Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Richard O'Laughlin"'
Autor:
Elizabeth Stasiowski, Richard O’Laughlin, Shayna Holness, Nicholas Csicsery, Jeff Hasty, Nan Hao
Publikováno v:
Bio-Protocol, Vol 13, Iss 22 (2023)
The relative ease of genetic manipulation in S. cerevisiae is one of its greatest strengths as a model eukaryotic organism. Researchers have leveraged this quality of the budding yeast to study the effects of a variety of genetic perturbations, such
Externí odkaz:
https://doaj.org/article/bd888206475d4670ac60b8d5c87a7e23
Publikováno v:
Bio-Protocol, Vol 13, Iss 15 (2023)
For several decades, aging in Saccharomyces cerevisiae has been studied in hopes of understanding its causes and identifying conserved pathways that also drive aging in multicellular eukaryotes. While the short lifespan and unicellular nature of budd
Externí odkaz:
https://doaj.org/article/62863b7381da4f65bb11ae070e5981d0
Autor:
Julie Paxman, Zhen Zhou, Richard O'Laughlin, Yuting Liu, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E Holness, Elizabeth Stasiowski, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
Publikováno v:
eLife, Vol 11 (2022)
Chromatin instability and protein homeostasis (proteostasis) stress are two well-established hallmarks of aging, which have been considered largely independent of each other. Using microfluidics and single-cell imaging approaches, we observed that, d
Externí odkaz:
https://doaj.org/article/8b123c5e430f4c03951e121b50a9be75
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss , Pp 151-160 (2020)
Aging is a complex, yet pervasive phenomenon in biology. As human cells steadily succumb to the deteriorating effects of aging, so too comes a host of age-related ailments such as neurodegenerative disorders, cardiovascular disease and cancer. Theref
Externí odkaz:
https://doaj.org/article/15f33c91c5894ffb88187e73b51b188c
Autor:
Zhen Zhou, Julie Paxman, Richard O'Laughlin, Yuting Liu, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E Holness, Elizabeth Stasiowski, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
Chromatin instability and protein homeostasis (proteostasis) stress are two well-established hallmarks of aging, which have been considered largely independent of each other. Using microfluidics and single-cell imaging approaches, we observed that, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7390565de28c9cee00d7665579630c10
https://escholarship.org/uc/item/96h8k9h8
https://escholarship.org/uc/item/96h8k9h8
Autor:
Zhen Zhou, Julie Paxman, Richard O'Laughlin, Yuting Liu, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E Holness, Elizabeth Stasiowski, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5af0cacc07463f14d0a9e1f9180db9b
https://doi.org/10.7554/elife.75978.sa2
https://doi.org/10.7554/elife.75978.sa2
Publikováno v:
Curr Opin Neurobiol
The emerging technology of brain organoids deriving from human pluripotent stem cells provides unprecedented opportunities to study human brain development and associated disorders. Various brain organoid protocols have been developed that can recapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a756b23cb5a71b8d501d8ea57bca767b
https://europepmc.org/articles/PMC9167774/
https://europepmc.org/articles/PMC9167774/
Publikováno v:
Translational Medicine of Aging, Vol 4, Iss, Pp 151-160 (2020)
Aging is a complex, yet pervasive phenomenon in biology. As human cells steadily succumb to the deteriorating effects of aging, so too comes a host of age-related ailments such as neurodegenerative disorders, cardiovascular disease and cancer. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23c02571cdfe7f4cb7cd36ed1bbf271
http://www.sciencedirect.com/science/article/pii/S2468501119300112
http://www.sciencedirect.com/science/article/pii/S2468501119300112
Autor:
Julie Paxman, Zhen Zhou, Richard O’Laughlin, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E. Holness, Elizabeth Stasiowski, Lev S. Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
SummaryChromatin instability and loss of protein homeostasis (proteostasis) are two well-established hallmarks of aging, which have been considered largely independent of each other. Using microfluidics and single-cell imaging approaches, we observed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7050b11a2bb0502d90f5d0428183ac5
https://doi.org/10.1101/2021.12.06.471495
https://doi.org/10.1101/2021.12.06.471495
Autor:
Richard, O'Laughlin, Meng, Jin, Yang, Li, Lorraine, Pillus, Lev S, Tsimring, Jeff, Hasty, Nan, Hao
Publikováno v:
Translational medicine of aging
Aging is a complex, yet pervasive phenomenon in biology. As human cells steadily succumb to the deteriorating effects of aging, so too comes a host of age-related ailments such as neurodegenerative disorders, cardiovascular disease and cancer. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6740ebdb545635155f60c33c7083785a
https://pubmed.ncbi.nlm.nih.gov/33880425
https://pubmed.ncbi.nlm.nih.gov/33880425