Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Richard Noring"'
Autor:
Robert Bousquet, Brenda Hugh, Brian T. Cunningham, Anthony Petrovich, Christopher Clapp, Jane Pepper, Jeanne M. Brady, Richard Noring, Mark S. Klempner
Publikováno v:
Sensors and Actuators B: Chemical. 96:565-575
We are developing biosensor arrays that are based on microfabricated silicon flexural plate wave (FPW) resonators coated with molecular recognition chemistry. The resonators within the micro-chemical analysis array (CANARY) are micro-electromechanica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50288718a366c5340e4114e924cb960f
https://doi.org/10.1016/s0925-4005(03)00641-5
https://doi.org/10.1016/s0925-4005(03)00641-5
Publikováno v:
The Journal of Infectious Diseases. 184:174-180
The cause of persistent arthritis in patients with Lyme disease who have received standard antibiotic therapy remains an area of debate. In this study, synovial fluid levels of matrix metalloproteinases (MMPs) were compared in persons with untreated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106b0f6675cc10c6ebefb8f7b220828f
https://doi.org/10.1086/322000
https://doi.org/10.1086/322000
Publikováno v:
The Journal of Infectious Diseases. 181:1185-1188
Levels of circulating soluble CD14 (sCD14) in patients with various stages of Lyme disease (LD) were examined. Patients with early or untreated late LD had significantly higher levels of sCD14 than did healthy controls (P=.0001 and .0007, respectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36f4cda3e0bc5fdcd7086ad2470a090
https://doi.org/10.1086/315357
https://doi.org/10.1086/315357
Publikováno v:
Biochemical and Biophysical Research Communications. 219:690-695
Lyme disease is caused by Borrelia burgdorferi. Human plasminogen and urokinase-type plasminogen activator bind to the surface of the spirochete where plasmin is generated. We have suggested that bound urokinase and plasminogen are utilized by the or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e14118b674db2a233cd521733627c48
https://doi.org/10.1006/bbrc.1996.0296
https://doi.org/10.1006/bbrc.1996.0296
Autor:
Mark S. Klempner, Richard Noring, Rick A. Rogers, Steven A. Limentani, Mark P. Epstein, Rong Hu, Bruce McCloud
Publikováno v:
Journal of Infectious Diseases. 171:1258-1265
Many bacteria that spread in the skin produce enzymes that digest extracellular matrix components. Borrelia burgdorferi spreads from a skin inoculation site to form the characteristic erythema migrans skin lesion. It was determined that B. burgdorfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6446781813a1bcd4da97801777a79dad
https://doi.org/10.1093/infdis/171.5.1258
https://doi.org/10.1093/infdis/171.5.1258
Autor:
Mark S. Klempner, Linden T. Hu, Bilaal McCloud, Arthur Weinstein, Christopher H. Schmid, Allen C. Steere, Gary M. Johnson, Richard Noring
Publikováno v:
The American Journal of Medicine. 110:217-219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b9e9e48525dc4a43aa6bdb2c49f82e
https://doi.org/10.1016/s0002-9343(00)00701-4
https://doi.org/10.1016/s0002-9343(00)00701-4
Autor:
Mark S. Klempner, Michael B. Atkins, James W. Mier, Wally Laird, Frederick R. Aronson, Eugene P. Brandon, Richard Noring, Gloria Vachino, Steve Smith
Publikováno v:
Blood. 76:1933-1940
High concentrations of tumor necrosis factor (TNF) alpha have been detected in the plasma of patients undergoing immunotherapy with interleukin 2 (IL-2), suggesting that this cytokine may play a role in the fever and shocklike state induced by the ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12db350a109d554f3fea03f69c6cf1e1
https://doi.org/10.1182/blood.v76.10.1933.1933
https://doi.org/10.1182/blood.v76.10.1933.1933
Autor:
J. Michael Kidder, Mark S. Klempner, Joanna P. Scagliotti, Linden T. Hu, Xing-Guo Wang, Richard Noring
The Borrelia burgdorferi genome encodes five orthologues of the substrate binding protein oligopeptide permease A (OppA). It was previously shown that these genes are under the control of separate promoters and are differentially expressed under vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cce83b166220cf72a9da8384c2cc17
https://europepmc.org/articles/PMC365673/
https://europepmc.org/articles/PMC365673/
Autor:
Zev Gechtman, Stephen Capodilupo, Julio Herrera, Jacob Knowles, Richard Noring, Roberto Campos-González
Publikováno v:
Molecular Cancer Therapeutics. 12:C202-C202
The receptor tyrosine kinase (RTK) family comprises important disease drivers and validated drug targets. Cooperation between certain RTKs is often achieved through physical interactions and is thought be a contributing factor to some cases of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e128d3236bee35a76e0062335621c1ca
https://doi.org/10.1158/1535-7163.targ-13-c202
https://doi.org/10.1158/1535-7163.targ-13-c202
Publikováno v:
The Journal of infectious diseases. 174(1)
Borrelia burgdorferi binds human urokinase plasminogen activator (uPA), which cleaves plasminogen (Pgn) to plasmin. The ability of other Borrelia species to bind uPA, Pgn, or both was investigated. Borrelia coriacae, Borrelia garinii, Borrelia parker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49bcf06a86c1b05b289aba8d3b250f4
https://pubmed.ncbi.nlm.nih.gov/8656020
https://pubmed.ncbi.nlm.nih.gov/8656020