Markus M. Bachschmid, Francesca Seta, Yvonne M.W. Janssen-Heininger, Reiko Matsui, Mengwei Zang, Naomi M. Hamburg, Richard A. Cohen
Publikováno v:
Redox Biology, Vol 9, Iss C, Pp 306-319 (2016)
Background: Oxidative stress is implicated in increased vascular permeability associated with metabolic disorders, but the underlying redox mechanism is poorly defined. S-glutathionylation, a stable adduct of glutathione with protein sulfhydryl, is a
Externí odkaz:
https://doaj.org/article/ee6d870c9a0647c6b1c280a5ee1e2a98
Autor:
Edward J. Miller, Timothy Calamaras, Aly Elezaby, Aaron Sverdlov, Fuzhong Qin, Ivan Luptak, Ke Wang, Xinxin Sun, Andrea Vijay, Dominique Croteau, Markus Bachschmid, Richard A. Cohen, Kenneth Walsh, Wilson S. Colucci
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 1 (2016)
BackgroundMyocardial hypertrophy and dysfunction are key features of metabolic heart disease due to dietary excess. Metabolic heart disease manifests primarily as diastolic dysfunction but may progress to systolic dysfunction, although the mechanism
Externí odkaz:
https://doaj.org/article/5e3d41148a354572bb88926c7948ce0c
Autor:
Aaron L. Sverdlov, Aly Elezaby, Fuzhong Qin, Jessica B. Behring, Ivan Luptak, Timothy D. Calamaras, Deborah A. Siwik, Edward J. Miller, Marc Liesa, Orian S. Shirihai, David R. Pimentel, Richard A. Cohen, Markus M. Bachschmid, Wilson S. Colucci
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 1 (2016)
BackgroundMitochondrial reactive oxygen species (ROS) are associated with metabolic heart disease (MHD). However, the mechanism by which ROS cause MHD is unknown. We tested the hypothesis that mitochondrial ROS are a key mediator of MHD. Methods and
Externí odkaz:
https://doaj.org/article/cca659c2f7ae4f23b72a454022eded52
Autor:
Richard A. Cohen
Publikováno v:
Religions, Vol 10, Iss 1, p 7 (2018)
The purpose of this paper is to show that underlying Schmitt’s account of fascist politics lies a Gnostic-like metaphysical dualism separating the realms of value and power. Contrary to the normative political tradition of the West, which defends e
Externí odkaz:
https://doaj.org/article/5737dfc438e4404ebddc6fd134f8bebb
Autor:
Chunxiang Yao, Jessica B Behring, Di Shao, Aaron L Sverdlov, Stephen A Whelan, Aly Elezaby, Xiaoyan Yin, Deborah A Siwik, Francesca Seta, Catherine E Costello, Richard A Cohen, Reiko Matsui, Wilson S Colucci, Mark E McComb, Markus M Bachschmid
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144025 (2015)
Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H2O2), react with thiolates to form oxidative post-translational modifications, enabling physiological redox signaling. Cardiac disease and
Externí odkaz:
https://doaj.org/article/17226e23b1354d9a9df939a220b367f6
Autor:
Richard A. Cohen
Publikováno v:
Journal of French and Francophone Philosophy, Vol 10, Iss 2, Pp 152-170 (1998)
none
Externí odkaz:
https://doaj.org/article/3419201de47b4a42a8a155c749d3950b
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67532 (2013)
Aberrantly elevated sterol regulatory element binding protein (SREBP), the lipogenic transcription factor, contributes to the development of fatty liver and insulin resistance in animals. Our recent studies have discovered that AMP-activated protein
Externí odkaz:
https://doaj.org/article/48039fa3cd8143f09a7e91384db343e5
Autor:
Dagmar J Haeussler, Alicia M Evangelista, Joseph R Burgoyne, Richard A Cohen, Markus M Bachschmid, David R Pimental
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23160 (2011)
Adenoviruses are widely used for overexpressing proteins in primary mammalian cells. Incorporation of the early viral gene, E1A, or viral cross-contamination can occur during amplification, and identification of these products is crucial as the trans
Externí odkaz:
https://doaj.org/article/68126fb7c4bc4e34b0120abaed92c0b7
Publikováno v:
American Journal of Gastroenterology. 116:S918-S918