Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Richard O‘Connor"'
Autor:
Akshika Sharma, Brian Fix, Andrew Hyland, Maansi Bansal-Travers, Amanda Quisenberry, Richard O’Connor
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
IntroductionIQOS was authorized to be marketed as a reduced exposure product by the Food and Drug Administration in October 2020 during the global COVID-19 pandemic. Those who smoke may be more sensitive to reduced exposure marketing claims and may h
Externí odkaz:
https://doaj.org/article/f4e877df4ae54a3eaae17ab225af59c5
Autor:
Richard O’Connor, David A Dorward, Ahsan R Akram, Lilian Koppensteiner, Layla Mathieson, Samuel Pattle
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)
Purpose An improved mechanistic understanding of immunosuppressive pathways in non-small cell lung cancer (NSCLC) is important to develop novel diagnostic and therapeutic approaches. Here, we investigate the prognostic significance of the ectonucleot
Externí odkaz:
https://doaj.org/article/aa9f797358354e38a4f06c44b000a342
Autor:
Bill King, Ron Borland, Michael Le Grande, Destiny Diaz, Richard O'Connor, Katherine East, Eve Taylor, Coral Gartner, Hua-Hie Yong
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292856 (2023)
BackgroundMost smokers know that smoking is harmful to health, but less is known about their understanding of what causes the harms. The primary aim was to examine smokers' perceptions of the relative contributions to smoking-related morbidity from c
Externí odkaz:
https://doaj.org/article/13e6f8294aff4a6e887343fea8425edc
Autor:
Katie J Smith, Danielle Minns, Brian J McHugh, Rebecca K Holloway, Richard O'Connor, Anna Williams, Lauren Melrose, Rhoanne McPherson, Veronique E Miron, Donald J Davidson, Emily Gwyer Findlay
Publikováno v:
PLoS Biology, Vol 20, Iss 8, p e3001554 (2022)
Multiple sclerosis (MS) is a highly prevalent demyelinating autoimmune condition; the mechanisms regulating its severity and progression are unclear. The IL-17-producing Th17 subset of T cells has been widely implicated in MS and in the mouse model,
Externí odkaz:
https://doaj.org/article/6092c03798ea4893825a68dc61de5313
Autor:
Tom M. Quinn, Erin E. Gaughan, Annya Bruce, Jean Antonelli, Richard O'Connor, Feng Li, Sarah McNamara, Oliver Koch, Claire MacKintosh, David Dockrell, Timothy Walsh, Kevin G. Blyth, Colin Church, Jürgen Schwarze, Cecilia Boz, Asta Valanciute, Matthew Burgess, Philip Emanuel, Bethany Mills, Giulia Rinaldi, Gareth Hardisty, Ross Mills, Emily Gwyer Findlay, Sunny Jabbal, Andrew Duncan, Sinéad Plant, Adam D.L. Marshall, Irene Young, Kay Russell, Emma Scholefield, Alastair F. Nimmo, Islom B. Nazarov, Grant C. Churchill, James S.O. McCullagh, Kourosh H. Ebrahimi, Colin Ferrett, Kate Templeton, Steve Rannard, Andrew Owen, Anne Moore, Keith Finlayson, Manu Shankar-Hari, John Norrie, Richard A. Parker, Ahsan R. Akram, Daniel C. Anthony, James W. Dear, Nik Hirani, Kevin Dhaliwal
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103856- (2022)
Summary: Background: Many repurposed drugs have progressed rapidly to Phase 2 and 3 trials in COVID19 without characterisation of Pharmacokinetics /Pharmacodynamics including safety data. One such drug is nafamostat mesylate. Methods: We present the
Externí odkaz:
https://doaj.org/article/30aabc317f5544bcb011f0340db28762
Publikováno v:
JMIR Formative Research, Vol 5, Iss 6, p e25010 (2021)
BackgroundA cross-sectional study (Miyara et al, 2020) conducted by French researchers showed that the rate of current daily smoking was significantly lower in patients with COVID-19 than in the French general population, implying a potentially prote
Externí odkaz:
https://doaj.org/article/6dc24a82c5e5453aaaeffdf14ccfcf0c
Autor:
Fangyi Gu, Eduardo Cortes Gomez, Jianhong Chen, Matthew F. Buas, Nicolas F. Schlecht, Karen Hulme, Shweta Vishwas Kulkarni, Prashant K. Singh, Richard O’Connor, Christine B. Ambrosone, Anurag K. Singh, Jianmin Wang
Publikováno v:
Journal of Circadian Rhythms, Vol 19, Iss 1 (2021)
Background: To address a critical gap for application of cancer chronotherapy of when would be the best time(s) for treating an individual cancer patient, we conducted a pilot study to characterize diurnal variations of gene expression in oral mucosa
Externí odkaz:
https://doaj.org/article/1f55062479da4e26aabcb4e025d8b409
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/09ce6ef375e140528cc707720b0b7790
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Study of the c-Met-HGF axis in non-small cell lung cancer (NSCLC) has focused on the roles of c-MET signaling in neoplastic epithelial cells and the secretion of its ligand hepatocyte growth factor (HGF) by tumor stromal cells. However, there is incr
Externí odkaz:
https://doaj.org/article/6ac609bced4c4ca9b33410a54bc2c7fd
Publikováno v:
Preventive Medicine Reports, Vol 7, Iss C, Pp 11-15 (2017)
Print and television advertisements for e-cigarettes are currently legal in the United States. Given that e-cigarettes are a lower-risk alternative to cigarettes, these ads could have a positive public health impact if they motivate smokers to switch
Externí odkaz:
https://doaj.org/article/04b1febd80bc4ca98862a1460cb8370c