Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Richard P, Hulse"'
Publikováno v:
Current Research in Physiology, Vol 5, Iss , Pp 184-192 (2022)
Nociception is a fundamental acute protective mechanism that prevents harm to an organism. Understanding the integral processes that control nociceptive processing are fundamental to our appreciation of which cellular and molecular features underlie
Externí odkaz:
https://doaj.org/article/4e6d3f15db574c6584ba795fe8d7ae88
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Chemotherapy causes sensory disturbances in cancer patients that results in neuropathies and pain. As cancer survivorships has dramatically increased over the past 10 years, pain management of these patients is becoming clinically more important. Cur
Externí odkaz:
https://doaj.org/article/b0e3a4b9ca694d3e8fb0da4b2a39ee16
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 186-200 (2016)
Neuropathic pain results from neuroplasticity in nociceptive neuronal networks. Here we demonstrate that control of alternative pre-mRNA splicing, through the splice factor serine-arginine splice factor 1 (SRSF1), is integral to the processing of noc
Externí odkaz:
https://doaj.org/article/48cc6e43d9a74931b454519581875e44
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2441
The spinal cord, a compartment of the central nervous system, is made up of a number of architecturally distinct neural centers that influence an array of neurophysiological systems. The primary role of the spinal cord is the modulation of sensory an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8de6d90550873d7eee2e09ee8680af4c
https://pubmed.ncbi.nlm.nih.gov/35099738
https://pubmed.ncbi.nlm.nih.gov/35099738
Autor:
Richard P. Hulse, David O. Bates, Lucy F. Donaldson, William Robert Ashby, Fatimah Almahasneh, Alexandra M. Durrant, Samuel M. Bestall, Catherine E. Moss, Kurt Ballmer-Hofer, Andrew V. Benest, Nicholas Beazley-Long, Zoe Blackley, Masanori Hirashima
Publikováno v:
Brain, Behavior, and Immunity
BRAIN BEHAVIOR AND IMMUNITY
BRAIN BEHAVIOR AND IMMUNITY
Highlights • Targeting VEGFR2 prevents secondary allodynia in inflammatory arthritis models. • Anti-VEGFR2 reduces vascular ICAM-1 and microglia in the dorsal horn. • Anti-VEGFR2 inhibits monocyte attachment to brain endothelial cells. • We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e38cc8fad778f1572a48ea858082b3
https://hdl.handle.net/20.500.14094/90005492
https://hdl.handle.net/20.500.14094/90005492
Autor:
David O. Bates, Nicholas Beazley-Long, Richard P. Hulse, Sebastian Oltean, Maria Peiris-Pagès, Nikita Ved, Xi Ye, Rebecca R. Foster, Domingo J. Tortonese, Maria J. C. Machado, Steven J. Harper, Andrew V. Benest, Shaney L Barratt, Lucy F. Donaldson
Publikováno v:
Bates, D O, Beazley-Long, N, Benest, A, Ye, X, Ved, N, Hulse, R, Barratt, S, Machado, M, Donaldson, L F, Harper, S, Peiris-Pages, M, Tortonese, D, Oltean, S & Foster, R R 2018, ' Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators ', Comprehensive Physiology, vol. 8, no. 3, pp. 955-979 . https://doi.org/10.1002/cphy.c170015
Comprehensive Physiology
Comprehensive Physiology
The vascular endothelial growth factor (VEGF) family of proteins are key regulators of physiological systems. Originally linked with endothelial function, they have since become understood to be principal regulators of multiple tissues, both through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9e7fd7c06c6937ecc69ab82b4d61a5
https://pubmed.ncbi.nlm.nih.gov/29978898
https://pubmed.ncbi.nlm.nih.gov/29978898
Autor:
Samuel M, Bestall, Richard P, Hulse, Zoe, Blackley, Matthew, Swift, Nikita, Ved, Kenneth, Paton, Nicholas, Beazley-Long, David O, Bates, Lucy F, Donaldson
Publikováno v:
Journal of Cell Science
Many potential causes for painful diabetic neuropathy have been proposed including actions of cytokines and growth factors. High mobility group protein B1 (HMGB1) is a RAGE (also known as AGER) agonist whose levels are increased in diabetes and that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0f138403a93a51988036d4ceb23bce7
https://pubmed.ncbi.nlm.nih.gov/29930087
https://pubmed.ncbi.nlm.nih.gov/29930087
Autor:
Lucy F. Donaldson, Priya Singhal, Kurt Ballmer Hofer, Samuel M. Bestall, Nicholas Beazley-Long, Hamza Riaz, Richard P. Hulse, Nikita Ved, Steve J Harper, David O. Bates
Publikováno v:
Clinical science (London England : 1979)
Diabetic peripheral neuropathy affects up to half of diabetic patients. This neuronal damage leads to sensory disturbances, including allodynia and hyperalgesia. Many growth factors have been suggested as useful treatments for prevention of neurodege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::266bf0f2be4b949b960ba3ad42a5a0a6
Autor:
Richard P. Hulse, James W B Bainbridge, Nikita Ved, David O. Bates, Lucy F. Donaldson, Samuel M. Bestall
Publikováno v:
Clinical Science.
Diabetic retinopathy (DR) is one of the leading causes of blindness in the developed world. Characteristic features of DR are retinal neurodegeneration, pathological angiogenesis and breakdown of both the inner and outer retinal barriers of the retin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3586c9f91c72e5630940ba5db2b949
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Publikováno v:
Oncotarget
The tumour and neuron interaction has a significant impact upon disease progression and the patients quality of life. In breast cancer patients, it is known that there is an interaction between the tumour microenvironment and the sensory neurons to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cfca6199731c0aad1f9120f48bd6e4
https://pubmed.ncbi.nlm.nih.gov/29100335
https://pubmed.ncbi.nlm.nih.gov/29100335