Výsledky vyhledávání - "Richard Odle"

Data from Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2

Autor: Simon J. Cook, Richard Odle, Marc O'Reilly, Brent Graham, Aurelie Courtin, Emma Minihane, Kathryn Balmanno, Harpreet K. Saini, Joanne M. Munck, Andrew M. Kidger

The RAS-regulated RAF-MEK1/2-ERK1/2 signaling pathway is frequently deregulated in cancer due to activating mutations of growth factor receptors, RAS or BRAF. Both RAF and MEK1/2 inhibitors are clinically approved and various ERK1/2 inhibitors (ERKi)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f75a06a552ccae6e14211a5956c6395
https://doi.org/10.1158/1535-7163.c.6542839

Zobrazit plný text záznamu

Supplementary Data from Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2

Autor: Simon J. Cook, Richard Odle, Marc O'Reilly, Brent Graham, Aurelie Courtin, Emma Minihane, Kathryn Balmanno, Harpreet K. Saini, Joanne M. Munck, Andrew M. Kidger

Supplementary Tables and Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5109fc882ed9ce4603d93a4796b6f2f3
https://doi.org/10.1158/1535-7163.22520935.v1

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání