Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Richard P. Bunge"'
Autor:
Les Olson, R.J. Wieser, Jennifer L. Katz, Gizelda T. Casella, Irene S. Margitich, Patrick M. Wood, Richard P. Bunge
Publikováno v:
Glia. 30:165-177
Cessation of division is prerequisite for Schwann cell differentiation but regulation of this critical function is poorly understood. Heregulin/forskolin-induced growth of human Schwann cells (HSCs) in vitro was found to be strongly regulated by cell
Autor:
Richard P. Bunge, Claudia N. Montero-Menei, Scott R. Whittemore, Philippe Menei, Mary Bartlett Bunge
Publikováno v:
European Journal of Neuroscience. 10:607-621
The infusion of BDNF and NT-3 into Schwann cell (SC) grafts promotes regeneration of brainstem neurones into the grafts placed in adult rat spinal cord transected at T8 (Xu et al., 1995b). Here, we compared normal SCs with SCs genetically modified to
Autor:
Lisa Schnell, Donald H. Hesse, Martin E. Schwab, Richard P. Bunge, James D. Guest, Mary Bartlett Bunge
Publikováno v:
Journal of Neuroscience Research. 50:888-905
Two strategies have been shown by others to improve CST regeneration following thoracic spinal cord injury: 1) the administration of a monoclonal antibody, IN-1, raised against a myelin-associated, neurite growth inhibitory protein, and 2) the delive
Publikováno v:
Glia. 17:327-338
The use of cellular prostheses containing large populations of Schwann cells (SC) has been proposed as a future therapeutic approach in the repair of neural tissue. We have sought to define an efficient protocol for the harvest and expansion of human
Publikováno v:
Neurosurgery. 38:179-185
Patients with cervical spinal cord injuries who present with weakness or paralysis of the hands and arms with relative preservation of lower extremity strengths are often categorized as having two clinical syndromes, cruciate paralysis and acute cent
Publikováno v:
Journal of Neurobiology. 28:171-189
Schwann cells (SCs) play critical roles in regeneration after injury to the peripheral nervous system and can also induce axonal regeneration in the central nervous system. Transplantation of purified SCs into sites of neural injury in rodents has co
Publikováno v:
Proceedings of the National Academy of Sciences. 92:1431-1435
The ability of sensory axons to stimulate Schwann cell proliferation by contact was established in the 1970s. Although the mitogen responsible for this proliferation has been localized to the axon surface and biochemically characterized, it has yet t
Autor:
Julie A. Lofgren, Allan D. Levi, Richard P. Bunge, Leonie Meima, Mark X. Sliwkowski, Franz Hefti, Karoly Nikolics
Publikováno v:
The Journal of Neuroscience. 15:1329-1340
The use of Schwann cell (SC) autotransplantation to influence neural repair in humans is dependent upon identifying mitogens that will effectively expand human Schwann cells (SCs) in culture. The recent purification and molecular cloning of glial gro
Autor:
Richard P. Bunge, Allan D. Levi
Publikováno v:
Experimental Neurology. 130:41-52
We have previously demonstrated (J. Neurosci., 14: 1309-1319) that Schwann cells (SCs) isolated from adult human peripheral nerve in tissue culture and then transplanted into an immune-deficient rat can enhance axonal regeneration and myelinate regen
Publikováno v:
Experimental Neurology. 124:372-376
In some cases of spinal cord injury and in certain motoneuron diseases, such as amyotrophic lateral sclerosis and spinal muscular atrophies, lower motoneurons are destroyed and muscle function cannot be restored except by reinnervation from alternate